Functional principal component analysis via regularized Gaussian basis expansions and its application to unbalanced data

This paper introduces regularized functional principal component analysis for multidimensional functional data sets, utilizing Gaussian basis functions. An essential point in a functional approach via basis expansions is the evaluation of the matrix for the integral of the product of any two bases (cross-product matrix). Advantages of the use of the Gaussian type of basis functions in the functional approach are that its cross-product matrix can be easily calculated, and it creates a much more flexible instrument for transforming each individual's observation into a functional form. The proposed method is applied to the analysis of three-dimensional (3D) protein structural data that can be referred to as unbalanced data. It is shown that our method extracts useful information from unbalanced data through the application. Numerical experiments are conducted to investigate the effectiveness of our method via Gaussian basis functions, compared to the method based on B-splines. On performing regularized functional principal component analysis with B-splines, we also derive the exact form of its cross-product matrix. The numerical results show that our methodology is superior to the method based on B-splines for unbalanced data.     

大规模定制产品柔性分析

提出了一种表达大规模定制产品及其设计参数定制难易程度的指标———柔性指数。基于公理化设计理论,建立了定制方程,导出了柔性指数的计算方法。提出了一种通过计算直接影响设计参数数量和间接影响设计参数数量来比较柔性指数的简便方法。     

基于B-Z反应的企业系统协同演化模型

以典型的具有自组织特点的"B-z"反应模型为基础,应用分析复杂巨系统的协同学思想分析企业系统自组织演化规律.研究表明:利用复杂性科学方法解决经济系统不确定性问题的研究逐步增多,但大部分仍停留在定性描述或构建简单的2维变量模型模拟企业系统演化的阶段.通过引入"B-Z"反应模型可以构建3维变量模型进行企业系统定量描述,使其...     

A note on the equivariant estimation of an exponential scale using progressively censored data

We consider the problem of estimating the scale parameter θ$\theta$ of the shifted exponential distribution with unknown location based on a type II progressively censored sample. Under a large class of bowl-shaped loss functions, a smooth estimator, that dominates the minimum risk equivariant estimator of θ$\theta$, is proposed. A numerical study is performed and shows that the improved estimator yields significant risk reduction over the MRE.     

Semiparametric analysis for case-control studies: a partial smoothing spline approach

Case-control data are often used in medical-related applications, and most studies have applied parametric logistic regression to analyze such data. In this study, we investigated a semiparametric model for the analysis of case-control data by relaxing the linearity assumption of risk factors by using a partial smoothing spline model. A faster computation method for the model by extending the lower-dimensional approximation approach of Gu and Kim 4 Gu, C. and Kim, Y.-J. 2002. Penalized likelihood regression: General formulation and efficient approximation. Canad. J. Statist., 30: 619–628. [Crossref], [Web of Science ®] [Google Scholar] developed in penalized likelihood regression is considered to apply to case-control studies. Simulations were conducted to evaluate the performance of the method with selected smoothing parameters and to compare the method with existing methods. The method was applied to Korean gastric cancer case-control data to estimate the nonparametric probability function of age and regression parameters for other categorical risk factors simultaneously. The method could be used in preliminary studies to identify whether there is a flexible function form of risk factors in the semiparametric logistic regression analysis involving a large data set.     

Normalization of the origin-shifted exponential distribution for control chart construction

This study demonstrates that a location parameter of an exponential distribution significantly influences normalization of the exponential. The Kullback–Leibler information number is shown to be an appropriate index for measuring data normality using a location parameter. Control charts based on probability limits and transformation are compared for known and estimated location parameters. The probabilities of type II error (β-risks) and average run length (ARL) without a location parameter indicate an ability to detect an out-of-control signal of an individual chart using a power transformation similar to using probability limits. The β-risks and ARL of control charts with an estimated location parameter deviate significantly from their theoretical values when a small sample size of n≤50 is used. Therefore, without taking into account of the existence of a location parameter, the control charts result in inaccurate detection of an out-of-control signal regardless of whether a power or natural logarithmic transformation is used. The effects of a location parameter should be eliminated before transformation. Two examples are presented to illustrate these findings.     

Probability matching priors for an extended statistical calibration model

Statistical calibration or inverse prediction involves data collected in two stages. In the first stage, several values of an endogenous variable are observed, each corresponding to a known value of an exogenous variable; in the second stage, one or more values of the endogenous variable are observed which correspond to an unknown value of the exogenous variable. When estimating the value of the latter, it has been suggested that the variability about the regression relationship should not be assumed to be equal for the two stages of data collection. In this paper, the authors present a Bayesian method of analysis based on noninformative priors that takes this heteroscedasticity into account.     

Parameter estimation for a deformable template model

In recent years, a number of statistical models have been proposed for the purposes of high-level image analysis tasks such as object recognition. However, in general, these models remain hard to use in practice, partly as a result of their complexity, partly through lack of software. In this paper we concentrate on a particular deformable template model which has proved potentially useful for locating and labelling cells in microscope slides Rue and Hurn (1999). This model requires the specification of a number of rather non-intuitive parameters which control the shape variability of the deformed templates. Our goal is to arrange the estimation of these parameters in such a way that the microscope user's expertise is exploited to provide the necessary training data graphically by identifying a number of cells displayed on a computer screen, but that no additional statistical input is required. In this paper we use maximum likelihood estimation incorporating the error structure in the generation of our training data.     

空主语参数和汉语的无主句

文章在普遍语法的理论框架下讨论了汉语的无主句现象,指出:普遍语法中的参数并非总是两分的,非此即彼。空主语参数既不能直接证明汉语属于主语脱落的语言;通过将典型的非主语脱落语言作为参照物进行对比分析,汉语句子中的无主语现象也不符合空主语参数中非主语脱落的条件,而是显示出其自身的特殊性。     

A class of confidence intervals for sequential phase II clinical trials with binary outcome

The phase II clinical trials often use the binary outcome. Thus, accessing the success rate of the treatment is a primary objective for the phase II clinical trials. Reporting confidence intervals is a common practice for clinical trials. Due to the group sequence design and relatively small sample size, many existing confidence intervals for phase II trials are much conservative. In this paper, we propose a class of confidence intervals for binary outcomes. We also provide a general theory to assess the coverage of confidence intervals for discrete distributions, and hence make recommendations for choosing the parameter in calculating the confidence interval. The proposed method is applied to Simon's [14] optimal two-stage design with numerical studies. The proposed method can be viewed as an alternative approach for the confidence interval for discrete distributions in general.