DNA芯片技术

DNA芯片可用于核酸序列的测定及基因突变检测等,这里对DNA芯片的制作、作用原理、性能及用途等进行了综述。     

Designing and integrating composite networks for monitoring multivariate gaussian pollution fields

Networks of ambient monitoring stations are used to monitor environmental pollution fields such as those for acid rain and air pollution. Such stations provide regular measurements of pollutant concentrations. The networks are established for a variety of purposes at various times so often several stations measuring different subsets of pollutant concentrations can be found in compact geographical regions. The problem of statistically combining these disparate information sources into a single 'network' then arises. Capitalizing on the efficiencies so achieved can then lead to the secondary problem of extending this network. The subject of this paper is a set of 31 air pollution monitoring stations in southern Ontario. Each of these regularly measures a particular subset of ionic sulphate, sulphite, nitrite and ozone. However, this subset varies from station to station. For example only two stations measure all four. Some measure just one. We describe a Bayesian framework for integrating the measurements of these stations to yield a spatial predictive distribution for unmonitored sites and unmeasured concentrations at existing stations. Furthermore we show how this network can be extended by using an entropy maximization criterion. The methods assume that the multivariate response field being measured has a joint Gaussian distribution conditional on its mean and covariance function. A conjugate prior is used for these parameters, some of its hyperparameters being fitted empirically.     

Bayes linear analysis for graphical models: The geometric approach to local computation and interpretive graphics

This paper concerns the geometric treatment of graphical models using Bayes linear methods. We introduce Bayes linear separation as a second order generalised conditional independence relation, and Bayes linear graphical models are constructed using this property. A system of interpretive and diagnostic shadings are given, which summarise the analysis over the associated moral graph. Principles of local computation are outlined for the graphical models, and an algorithm for implementing such computation over the junction tree is described. The approach is illustrated with two examples. The first concerns sales forecasting using a multivariate dynamic linear model. The second concerns inference for the error variance matrices of the model for sales, and illustrates the generality of our geometric approach by treating the matrices directly as random objects. The examples are implemented using a freely available set of object-oriented programming tools for Bayes linear local computation and graphical diagnostic display.     

Payment by results in international development: Evidence from the first decade

Payment by results is a relatively new way of giving development aid, where a recipient's performance against pre‐agreed measures determines the amount of aid they receive. Advocates for the mechanism argue it provides donors with both a ready justification for maintaining aid budgets and better results through innovation and autonomy. It has proved popular, with most bilateral aid donors having at least experimented with the mechanism and the variety of measures stretching from individual health workers being paid for each procedure, to national governments being paid for students' test scores. However, there has not been a robust assessment of whether Payment By Results (PbR) achieves its aims for greater effectiveness. I synthesize the evidence from eight projects fully or partially funded by DFID, the recognized world leader on PbR. This represents the best evidence currently available, and is critically analysed using the leading theoretical framework that breaks each agreement into its constituent parts. I find no evidence that PbR leads to fundamentally more innovation or autonomy, with the overall range of success and failure broadly similar to other aid projects. This may partly be due to the current use of Payment by Results, with no readily identifiable examples of projects that truly meet the idealized PbR designs. Advocates of PbR may thus conclude the idea is yet to be tested. I argue PbR does not deal with the fundamental constraints that donors face, and so it is unsurprising that PbR is subject to the normal pressures that affect all aid spending.     

Let the right one in: A Bourdieusian analysis of gender inequality in universities’ senior management

This article examines the lack of gender diversity in senior management positions in professional staff in universities. These results are analysed via a Bourdieusian analysis of economic, social, cultural and symbolic capital. Through a purposeful sample of senior professional staff working in universities in three countries: Australia, Canada and the UK, six career‐enhancing strategies needed for career success were determined. The article critiques the resource‐based view of career capital and argues that capitals accumulation for career success can be understood by considering the concepts of symbolic violence and habitus as a way of understanding intra‐cohort differences. It proposes that by considering both the subjective and objective cultural constructs via habitus, and by acknowledging the importance of symbolic capital and symbolic violence towards women, this may be one way of increasing female representation in senior management.     

Getting low educated and older people into work: The role of fiscal policy

Raising employment, in particular employment among older individuals and low educated individuals, stands high on the agenda of policy makers in many OECD countries. Increased sensitivity in recent years to rising inequality has made the challenge only larger. In this paper we evaluate alternative fiscal policy scenarios to face this challenge. We construct and use an overlapping generations model for an open economy where individuals differ not only by age, but also by innate ability and human capital. The model allows us to study effects on aggregate employment, per capita income and welfare, as well as effects for specific age and ability groups. We show that well-considered fiscal policy changes can significantly improve macroeconomic productive efficiency, without increasing intergenerational or intragenerational welfare inequality. Our results strongly prefer a reduction in the labor tax rate on older workers and on all low-wage earners, financed by an overall reduction in non-employment benefits. An alternative financing option is to raise the consumption tax rate. These results are to be seen as long-run effects for economies at potential output.     

江泽民依法治国思想探析

以江泽民同志为核心的第三代领导集体,首次提出了"依法治国,建设社会主义法治国家"的治国方略。准确把握江泽民同志依法治国的科学内涵,德治与法治的相互关联以及建设法治国家的主要途径等法治思想,对于全面建设社会主义小康社会和和谐社会意义深远。     

司法工作人员参与无身份者实施真正身份犯的共犯成立类型研究

根据共犯处罚的根据论中的修正惹起说,以及对实行行为的实质理解,在司法工作人员参与无身份者实施以司法工作人员身分作为构成要素的真正身份犯时,司法工作人员只能构成间接正犯,而不能构成教唆犯。而无身份者只能构成帮助犯,不能构成实行犯。     

刑事司法沉默权刍议

沉默权是刑事诉讼中,犯罪嫌疑人、被告人享有的一项自然权利,是无罪推定原则的延伸。西方大多数国家在刑事诉讼中采取了沉默权制度,中国目前尚未有关于沉默权的明确规定。我国应借鉴国外的经验,加强立法确立沉默权制度,以完善我国刑事司法制度。     

党的先进性建设与社会主义办学方向

高等院校党员先进性教育,要围绕“坚定社会主义办学方向”。如何把握社会主义办学方向?一是要进一步巩固马克思主义在高校的指导地位;二是高校的党政领导要成为社会主义政治家、教育家。