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The paper deals with the problem of using contours as the basis for defining probability distributions. First, the most general probability densities with given contours are obtained and the particular cases of circular and elliptical contours are dealt with. It is shown that the so-called elliptically contoured distributions do not include all possible cases. Next, the case of contours defined by polar coordinates is analyzed including its simulation and parameter estimation. Finally, the case of cumulative distribution functions with given contours is discussed. Several examples are used for illustrative purposes.  相似文献   
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In this paper, the task of determining expected values of sample moments, where the sample members have been selected based on noisy information, is considered. This task is a recurring problem in the theory of evolution strategies. Exact expressions for expected values of sums of products of concomitants of selected order statistics are derived. Then, using Edgeworth and Cornish-Fisher approximations, explicit results that depend on coefficients that can be determined numerically are obtained. While the results are exact only for normal populations, it is shown experimentally that including skewness and kurtosis in the calculations can yield greatly improved results for other distributions.  相似文献   
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Ten days after the Symbionese Liberation Army's shoot out in Los Angeles in 1974, the Cedars-Sinai Medical Center, Department of Family Child Psychiatry, Thalians Community Mental Health Center, sent a crisis team of three psychotherapists to a school in the black community. The psychotherapists used an art therapy approach with a third grade classroom of 21 black children. The team's procedure helped the children ventilate their reactions to a frightening event which occurred in their neighborhood. This paper describes the art therapy techniques which were utilized, the children's vivid pictorial and verbal expressions accompanied by the psychological aspects of their responses.  相似文献   
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"The study compares determinants of internal and international migration intentions, drawing upon interview data from a sample of adults in Ilocos Norte, a largely rural province in the Philippines. A regression model is applied to test the relative determinants of intentions to migrate to Manila and to Hawaii. The study is based on a value-expectancy model of migration decision making. The results document the importance of subjective expectations related to the attainment of different values and goals in Manila and Hawaii."  相似文献   
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Differences in patient characteristics, including age, sex, and race influence the safety and effectiveness of drugs, biologic products, and medical devices. Here we provide a summary of the topics discussed during the opening panel at the 2018 Johns Hopkins Center for Excellence in Regulatory Science and Innovation symposium on Assessing and Communicating Heterogeneity of Treatment Effects for Patient Subpopulations: Challenges and Opportunities. The goal of this session was to provide a brief overview of FDA-regulated therapeutics, including drugs, biologics and medical devices, and some of the major sources of heterogeneity of treatment effects (HTE) related to patient demographics, such as age, sex and race. The panel discussed the US Food and Drug Administration's role in reviewing and regulating drugs, devices, and biologic products and the challenges associated with ensuring that diverse patient populations benefit from these therapeutics. Ultimately, ensuring diverse demographic inclusion in clinical trials, and designing basic and clinical research studies to account for the intended patient population's age, sex, race, and genetic factors among other characteristics, will lead to better, safer therapies for diverse patient populations.  相似文献   
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This article examines poverty and welfare provision in early twentieth-century Beijing as dialogue and transaction between the city government and the urban poor. Earlier studies of the Chinese urban have tended to emphasize the material aspects of urban development, and the efforts of planners and city governments to modernize China’s cities, rather than the human experience of the city. This article draws on the extensive archives of the Beijing Municipal Government Social Affairs Bureau to extend our understanding of the experience of poverty and the agency of the poor. The archive confirms that Beijing’s growing and increasingly formalized welfare institutions were designed to discipline the poor as they alleviated poverty. However, the correspondence between applicants for welfare and the Social Affairs Bureau also reveals that the poor often approached these institutions instrumentally and assertively. Recourse to the welfare institute became a livelihood tactic, a claim on the authorities in pursuit of which certain sub-groups within the poor mobilized intangible assets, from social networks to understanding of the intended terms of the system, to sway the terms of their engagement with the authorities in their own favour.  相似文献   
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