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1.
Low dose risk estimation via simultaneous statistical inferences   总被引:2,自引:0,他引:2  
Summary.  The paper develops and studies simultaneous confidence bounds that are useful for making low dose inferences in quantitative risk analysis. Application is intended for risk assessment studies where human, animal or ecological data are used to set safe low dose levels of a toxic agent, but where study information is limited to high dose levels of the agent. Methods are derived for estimating simultaneous, one-sided, upper confidence limits on risk for end points measured on a continuous scale. From the simultaneous confidence bounds, lower confidence limits on the dose that is associated with a particular risk (often referred to as a bench-mark dose ) are calculated. An important feature of the simultaneous construction is that any inferences that are based on inverting the simultaneous confidence bounds apply automatically to inverse bounds on the bench-mark dose.  相似文献   
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In recent years there has been much debate about the impact of social class on individual behaviour, including personal consumption. The object of this study is to examine the degree of variation in consumption patterns between social classes in Finland in 1985 and to compare this with an analysis of data for 1955. The results indicate that socio-economic group was rather less significant when it came to differentiating consumption patterns in main expenditure categories, like housing, for the later point in time than it had been for the earlier one. In other words, the relative explanatory power of socio-economic group (and income group) has decreased in comparison with life-cycle variables (type of household and age of head of household). This suggest that differences in consumption expenditure patterns are no longer so heavily dependent on social class or economic resources but instead on the life cycle or way of life. However, this process is not comprehensive because, for example, the relative impact of social class on cultural consumption has increased.  相似文献   
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We discuss the issue of using benchmark doses for quantifying (excess) risk associated with exposure to environmental hazards. The paradigm of low-dose risk estimation in dose-response modeling is used as the primary application scenario. Emphasis is placed on making simultaneous inferences on benchmark doses when data are in the form of proportions, although the concepts translate easily to other forms of outcome data.  相似文献   
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Since 1965 hundreds of articles and books have been published about African American families. Nevertheless, our understanding of these families continues to be limited. There is a tendency to gloss over important within-group differences; thus, monolithic, stereotypic and inaccurance portrayals of Black family life are common. This paper sets aside debates of Black family pathology or viability, focusing instead on these families' essential character. The paper seeks to understand Black families on their own terms, locating them in relevant social, historical, political and cultural contexts. Key empirical patterns and trends reveal dramatic changes in Black family geographic location, headship, quality of life and socioeconomic status since 1950.A complex picture is revealed. There has been gradual but steady overall improvement alongside persistent, extreme racial disparties and pronounced class disparities among Black families. The proposed Black Family Socio-Ecological Context model specifies and connects institutional, interpersonal, environmental, temporal and cultural facts that shape the essential character of Black family life in such a way as to produce characteristics simultaneously shared and idiosyncratic. The model also provides an organized, systematic accounting of research and public policy issues relevant to the study of African American families.An early version co-authored with Richard A. English was presented during the National Council on Family Relations Meetings in Portland, Oregon, October 1980.  相似文献   
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Responses to the Adult Career Concerns Inventory (ACCI: Super, Thompson, Lindeman, Myers, & Jordaan, 1988) were organized through cluster analysis to identify different ways in which adults use exploratory behavior to cope with career development tasks. Significant differences in life-role salience among the types of adult career explorers identified were also investigated. Findings indicated a variety of ways in which adults use exploratory behavior. However, no significant differences were found in life-role salience among the types of career explorers. The discussion explains how career counselors can interpret their clients' ACCI profiles to select appropriate career interventions.  相似文献   
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In this study, we investigated whether incorporating eye tracking into cognitive interviewing is effective when pretesting survey questions. In the control condition, a cognitive interview was conducted using a standardized interview protocol that included pre-defined probing questions for about one-quarter of the questions in a 52-item questionnaire. In the experimental condition, participants’ eye movements were tracked while they completed an online version of the questionnaire. Simultaneously, their reading patterns were monitored for evidence of response problems. Afterward, a cognitive interview was conducted using an interview protocol identical to that in the control condition. We compared both approaches with regard to the number and types of problems they detected. We found support for our hypothesis that cognitive interviewing and eye tracking complement each other effectively. As expected, the hybrid method was more productive in identifying both questionnaire problems and problematic questions than applying cognitive interviewing alone.  相似文献   
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In this article, we propose a general method for testing the Granger noncausality hypothesis in stationary nonlinear models of unknown functional form. These tests are based on a Taylor expansion of the nonlinear model around a given point in the sample space. We study the performance of our tests by a Monte Carlo experiment and compare these to the most widely used linear test. Our tests appear to be well-sized and have reasonably good power properties.  相似文献   
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