Bayesian bridge-randomized penalized quantile regression estimation for linear regression model with AP(q) perturbation

Bridge penalized regression has many desirable statistical properties such as unbiasedness, sparseness as well as ‘oracle’. In Bayesian framework, bridge regularized penalty can be implemented based on generalized Gaussian distribution (GGD) prior. In this paper, we incorporate Bayesian bridge-randomized penalty and its adaptive version into the quantile regression (QR) models with autoregressive perturbations to conduct Bayesian penalization estimation. Employing the working likelihood of the asymmetric Laplace distribution (ALD) perturbations, the Bayesian joint hierarchical models are established. Based on the mixture representations of the ALD and generalized Gaussian distribution (GGD) priors of coefficients, the hybrid algorithms based on Gibbs sampler and Metropolis-Hasting sampler are provided to conduct fully Bayesian posterior estimation. Finally, the proposed Bayesian procedures are illustrated by some simulation examples and applied to a real data application of the electricity consumption.     

Bayesian sample size determination for phase IIA clinical trials using historical data and semi‐parametric prior's elicitation

The Simon's two‐stage design is the most commonly applied among multi‐stage designs in phase IIA clinical trials. It combines the sample sizes at the two stages in order to minimize either the expected or the maximum sample size. When the uncertainty about pre‐trial beliefs on the expected or desired response rate is high, a Bayesian alternative should be considered since it allows to deal with the entire distribution of the parameter of interest in a more natural way. In this setting, a crucial issue is how to construct a distribution from the available summaries to use as a clinical prior in a Bayesian design. In this work, we explore the Bayesian counterparts of the Simon's two‐stage design based on the predictive version of the single threshold design. This design requires specifying two prior distributions: the analysis prior, which is used to compute the posterior probabilities, and the design prior, which is employed to obtain the prior predictive distribution. While the usual approach is to build beta priors for carrying out a conjugate analysis, we derived both the analysis and the design distributions through linear combinations of B‐splines. The motivating example is the planning of the phase IIA two‐stage trial on anti‐HER2 DNA vaccine in breast cancer, where initial beliefs formed from elicited experts' opinions and historical data showed a high level of uncertainty. In a sample size determination problem, the impact of different priors is evaluated.     

Nonparametric Bayesian inference for multivariate density functions using Feller priors

Multivariate density estimation plays an important role in investigating the mechanism of high-dimensional data. This article describes a nonparametric Bayesian approach to the estimation of multivariate densities. A general procedure is proposed for constructing Feller priors for multivariate densities and their theoretical properties as nonparametric priors are established. A blocked Gibbs sampling algorithm is devised to sample from the posterior of the multivariate density. A simulation study is conducted to evaluate the performance of the procedure.     

On designing an acceptance sampling plan for the Pareto lifetime model

In this paper, the design of reliability sampling plans for the Pareto lifetime model under progressive Type-II right censoring is considered. Sampling plans are derived using the decision theoretic approach with a suitable loss or cost function that consists of sampling cost, rejection cost, and acceptance cost. The decision rule is based on the estimated reliability function. Plans are constructed within the Bayesian context using the natural conjugate prior. Simulations for evaluating the Bayes risk are carried out and the optimal sampling plans are reported for various sample sizes, observed number of failures and removal probabilities.     

A Bayesian approach to non-parametric monotone function estimation

Summary.  The paper proposes two Bayesian approaches to non-parametric monotone function estimation. The first approach uses a hierarchical Bayes framework and a characterization of smooth monotone functions given by Ramsay that allows unconstrained estimation. The second approach uses a Bayesian regression spline model of Smith and Kohn with a mixture distribution of constrained normal distributions as the prior for the regression coefficients to ensure the monotonicity of the resulting function estimate. The small sample properties of the two function estimators across a range of functions are provided via simulation and compared with existing methods. Asymptotic results are also given that show that Bayesian methods provide consistent function estimators for a large class of smooth functions. An example is provided involving economic demand functions that illustrates the application of the constrained regression spline estimator in the context of a multiple-regression model where two functions are constrained to be monotone.     

Prior elicitation in the classification problem

Results are developed concerning the asymptotic behaviour of the Bayes classification rule as the number of unclassified observations grows without bound. It is shown that unclassified observations serve only to estimate the individual population parameters in an unlabeled sense and do not provide information about the labels that are attached to the populations. Prior construction is approached through investigation of prior odds over regions of the joint parameter space (across all populations) deemed likely to contain the true joint parameter vector. It is shown that consideration of these prior odds can lead to more robust a posteriori classification of individual observations.     

Reference priors for a product of normal means when variances are unknown

The reference priors of Berger and Bernardo (1992) are derived for normal populations with unknown variances when the product of means is of interest. The priors are also shown to be Tibshirani's (1989) matching priors.     

Bayesian estimation for the Pareto income distribution

The Bayes estimators of the Gini index, the mean income and the proportion of the population living below a prescribed income level are obtained in this paper on the basis of censored income data from a pareto income distribution. The said estimators are obtained under the assumptions of a two-parameter exponential prior distribution and the usual squared error loss function. This work is also extended to the case when the income data are grouped and the exact incomes for the individuals in the population are not available. The method for the assessment of the hyperparameters is also outlined. Finally, the results are generalized for the doubly truncated gamma prior distribution. Now deceased.     

Uniform in Bandwidth Estimation of Integral Functionals of the Density Function

Abstract. We apply recent results on local U‐statistics to obtain uniform in bandwidth consistency and central limit theorems for some commonly used estimators of integral functionals of density functions.