Psychological stress-factors and concentration of immunoglobulins and complement components in Norwegian nurses

Psychological stress produces immunological changes in animals, and increasing evidence suggests that this may also be true for humans. In the present study of 34 nurses in a busy ward of a Norwegian hospital, significant relationships have been demonstrated between die plasma levels of immunoglobulins and complement components and work-related 'stress', anxiety, and cognitive defence strategies. The main components of die work-related stress experience were role-stress and nonparticipation in decision-making.

The results indicate chat immunological parameters may perhaps be used as a psychological stress indicator, but the relationships are complex and can best be understood if individual coping and defence mechanisms are considered. Health symptoms were also examined, but these were not related to stress experience or immunological measures.     

Relations between environmental problems,psychology and health among shift-workers in the Norwegian process industry

Abstract

A group of 89 male shift-workers, mean age 38 years, was examined for health complaints, subjective experience of their work environment, psychological defence strategies, and immunological factors. They worked in a process industry, controlling a complex chemical process partly by instruments and partly by direct checking of mechanical devices such as valves. Shifts were eight hours long and changed every second week.

The main problem areas identified were problems with the management, colleagues and superiors, feelings of being under-valued, time pressure, fear of making mistakes, and lack of influence and communication. The main health complaints were sleep disturbance and gastro-intestinal problems. Shift workers also complained about allergies, breathing difficulties, tension, anxiety and depression. There were no pathological levels of plasma immunoglobulins (Ig) or Ig complements. However, levels did correlate with experience of work-related problems and with measures of defence mechanisms. Up to 25% of the variance in die immunological indicators was explained by a combination of defence mechanism scores and those of perceived health and work problems. This suggests that immunoglobulins may be an indicator of work-related health risks (‘stress’), even if the level of explained variance is too low to use immunoglobulins alone as a ‘marker’. The same variables, and immunoglobulins, also related significantly to perceived health. This may be a particularly important indicator, and when combined with immunology and psychological variables, also as a risk factor for organic disease.