Measurement Error Correction by Exploiting Gene–Environment Independence in Family‐Based Case–Control Studies

Abstract. Family‐based case–control designs are commonly used in epidemiological studies for evaluating the role of genetic susceptibility and environmental exposure to risk factors in the etiology of rare diseases. Within this framework, it is often reasonable to assume genetic susceptibility and environmental exposure being conditionally independent of each other within families in the source population. We focus on this setting to explore the situation of measurement error affecting the assessment of the environmental exposure. We correct for measurement error through a likelihood‐based method. We exploit a conditional likelihood approach to relate the probability of disease to the genetic and the environmental risk factors. We show that this approach provides less biased and more efficient results than that based on logistic regression. Regression calibration, instead, provides severely biased estimators of the parameters. The comparison of the correction methods is performed through simulation, under common measurement error structures.     

内向的小佳如何变成孩子王——幼儿交往发展中的家庭影响因素典型个案研究

交往能力在个体终身成长中的作用显著，家庭是影响幼儿交往能力发展的至关重要的环境。本文通过对一则典型案例的调查访谈，梳理分析，揭示了在一个孩子交往行为发展进程中家庭因素的变化，以及可能对幼儿交往行为造成的影响。鲜活生动的事例便于身处其中的幼儿父母、幼教工作者们对照反思，以获取实用的育儿心得，对培养幼儿交往行为的发展具有一定指导和借鉴意义。     

Single Parent Families

No abstract available for this article.     

Lesbian-Headed Stepfamilies

Abstract

This paper examines the lesbian stepfamily. It considers the family structure, parenting roles, gender composition of the couple, the distribution of family labor, and the impact of familial and community support. It discusses some of the challenges facing lesbian-headed stepfamilies, their strengths, capacities and competencies, and the strategies these families use for coping with stigma and intolerance. The paper concludes with implications for policy and practice with lesbian stepfamilies.     

Confronting Anxiety in Couple and Family Therapy Supervision: A Developmental Supervisory Model Based on Attachment Theory

Referencing relevant supervisory literature and attachment theory, this article presents a developmental couple and family therapy supervisory model that emphasises the efficacy of the supervisory relationship. Issues concerning anxiety, cognition and learning theory are addressed and phases in the supervisory process are identified and described. Cognitive, emotional and social development are linked to attachment theory and discussed in the supervisory context.     

On the simple step-stress model for two-parameter exponential distribution

In this paper, we consider the simple step-stress model for a two-parameter exponential distribution, when both the parameters are unknown and the data are Type-II censored. It is assumed that under two different stress levels, the scale parameter only changes but the location parameter remains unchanged. It is observed that the maximum likelihood estimators do not always exist. We obtain the maximum likelihood estimates of the unknown parameters whenever they exist. We provide the exact conditional distributions of the maximum likelihood estimators of the scale parameters. Since the construction of the exact confidence intervals is very difficult from the conditional distributions, we propose to use the observed Fisher Information matrix for this purpose. We have suggested to use the bootstrap method for constructing confidence intervals. Bayes estimates and associated credible intervals are obtained using the importance sampling technique. Extensive simulations are performed to compare the performances of the different confidence and credible intervals in terms of their coverage percentages and average lengths. The performances of the bootstrap confidence intervals are quite satisfactory even for small sample sizes.     

A Postmodern Critique of Societal Discourses of Male Violence in Interpersonal Family Relationships: A Balancing Act for Social Work

In recent years, treatments of family violence have tended to be built around conventional discourses suggesting that men are major initiators in instances of interpersonal violence. Utilizing a postmodernist analysis, we assess societal discourses that continue to give life to this narrow conceptualization of interpersonal violence. We also examine literature suggesting that both men and women resort to violence to resolve relationship difficulties and suggest that a more holistic and inclusive approach to understanding interpersonal violence is critical for social workers committed to social justice and a balanced understanding of the contextual nature of human problems.     

汉代家产继承析论

汉代家庭财产继承由诸子平均分割和继承,汉代家产继承主要有父母在世时的＂生分＂和父母身后的析分两种方式。诸子均分制造成了汉代社会个体小家庭为主流的家庭形态。     

Ability vs Background: An Analysis of the Distribution Mechanism of Higher Education Enrolment Opportunities

Individual education performance is usually influenced jointly by ability and background (family background). The relative share of these two factors forms the basic grounds for judgments of educational equity. Using sheaf coefficients, we compare the influence of these two mechanisms on the distribution of access to regular first degree higher education opportunities for institutions at different levels. Our findings show that both ability and family background have a marked influence. The higher the level of the institution, the greater the ability demanded of its students. The effect of family also increases significantly at this level, but ability always has a much stronger influence than family background. It can be seen that though family background is influential in the distribution of higher education opportunities in China today, ability fundamentally remains the dominant criterion, embodying the classic features of a meritocratic society “open to talent.”