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This research proposes a multi-criteria decision-making (MCDM) framework and demonstrates the impact of competitive conditions on supplier evaluation process for construction supply chains. The paper focuses on the supply chain of a large-scale housing project in order to illustrate the role of competitive capability and suppliers’ profile and its influence on supplier evaluation based on prevailing supply/market conditions. Various scenarios are investigated to demonstrate the impact of competition on supplier evaluation. The contribution of the study lies in highlighting the impact of supply/market conditions on MCDM decisions causing supplier evaluation ‘imbalance’ and MCDM usage. It is expected that the study will be useful for project management, construction, supply chain management, sourcing professionals. The findings of the study are generalisable to projects-based situations such as petroleum refinery and ship building where bill of materials typically consists of thousands of items and a large number of suppliers are involved.  相似文献   
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Background: Late-onset hypogonadism (LOH) presents with low serum testosterone (TT) levels and sexual and nonsexual symptoms. Erectile dysfunction affects a man’s self-esteem and as a result partner relationship and quality of life.

Objectives: To investigate the andrological clinical profile outcomes of testosterone therapy (TTh) in men (n?=?88) with symptomatic LOH complaints and symptoms.

Main outcome measures: Erectile function was assessed using the International Index of Erectile Function-5 questionnaire at baseline and at 6 and 12 months of TTh. In addition, penile length was measured at baseline and 12 months. We also evaluated nocturnal penile tumescence (NPT, using RigiScan) and blood flow of cavernous arteries (penile Doppler ultrasonography) at baseline and 12 months of TT.

Materials and methods: Eighty-eight LOH men (Mage 51.1 years) with erectile dysfunction, all with serum TT?<10.4?nmol/L before TTh. Patients received intramuscular long-acting testosterone undecanoate for 12 months.

Results: Following TTh, in all patients, serum TT levels were restored within 3 months to normal levels. Compared with baseline values, erectile function significantly improved at 6 (mean score increase 1.95) and 12 months (mean score increase 2.16). No significant changes in penile length were observed. NPT significantly improved at 12 months in terms of both the frequency (mean increase 1.27 times) and duration of rigidity (mean increase 5.12?min). As regards the blood flow of the cavernous arteries, we observed a significant improvement (decrease of 1.16?cm/s) and end diastolic velocity of the penile arteries.

