A clinical perspective on ethical issues in genetic testing

Genetic testing is traditionally preceded by counselling to discuss its advantages and disadvantages with individuals so they can make informed decisions. The new technique of whole genome or exome sequencing, which is currently only used in research settings, can identify many gene mutations, including substantial numbers of mutations with unknown pathological effect; it may, therefore, threaten this balanced approach if it is used in a clinical setting. We discuss the ethical challenges of several approaches to pre- and postnatal DNA testing, individual privacy versus the interests of families and of scientists, and the clinician's duty to re-contact if new information or options become available.     

Towards an evaluation of a business school graduate programme

An evaluation research methodology, which has been validated in a previous study, and which was developed to be both scientifically defensible and feasible from a practical point of view, is described. This involves collecting course participants' judgements about the effects of the course, and taking steps to ensure that the process by which the participants arrive at these judgements is sound. The application of this methodology to a course in business administration revealed the following effects or consequences: (1) Access to and progress in successful careers; (2) Flexibility and mobility in careers; (3) Ability to take overall view of problems; (4) Personal confidence; (5) Awareness of own aspirations and career fit; (6) Frustration from unused skills and unfulfilled expectations; (7) High salaries; (8) General reasoning and problem solving ability; (9) Economic/commercial understanding; (10) Understanding of organisation and human behaviour; (11) Useful work, career and personal contacts; (12) Social skills.