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In recent years, European pharmaceutical regulators have increasingly committed to heightening access to raw safety‐related data as part of a wave of transparency initiatives (e.g., providing public Internet‐mediated access to clinical trials data). Yet, the regulators—who are under significant pressure—have not yet benefited from a systematic review of this new policy. In seeking to inject much needed evidence, this article explores the effects of new transparency policies designed to promote meaningful communication of risks and benefits to patients. Results of a cross‐national European survey with respondents from Great Britain, the Netherlands, Spain, France, Germany, and Sweden (N = 5,648) shed light on how patients and the public are likely to react to the regulators’ new transparency policies. The findings demonstrate clear national variations in how European citizens are likely to react and emphasize the need to develop evidence‐based, reasoned transparency policies that integrate benefit‐risk communication. The authors conclude by providing six specific recommendations, informed by the study, that seek to improve the European transparency model both within the medical field and across health, safety, and environmental policy domains. 相似文献
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Findings are presented from an ecologically grounded, longitudinal study of 206 urban, ethnic minority adolescents that used hierarchical linear modeling to examine: (1) individual trajectories of change in adolescents' perceptions of general and closest same‐sex friendship quality from middle to late adolescence; (2) the effects of gender and ethnicity on these trajectories of change; and (3) the relative influence of adolescents' perceptions of individual‐level (i.e., self‐esteem) and contextual‐level (i.e., family relationships and school climate) variables on change over time in perceptions of friendship quality. Findings indicated that adolescents' perceptions of the quality of friendships improved from middle to late adolescence. Boys reported sharper increases over time than girls in their perceptions of the quality of their closest, same‐sex friendships. Furthermore, perceptions of contextual level variables (i.e., family relationships, teacher/student relations, and student/student relations) were significantly associated with change over time in perceptions of general and/or closest same‐sex friendship quality. 相似文献
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Li Way Lee 《Economic inquiry》1980,18(4):617-630
The three uses of one's time — leisure, nonmarket work, and market work — are affected by the availability of others' time for sale in the market. The paper integrates the supply of time and the demand for others' time by means of geometric models of exchange and production. Possible patterns of market work behavior are enriched by the incorporation of proportional and lump-sum transaction costs. The diversity of the results argues against indiscriminate reliance on institutional restrictions in explaining work decisions. 相似文献
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This study examined vicarious trauma effects in male and female clinicians who treat sexual abuse survivors (n = 111) and sexual offenders (n = 272). The national survey was conducted using a random sample of clinical members of two professional organizations. Analyses tested the relationships between demographic variables, maltreatment history, client population served, and cognitions about trust of and intimacy with others, using the Trauma Stress Institute Belief Scale (TSIBS-R-L, Pearlman 2003), the Childhood Trauma Questionnaire (CTQ, Bernstein & Fink, 1998), and author-generated questions. Respondents reported high rates of multiple forms of childhood maltreatment; however there was no relationship between history of child sexual abuse and vicarious trauma effects. Scores for self-reported disruption in cognitions about intimacy with others exceeded norms for mental health professionals. Sequential regression analyses were used to examine theoretically-derived variables. Implications for practice and research are detailed. 相似文献
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Doug Way 《Serials Review》2013,39(4):214-220
AbstractGrand Valley State University Libraries implemented Serials Solutions' web-scale discovery tool, Summon, during the fall of 2009. This case study explores whether Summon had an impact on the use of the library's resources during its first semester of implementation. An examination of usage statistics showed a dramatic decrease in the use of traditional abstracting and indexing databases and an equally dramatic increase in the use of full-text resources from full-text database and online journal collections. The author concludes that the increase in full-text use is linked to the implementation of a web-scale discovery tool. 相似文献
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Li Way Lee 《Journal of Socio》2010,39(2):204-208
Expected-utility theory can explain why people who are terminally ill often feel a surge in wellbeing and hope to live longer when they have the option of legally ending their lives. Behavioral theories, however, may better answer larger questions such as why so few terminally-ill people bother to get that option. 相似文献
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The current study presents a growth curve analysis of self‐esteem among Black, Latino, and Asian American high school students. A series of hierarchical linear models were used to examine patterns and predictors of change in self‐esteem over time. Results revealed an average increase in self‐esteem with age. Although boys and girls experienced similar trajectories of self‐esteem, ethnicity was a significant moderator of developmental change. Black adolescents reported higher self‐esteem, while Asian American adolescents reported lower self‐esteem, compared with their Latino peers. Latino adolescents experienced a sharper increase in self‐esteem over time compared with Black adolescents. The unique and conjoint effects of adolescents' experiences with peers, family, and school were examined in relation to self‐esteem trajectories. Results revealed that each perceived context was significantly associated with self‐esteem trajectories when examined independently, but family experiences emerged as most strongly related to changes in self‐esteem. Results underscore the need to examine change at the individual level, as well as the importance of studying the unique and conjoint effects of individual and contextual‐level variables on developmental processes among ethnic minority adolescents. 相似文献
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The spread of HIV infection and the subsequent AIDS morbidity and mortality threatens to have a substantial impact on societies in subSaharan Africa. Infection levels are increasing rapidly in many regions, especially in urban areas. The consequences of high levels of infection are inescapable, although, due to the long incubation period, morbidity and mortality increases lag several years behind increases in infection levels. The impact of a serious AIDS epidemic will be felt by many sectors of the society. Mortality levels will substantially increase, especially among newborns and adults under age 50. This mortality will remove many productive members from the economy, while HIV-related illness will reduce the productivity of the infected population. Health care facilities will be severely strained to bear the increases in hospitalized populations. Those without access to the formal health care system will rely on family members for support and care. 相似文献