Bayesian composite Tobit quantile regression

Composite quantile regression models have been shown to be effective techniques in improving the prediction accuracy [H. Zou and M. Yuan, Composite quantile regression and the oracle model selection theory, Ann. Statist. 36 (2008), pp. 1108–1126; J. Bradic, J. Fan, and W. Wang, Penalized composite quasi-likelihood for ultrahighdimensional variable selection, J. R. Stat. Soc. Ser. B 73 (2011), pp. 325–349; Z. Zhao and Z. Xiao, Efficient regressions via optimally combining quantile information, Econometric Theory 30(06) (2014), pp. 1272–1314]. This paper studies composite Tobit quantile regression (TQReg) from a Bayesian perspective. A simple and efficient MCMC-based computation method is derived for posterior inference using a mixture of an exponential and a scaled normal distribution of the skewed Laplace distribution. The approach is illustrated via simulation studies and a real data set. Results show that combine information across different quantiles can provide a useful method in efficient statistical estimation. This is the first work to discuss composite TQReg from a Bayesian perspective.     

Use of a historical control group in a noninferiority trial assessing a new antibacterial treatment: A case study and discussion of practical implementation aspects

When recruitment into a clinical trial is limited due to rarity of the disease of interest, or when recruitment to the control arm is limited due to ethical reasons (eg, pediatric studies or important unmet medical need), exploiting historical controls to augment the prospectively collected database can be an attractive option. Statistical methods for combining historical data with randomized data, while accounting for the incompatibility between the two, have been recently proposed and remain an active field of research. The current literature is lacking a rigorous comparison between methods but also guidelines about their use in practice. In this paper, we compare the existing methods based on a confirmatory phase III study design exercise done for a new antibacterial therapy with a binary endpoint and a single historical dataset. A procedure to assess the relative performance of the different methods for borrowing information from historical control data is proposed, and practical questions related to the selection and implementation of methods are discussed. Based on our examination, we found that the methods have a comparable performance, but we recommend the robust mixture prior for its ease of implementation.     

关于Gauss-Weierstrass算子线性组合的加权逼近

本文研究Gauss-Weierstrass算子的一类线性组合加Jacobi权的一致逼近问题，给出了逼近的正、逆定理和逼近阶的特征刻划。     

Reference priors for exponential families

Reference analysis, introduced by Bernardo (J. Roy. Statist. Soc. 41 (1979) 113) and further developed by Berger and Bernardo (On the development of reference priors (with discussion). In: J.M. Bernardo, J.O. Berger, A.P. Dawid, A.F.M. Smith (Eds.), Bayesian Statistics, Vol. 4, Clarendon Press, Oxford, pp. 35–60), has proved to be one of the most successful general methods to derive noninformative prior distributions. In practice, however, reference priors are typically difficult to obtain. In this paper we show how to find reference priors for a wide class of exponential family likelihoods.     

Bayesian methods for generalized linear models with covariates missing at random

The authors propose methods for Bayesian inference for generalized linear models with missing covariate data. They specify a parametric distribution for the covariates that is written as a sequence of one‐dimensional conditional distributions. They propose an informative class of joint prior distributions for the regression coefficients and the parameters arising from the covariate distributions. They examine the properties of the proposed prior and resulting posterior distributions. They also present a Bayesian criterion for comparing various models, and a calibration is derived for it. A detailed simulation is conducted and two real data sets are examined to demonstrate the methodology.     

Engaging Indigeneity in Development Policy

This article explores how development programming in rural poverty and the environment can work with indigenous peoples. It draws on research conducted in Asia and Latin America to suggest how indigeneity can be understood as specific kinds of marginalisation intersecting with self‐identification and recognition as indigenous. Current obstacles to effective engagement with indigenous peoples are outlined, and suggestions are offered for pro‐actively addressing their experience. Two critical areas where there are opportunities for donors to support indigenous peoples' priorities include ‘FPIC’ (Free Prior and Informed Consent) and a careful consideration of the implications of niche‐market engagement.     

A Bayesian method of sample size determination with practical applications

Summary.  The problem motivating the paper is the determination of sample size in clinical trials under normal likelihoods and at the substantive testing stage of a financial audit where normality is not an appropriate assumption. A combination of analytical and simulation-based techniques within the Bayesian framework is proposed. The framework accommodates two different prior distributions: one is the general purpose fitting prior distribution that is used in Bayesian analysis and the other is the expert subjective prior distribution, the sampling prior which is believed to generate the parameter values which in turn generate the data. We obtain many theoretical results and one key result is that typical non-informative prior distributions lead to very small sample sizes. In contrast, a very informative prior distribution may either lead to a very small or a very large sample size depending on the location of the centre of the prior distribution and the hypothesized value of the parameter. The methods that are developed are quite general and can be applied to other sample size determination problems. Some numerical illustrations which bring out many other aspects of the optimum sample size are given.     

Linear statistics in change-point estimation and their asymptotic behaviour

ABSTRACT The limiting behaviour of Bayes procedures in the asymptotic setting of the change-point estimation problem is studied. It is shown that the distribution of the difference between the Bayes estimator and the parameter converges to the distribution of a fairly complicated random variable. A class of linear statistics is introduced, and the form of the Bayes estimator within this class is deduced. The asymptotic properties of this linear estimator are investigated in two different settings for the prior distribution.     

Do bootstrap confidence procedures behave well uniformly in P?

An important statistical problem is to construct a confidence set for some functional T(P) of some unknown probability distribution P. Typically, this involves approximating the sampling distribution J_n(P) of some pivot based on a sample of size n from P. A bootstrap procedure is to estimate J_n(P) by J_n(&Pcirc;_n), where P?_n is the empirical measure based on a sample of size n from P. Typically, one has that J_n(P) and J_n(P?_n) are close in an appropriate sense. Two questions are addressed in this note. Are J_n(P) and J_n(P?_n) uniformly close as P varies as well? If so, do confidence statements about T(P) possess a corresponding uniformity property? In the case T(P) = P, the answer to the first questions is yes; the answer to the second is no. However, bootstrap confidence statements about T(P) can be made uniform over a restricted, though large, class of P. Similar results apply to other functional T(P).     

Conservative prior distributions for variance parameters in hierarchical models

Bayesian hierarchical models typically involve specifying prior distributions for one or more variance components. This is rather removed from the observed data, so specification based on expert knowledge can be difficult. While there are suggestions for “default” priors in the literature, often a conditionally conjugate inverse‐gamma specification is used, despite documented drawbacks of this choice. The authors suggest “conservative” prior distributions for variance components, which deliberately give more weight to smaller values. These are appropriate for investigators who are skeptical about the presence of variability in the second‐stage parameters (random effects) and want to particularly guard against inferring more structure than is really present. The suggested priors readily adapt to various hierarchical modelling settings, such as fitting smooth curves, modelling spatial variation and combining data from multiple sites.