Nested exposure case-control sampling: a sampling scheme to analyze rare time-dependent exposures

For large cohort studies with rare outcomes, the nested case-control design only requires data collection of small subsets of the individuals at risk. These are typically randomly sampled at the observed event times and a weighted, stratified analysis takes over the role of the full cohort analysis. Motivated by observational studies on the impact of hospital-acquired infection on hospital stay outcome, we are interested in situations, where not necessarily the outcome is rare, but time-dependent exposure such as the occurrence of an adverse event or disease progression is. Using the counting process formulation of general nested case-control designs, we propose three sampling schemes where not all commonly observed outcomes need to be included in the analysis. Rather, inclusion probabilities may be time-dependent and may even depend on the past sampling and exposure history. A bootstrap analysis of a full cohort data set from hospital epidemiology allows us to investigate the practical utility of the proposed sampling schemes in comparison to a full cohort analysis and a too simple application of the nested case-control design, if the outcome is not rare.

     

The Abject Embodiment of Cancer Patients: Dignity,Selfhood, and the Grotesque Body

The body is the empirical quintessence of the self. Because selfhood is symbolic, embodiment represents the personification and materialization of otherwise invisible qualities of personhood. The body and experiences of embodiment are central to our sense of being, who we think we are, and what others attribute to us. What happens, then, when one's body is humiliating? How does the self handle the implications of a gruesome body? How do people manage selfhood in light of grotesque physical appearances? This study explores these questions in the experiences of dying cancer patients and seeks to better understand relationships among body, self, and situated social interaction.     

Form Perception of Partly Occluded Shapes in 4‐Month‐Old Infants

Two habituation experiments were conducted to investigate how 4‐month‐old infants perceive partly occluded shapes. In the first experiment, we presented a simple, partly occluded shape to the infants until habituation was reached. Then we showed either a probable completion (one that would be predicted on the basis of both local and global cues) or an improbable completion. Longer looking times were found for the improbably completed shape (compared to probable and control conditions), suggesting that the probable shape was perceived during partial occlusion. In the second experiment, infants were habituated to more ambiguous partly occluded shapes, where local and global cues would result in different completions. For adults, the percept of these shapes is usually dominated by global influences. However, after habituation the infants looked longer at the globally completed shapes. These results suggest that by the age of 4 months, infants are able to infer the perceptual completion of partly occluded shapes, but for more ambiguous shapes, this completion seems to be dominated by local influences.     

No wonder social workers feel uncomfortable in court

The present article assesses the adversary systemper se and asks the question, Is there any place for courtroom antics and histrionics in cases involving children? Social workers are uncomfortable before the august body of thecourt, not because of any lack of education or knowledge on their part but because of the nature of the adversary process itself.     

Libertarian collective decision-making: A new framework

A model of collective decision-making is presented which enables us to analyze the allocation of individual rights and liberties. The model broadens the traditional social choice framework. In social choice theory it is usually assumed that individuals have preferences over a set of feasible alternatives and that society reaches a decision on the basis of those preferences only. In the model presented in this paper, decision procedures do not only take information about individual preferences as input, but also information about individual freedom. The specific decision procedures we present and analyze can be characterized as libertarian.This paper was written while I was a visitor at the University of California, Riverside. The visit was made possible by financial support of the Netherlands Organization of Scientific Research (NWO). I am extremely grateful to Prasanta Pattanaik for many stimulating discussions on the subject. For helpful comments I also thank Ad van Deemen, Grahame Lock, Huib Pellikaan and Marcel Wissenburg. Finally, I express my thanks to Wulf Gaertner and two anonymous referees.     

ETHNIC PLACES, POSTMODERNISM, AND URBAN CHANGE IN HOUSTON

City managers and urban sociologists traditionally viewed ethnic places as undesirable areas of overcrowding and social pathology. Regarded as either transitional districts or obstacles to modernization, ethnic places were subject to slum clearance during the modernist phase of urban development. Ethnic places have acquired a new historical and sentimental salience in the "postmodern" developmental era. Preservationist activists and minority "place entrepreneurs" project ethnic culture and symbolic representations in defensive or proactive ways to stimulate neighborhood revitalization. These trends are evident in the recent urban developmental history of Houston, Texas.