Dietary and Inhalation Intake of Lead and Estimation of Blood Lead Levels in Adults and Children in Kanpur, India

This research was initiated to study lead levels in various food items in the city of Kanpur, India, to assess the dietary intake of lead and to estimate blood lead (PbB) levels, a biomarker of lead toxicity. For this purpose, sampling of food products, laboratory analysis, and computational exercises were undertaken. Specifically, six food groups (leafy vegetables, nonleafy vegetables, fruits, pulses, cereals, and milk), drinking water, and lead air concentration were considered for estimating lead intake. Results indicated highest lead content in leafy vegetables followed by pulses. Fruits showed low lead content and drinking water lead levels were always within tolerable limits. It was estimated that average daily lead intake through diet was about 114 microg/day for adults and 50 microg/day in children; tolerable limit is 250 microg/day for adults and 90 microg/day for children. The estimated lead intakes were translated into the resultant PbB concentrations for children and adults using a physiologically-based pharmacokinetic (PBPK) model. Monte Carlo simulation of PbB level variations for adults showed that probability of exceeding the tolerable limit of PbB (i.e.,10 microg/dL) was 0.062 for the pre-unleaded and 0.000328 for the post-unleaded gasoline period. The probability of exceeding tolerable limits in PbB level was reduced by a factor of 189 in the post-unleaded scenario. The study also suggested that in spite of the introduction of unleaded gasoline, children continue to be at a high risk (probability of exceeding 10 microg/dL = 0.39) because of a high intake of lead per unit body weight.     

Shortest paths among transient obstacles

Journal of Combinatorial Optimization - We present an optimal algorithm for determining a time-minimal rectilinear path among transient rectilinear obstacles. An obstacle is transient if it exists...     

Responses to globalization: Indian perspectives

India has a long tradition in influencing and participating to the globalization processes. Three phases can be distinguished in India’s history:

1. Colonial period up to 1947
2. Nation building through government policies from 1947 to 1990, and
3. The era of liberalization since 1991.

Like any ancient civilization, India has responded to the forces of globalization and has experienced both continuity and change. In the current phase, globalization is experiences a two-way scheme: while multinational companies are entering India, many Indian companies have a clear ambition to “take India to the world”. Given the number and diversity of Indian organizations, all approaches and interventions of OD have been already used. Family enterprises and the government have played a central role in shaping the Indian answer to globalization. Developing a global mindset is India’s major challenge for the future.