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ZW Kmietowicz  AD Pearman 《Omega》1984,12(4):391-399
The paper deals with decision making under conditions of linear partial information, i.e. when probabilities of states of nature are not known precisely, but are subject to linear constraints. Conditions ensuring strict and weak statistical dominance of one strategy over another are derived. It is also shown that weak dominance in terms of payoffs is equivalent to weak dominance in terms of regrets. The new results are more general than those obtained by Fishburn and by Kmietowicz and Pearman for weak and strict ranking of probabilities, and include them as special cases. The new results can be employed in practical decision making in several ways.  相似文献   
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Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) age-related withdrawal is very likely to be involved in the aging process and the onset of age-related diseases, giving rise to the question of whether preventing or compensating the decline of these steroids may have endocrine and clinical benefits. The aim of the present trial was to evaluate the endocrine, neuroendocrine and clinical consequences of a long-term (1 year), low-dose (25?mg/day) replacement therapy in a group of aging men who presented the clinical characteristics of partial androgen deficiency (PADAM). Circulating DHEA, DHEAS, androstenedione, total testosterone and free testosterone, dihydrotestosterone (DHT), progesterone, 17-hydroxyprogesterone, allopregnanolone, estrone, estradiol, sex hormone binding globulin (SHBG), cortisol, follicle stimulating hormone (FSH), luteinizing hormone (LH), growth hormone (GH) and insulin-like growth factor 1 (IGF-1) levels were evaluated monthly to assess the endocrine effects of the therapy, while β-endorphin values were used as a marker of the neuroendocrine effects. A Kupperman questionnaire was performed to evaluate the subjective symptoms before and after treatment.

The results showed a great modification of the endocrine profile; with the exception of cortisol levels, which remained unchanged, DHEA, DHEAS, androstenedione, total and free testosterone, DHT, progesterone, 17-hydroxyprogesterone, estrone, estradiol, GH, IGF-1 and β-endorphin levels increased significantly with respect to baseline values, while FSH, LH and SHBG levels showed a significant decrease. The Kupperman score indicated a progressive improvement in mood, fatigue and joint pain.

In conclusion, the present study demonstrates that 25?mg/day of DHEA is able to cause significant changes in the hormonal profile and clinical symptoms and can counteract the age-related decline of endocrine and neuroendocrine functions. Restoring DHEA levels to young adult values seems to benefit the age-related decline in physiological functions but, however promising, placebo-controlled trials are required to confirm these preliminary results.  相似文献   
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Time use studies are routinely used to comment on the distribution of labour between adults. More recently considerations of concurrent (or secondary) activities have been used to highlight the full social extent of childcare, and to show that mothers work disproportionately long hours. This paper addresses a blind spot in such studies: the domestic usefulness – or otherwise – of teenage children. It examines how measurements of secondary activities in Australian time use surveys contribute to understanding of the division of household, caring and total productive work between parents and teenagers. In this way the paper addresses a recent call by youth studies scholars to ‘bring the family back into focus‘. We found that secondary activities accentuate already inequitable division of labour between mothers, fathers, daughters and sons. However, the results were not uniform, and show that a minority of teenagers shoulder substantial domestic responsibilities. The paper concludes by arguing that teenagers need to be included, conceptually as well as practically, in considerations of sustainable and equitable divisions of household and caring work.  相似文献   
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