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11.
The problem considered is that of finding an optimum measurement schedule to estimate population parameters in a nonlinear model when the patient effects are random. The paper presents examples of the use of sensitivity functions, derived from the General Equivalence Theorem for D-optimality, in the construction of optimum population designs for such schedules. With independent observations, the theorem applies to the potential inclusion of a single observation. However, in population designs the observations are correlated and the theorem applies to the inclusion of an additional measurement schedule. In one example, three groups of patients of differing size are subject to distinct schedules. Numerical, as opposed to analytical, calculation of the sensitivity function is advocated. The required covariances of the observations are found by simulation. 相似文献
12.
Merging information for semiparametric density estimation 总被引:1,自引:0,他引:1
Konstantinos Fokianos 《Journal of the Royal Statistical Society. Series B, Statistical methodology》2004,66(4):941-958
Summary. The density ratio model specifies that the likelihood ratio of m −1 probability density functions with respect to the m th is of known parametric form without reference to any parametric model. We study the semiparametric inference problem that is related to the density ratio model by appealing to the methodology of empirical likelihood. The combined data from all the samples leads to more efficient kernel density estimators for the unknown distributions. We adopt variants of well-established techniques to choose the smoothing parameter for the density estimators proposed. 相似文献
13.
A Semi-parametric Regression Model with Errors in Variables 总被引:4,自引:0,他引:4
Abstract. In this paper, we consider a partial linear regression model with measurement errors in possibly all the variables. We use a method of moments and deconvolution to construct a new class of parametric estimators together with a non-parametric kernel estimator. Strong convergence, optimal rate of weak convergence and asymptotic normality of the estimators are investigated. 相似文献
14.
Gabriela Beganu 《Statistical Methods and Applications》2007,16(3):347-356
It is known that the Henderson Method III (Biometrics 9:226–252, 1953) is of special interest for the mixed linear models
because the estimators of the variance components are unaffected by the parameters of the fixed factor (or factors). This
article deals with generalizations and minor extensions of the results obtained for the univariate linear models. A MANOVA
mixed model is presented in a convenient form and the covariance components estimators are given on finite dimensional linear
spaces. The results use both the usual parametric representations and the coordinate-free approach of Kruskal (Ann Math Statist
39:70–75, 1968) and Eaton (Ann Math Statist 41:528–538, 1970). The normal equations are generalized and it is given a necessary
and sufficient condition for the existence of quadratic unbiased estimators for covariance components in the considered model. 相似文献
15.
针对串联型稳压器,设计了一种应用于串联型稳压器具有自建基准的新型误差放大电路。该电路具有构思巧妙,结构优化,易于集成及较高的开环增益,共模抑制比及交流特性的优点。通过验证,实测数据与仿真结果基本一致。 相似文献
16.
杨曼英 《湖南人文科技学院学报》2004,(2):78-79
通过定义、定理、正反对比的例题论述了函数列收敛、一致收敛、内闭一致收敛及其之间的关系与差异。 相似文献
17.
Peter Hall Qiwei Yao 《Journal of the Royal Statistical Society. Series B, Statistical methodology》2003,65(2):425-442
Summary. We develop a general methodology for tilting time series data. Attention is focused on a large class of regression problems, where errors are expressed through autoregressive processes. The class has a range of important applications and in the context of our work may be used to illustrate the application of tilting methods to interval estimation in regression, robust statistical inference and estimation subject to constraints. The method can be viewed as 'empirical likelihood with nuisance parameters'. 相似文献
18.
Diagnostics for dependence within time series extremes 总被引:1,自引:0,他引:1
Anthony W. Ledford Jonathan A. Tawn 《Journal of the Royal Statistical Society. Series B, Statistical methodology》2003,65(2):521-543
Summary. The analysis of extreme values within a stationary time series entails various assumptions concerning its long- and short-range dependence. We present a range of new diagnostic tools for assessing whether these assumptions are appropriate and for identifying structure within extreme events. These tools are based on tail characteristics of joint survivor functions but can be implemented by using existing estimation methods for extremes of univariate independent and identically distributed variables. Our diagnostic aids are illustrated through theoretical examples, simulation studies and by application to rainfall and exchange rate data. On the basis of these diagnostics we can explain characteristics that are found in the observed extreme events of these series and also gain insight into the properties of events that are more extreme than those observed. 相似文献
19.
Impacts of complex emergencies or relief interventions have often been evaluated by absolute mortality compared to international standardized mortality rates. A better evaluation would be to compare with local baseline mortality of the affected populations. A projection of population-based survival data into time of emergency or intervention based on information from before the emergency may create a local baseline reference. We find a log-transformed Gaussian time series model where standard errors of the estimated rates are included in the variance to have the best forecasting capacity. However, if time-at-risk during the forecasted period is known then forecasting might be done using a Poisson time series model with overdispersion. Whatever, the standard error of the estimated rates must be included in the variance of the model either in an additive form in a Gaussian model or in a multiplicative form by overdispersion in a Poisson model. Data on which the forecasting is based must be modelled carefully concerning not only calendar-time trends but also periods with excessive frequency of events (epidemics) and seasonal variations to eliminate residual autocorrelation and to make a proper reference for comparison, reflecting changes over time during the emergency. Hence, when modelled properly it is possible to predict a reference to an emergency-affected population based on local conditions. We predicted childhood mortality during the war in Guinea-Bissau 1998-1999. We found an increased mortality in the first half-year of the war and a mortality corresponding to the expected one in the last half-year of the war. 相似文献
20.