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We study multiple-class classification problems. Both ordinal and categorical labeled cases are discussed. The common approaches for multiple-class classification are built on binary classifiers, in which one-versus-one and one-versus-rest are typical approaches. When the number of classes is large, then these binary-classifier-based methods may suffer from either computational costs or the highly imbalanced sample sizes in their training stage. In order to alleviate the computational burden and the imbalanced training data issue in multiple-class classification problems, we propose a method that has competitive performance and retains the ease of model interpretation, which is essential for a prognostic/predictive model.  相似文献   
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Objective: This study set out to assess effects of testosterone replacement therapy (TRT) on parameters of metabolic syndrome and vascular function in obese hypogonadal males with type 2 diabetes mellitus (DM2).

Study design: Fifty-five obese hypogonadal diabetic males on oral hypoglycemic treatment were enrolled into this one-year, double-blind, randomized, placebo-controlled clinical study. Group T (n?=?28) was treated with testosterone undecanoate (1000?mg i.m. every 10?weeks) while group P (n?=?27) received placebo.

Methods: Anthropometrical and vascular measurements – flow-mediated dilatation (FMD) and intima media thickness (IMT) – biochemical and hormonal blood sample analyses were performed at the start of the study and after one year. Derived parameters (BMI, HOMA-IR, calculated free testosterone (cFT) and bioavailable testosterone (BT)) were calculated.

Results: TRT resulted in reduction of HOMA-IR by 4.64?±?4.25 (p?p?p?=?.005).

Conclusion: TRT normalized serum testosterone levels, improved glycemic control and endothelial function while exerting no ill effects on the study population.  相似文献   
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Some of the main features of Bandura's self-efficacy concept are presented. The importance of the concept to the work organization and to individual performance is discussed. A field study is described. The first part of the study involved the development of parallel versions of a scale to assess managerial self-efficacy. Data concerning the psychometric properties of the parallel version of the scale show that they are reliable and independent of social desirability. The second part of the study provided evidence of the relationships between scores on the managerial self-efficacy scale and supervisors’ ratings of managers’ performance. The results indicate that managerial self-efficacy correlates with work performance ratings.  相似文献   
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In January 1981 a questionnaire was sent to 102 universities and colleges in Canada and the United States seeking information on enrolment in initial courses in statistics. That questionnaire has been analyzed and the results are presented in this paper.  相似文献   
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Using a sample consisting of 4,997 married couples from the National Survey of Families and Households, individual emotional distress, the occurrence of couple disagreements, couple fighting, and couple quality time together mediated the relationship between financial strain and personal assessments of marital instability. The overall results suggest that financial strain influences both positive and negative forms of couple interaction which are stronger mediators than personal emotional distress of the relationship between financial strain and marital instability. The results further suggest that there were no gender differences among these linkages.  相似文献   
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This paper reports a series of studies investigating the reliability and validity of the McMaster Family Assessment Device (FAD). The results indicated that the FAD has: (a) adequate test-retest reliability, (b) low correlations with social desirability, (c) moderate correlations with other self-report measures of family functioning, and (d) differentiates significantly between clinician-rated healthy and unhealthy families. Cut-off scores for identifying healthy and unhealthy families also were developed which have adequate sensitivity and specificity. Additionally, the relationships between the FAD, Family Unit Inventory, and FACES-II suggests that the cohension and adaptability scales from the FACES-II have a linear relationship with health/pathology.  相似文献   
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