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1.
Estimated associations between an outcome variable and misclassified covariates tend to be biased when the methods of estimation that ignore the classification error are applied. Available methods to account for misclassification often require the use of a validation sample (i.e. a gold standard). In practice, however, such a gold standard may be unavailable or impractical. We propose a Bayesian approach to adjust for misclassification in a binary covariate in the random effect logistic model when a gold standard is not available. This Markov Chain Monte Carlo (MCMC) approach uses two imperfect measures of a dichotomous exposure under the assumptions of conditional independence and non-differential misclassification. A simulated numerical example and a real clinical example are given to illustrate the proposed approach. Our results suggest that the estimated log odds of inpatient care and the corresponding standard deviation are much larger in our proposed method compared with the models ignoring misclassification. Ignoring misclassification produces downwardly biased estimates and underestimate uncertainty.  相似文献   
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This article provides an overview of social trust, examining its various aspects and components. Trust is best understood in a sociological sense by focusing on its important relational characteristic. Following this lead, the article discusses briefly how social trust relates to social capital and examines factors that shape the development of social trust, along with outcomes related to variations in trust, classifying them by analytical level (i.e., individual, community, group, organizational, and societal). The article concludes by assessing the strengths and weaknesses of existing research and by identifying some important questions that have not yet been adequately addressed.  相似文献   
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A Lotto Systems bet allows the player to nominate n numbers from which (s)he believes the winning six numbers will be drawn, and to bet on all combinations of six of these n numbers. Assume that the winning six numbers come from the nominated n. How many combinations must be entered to guarantee that one combination will include at least five of the winning six numbers? The problem is generalized in this paper, and the method of simulated annealing is used to find solutions for various situations. The case where two supplementary numbers are drawn after the initial six winning numbers is also considered.  相似文献   
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Adolescence is often assumed to be the most important period of life for understanding teen childbearing risk. Developmental perspectives challenge that assumption, offering the possibility that early childhood characteristics may have unique and lasting effects on the risk for teen childbearing. This study examined family life risk factors (socioeconomic status, family stress, and parental involvement in education) and how their effects on teen childbearing risk varied, depending on the childhood age at which they were experienced. Prospective life history data from the National Child Development Study of Great Britain were used to study a birth cohort of 4,928 British women, 15.3% of who became pregnant as teens. This study demonstrated that data from early childhood significantly contribute to the understanding of teen childbearing risk.  相似文献   
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Russia’s role in ‘animation’ of the Kyoto Protocol was crucial. Its initial vacillation on ratification was predominantly due to political bargaining with the EU. Domestic economic rationales [i.e. impacts of emission trading and Joint Implementation (JI) projects] were important to a much lesser extent and environmental motives did not seem to play any role in the decision. Since the Protocol entered into force, there have been significant delays in complete establishment of policy implementation frameworks, which are necessary for Russia to start benefiting from JI and emission trading. Only recently, in 2007, have GHG inventories and a national registry been established and the responsibilities for implementation of the Protocol and JI among the government departments have been distributed only to a certain extent. Some constraints hindering JI projects, such as vague legislation, an unfavourable economic climate, lack of commitment to JI projects, corruption, xenophobia, state and agency ‘capture’ still remain.   相似文献   
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Abstract An examination of big‐city newspaper coverage of violent crimes in small towns during a recent five‐year period reveals a remarkable degree of uniformity in the language reporters use to characterize life in these places. The cliches signal an underlying set of stereotypes of small‐town life: They are safe, close‐knit communities where bad things are “not supposed to happen.” Yet the point of the stories is that bad things do happen. Drawing upon culturological and sociological approaches to the study of news production, this paper argues that the small towns described in the news are symbolic landscapes that reflect a pastoral orientation among journalists and in the culture at large.  相似文献   
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Prevention continues to gain importance among the strategies open for governmental development of social policy. This paper offers two exploratory conceptual discussions related to prevention in social policy. The first is a representation of the policy making environment with special reference to the informational requirements for the development of policy. The second is a discussion of social pathologies, broadly defined as patterns of behavior with important negative repercussions on individuals whom we refer to as victims, and of possible strategies toward the development of (at least partial) preventive measures. The two discussions are interrelated as the shape of the second is dictated by the desiderata outlined in the first. The paper is divided into five parts:
  1. Introduction: the conundrum of prevention.
  2. The Development of a paradigm of the policy context.
  3. Dependent variables: social pathologies.
  4. Independent variables: a focus on structural determinants.
  5. Conclusion: information requirements for preventive action.
  相似文献   
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