Conclusion: TTh in men with LOH resulted in improvement of the erectile function, NPT, and to some extent the blood flow of the cavernous arteries.  相似文献   
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Many energy technologies that can provide reliable, low-carbon electricity generation are confined to nations that have access to robust technical and economic capabilities, either on their own or through geopolitical alliances. Equally important, these nations maintain a degree of institutional capacity that could lower the risks associated with deploying emergent energy technologies such as advanced nuclear or carbon capture and storage. The complexity, expense, and scrutiny that come with building these facilities make them infeasible choices for most nations. This paradigm is slowly changing, as the pressing need for low-carbon electricity generation and ongoing efforts to develop modular nuclear and carbon capture technologies have opened the door for potentially wider markets, including in nations without substantial institutional capacity. Here, using advanced nuclear technologies as our testbed, we develop new methods to evaluate national readiness for deploying complex energy infrastructure. Specifically, we use Data Envelopment Analysis—a method that eliminates the need for expert judgment—to benchmark performance across nations. We find that approximately 80% of new nuclear deployment occurs in nations that are in the top two quartiles of institutional and economic performance. However, 85% of potential low-carbon electricity demand growth is in nations that are in the bottom two quartiles of performance. We offer iconic paradigms for deploying nuclear power in each of these clusters of nations if the goal is to mitigate risk. Our research helps redouble efforts by industry, regulators, and international development agencies to focus on areas where readiness is low and risk correspondingly higher.  相似文献   
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This article challenges the idea that social media protest mobilization and communication are primarily propelled by the self-motivated sharing of ideas, plans, images, and resources. It shows that leadership plays a vital role in steering popular contention on key social platforms. This argument is developed through a detailed case study on the interaction between the administrators and users of the Kullena Khaled Said Facebook page, the most popular online platform during the Egyptian revolution of early 2011. The analysis specifically focuses on the period from 1 January until 15 February 2011. It draws from 1629 admin posts and 1,465,696 user comments, extracted via a customized version of Netvizz. For each day during this period, the three most engaged with posts, as well as the 10 most engaged with comments, have been translated and coded, making it possible to systematically examine how the administrators tried to shape the communication on the page, and how users responded to these efforts. This analysis is pursued from a sociotechnical perspective. It traces how the exchanges on the page are simultaneously shaped by the admins’ marketing strategies and the technological architecture of the Facebook page. On the basis of this exploration, we argue that the page administrators should be understood as ‘connective leaders’. Rather than directing protest activity through formal organizations and collective identity frames, as social movement leaders have traditionally done, connective leaders invite and steer user participation by employing sophisticated marketing strategies to connect users in online communication streams and networks.  相似文献   
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It is hard to see how our energy system can be decarbonized if the world abandons nuclear power, but equally hard to introduce the technology in nonnuclear energy states. This is especially true in countries with limited technical, institutional, and regulatory capabilities, where safety and proliferation concerns are acute. Given the need to achieve serious emissions mitigation by mid‐century, and the multidecadal effort required to develop robust nuclear governance institutions, we must look to other models that might facilitate nuclear plant deployment while mitigating the technology's risks. One such deployment paradigm is the build‐own‐operate‐return model. Because returning small land‐based reactors containing spent fuel is infeasible, we evaluate the cost, safety, and proliferation risks of a system in which small modular reactors are manufactured in a factory, and then deployed to a customer nation on a floating platform. This floating small modular reactor would be owned and operated by a single entity and returned unopened to the developed state for refueling. We developed a decision model that allows for a comparison of floating and land‐based alternatives considering key International Atomic Energy Agency plant‐siting criteria. Abandoning onsite refueling is beneficial, and floating reactors built in a central facility can potentially reduce the risk of cost overruns and the consequences of accidents. However, if the floating platform must be built to military‐grade specifications, then the cost would be much higher than a land‐based system. The analysis tool presented is flexible, and can assist planners in determining the scope of risks and uncertainty associated with different deployment options.  相似文献   
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Social Indicators Research - Based on the nationally representative micro-level dataset, the present paper investigates the prevalence of education-job mismatches and their effects on individual...  相似文献   
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Background and objectives: Diabetes mellitus is an important risk factor for erectile dysfunction (ED). Penile prosthesis implantation surgery is the final solution for diabetic patients with ED, but infections thereof are still a serious risk factor. While some studies suggest that most infections associated with penile prosthesis implantation are associated to high glycated hemoglobin (HbA1c) levels, other research did support such relationship.

Materials and methods: The current study assessed retrospectively, the association between HbA1c level and penile prosthesis surgery infection. We retrieved and reviewed the records of 300 diabetic patients who had penile prosthesis surgery at our Institution (January 2012–November 2016). Patients’ mean age was 55.26?±?10.9 years (31% patients were <50 years of age), and mean HbA1c was 7.60?±?1.90%.

Results: Infection rate among diabetics was 0.67%. Prevalence of prosthesis infection among patients with HbA1c?≤?9% was 0.9%, compared with 0% among patients with HbA1c?>?9%. Prosthesis infection risk did not significantly increase with higher HbA1c levels, with no meaningful difference in the median or mean level of HbA1c in the infected and non-infected diabetic patients.

Conclusion: Findings do not support the use of HbA1c values among diabetic patients who are candidates for penile prosthesis implantation surgery in order to identify and exclude those who might be prone to increased risk of prosthesis infections. Future studies would benefit from larger sample sizes in order to support or refute our findings.  相似文献   
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