Interleukin-18 and testosterone levels in men with metabolic syndrome

Objective: Interleukin 18 (IL-18) is an adipokine associated with obesity. Data about the relationship of IL-18 to the metabolic syndrome (MS) are still scarce. Low testosterone (T) levels are common in men with MS, but we did not find data about the levels of IL-18 in men with low T. The aim of this study was to determine the levels of IL-18 in men with MS with or without low T.

Patients and methods: A total of 251 men were included in the study. Of them 218 had MS (IDF 2005) and they were divided according to their morning total testosterone (TT) level (cutoff 10.4?nmol/l) into two groups: MS-low T (N?=?84) and MS-normal T (N?=?134). The control group consisted of 33 men without MS and low T. IL-18 was determined in serum using enzyme-linked immunosorbent assay. A small group of eight men with MS and low T levels received testosterone therapy for three months and physical and laboratory parameters were monitored at the end of that period.

Results: MS men were at mean age (±SD)?=?53.77?±?9.59 years; body mass index (BMI)?=?34.0?±?6.3?kg/m²; and TT?=?12.59?±?5.66?nmol/l. The control group was at age?=?52.12?±?5.2 years (NS); BMI?=?25.6?±?2.4?kg/m² (p?p?p?p?p?p?Conclusions: In this study, higher IL-18 levels were found in the presence of MS compared to healthy men, but they did not differ between men having MS with or without LOH.     

Managing Change in Nonprofit Organizations: Insights from the UK Charity Retail Sector

Moves toward increased professionalism are now an almost taken-for-granted aspect of change across the nonprofit sector both in the United States and in the United Kingdom. This paper uses the case of UK charity retail to explore the impacts of this move to professionalism, on managers at the local level. In doing so it seeks to develop appropriate techniques for managing change both in charity retail and more broadly, in nonprofit organizations per se. The professionalization of charities' trading activities has resulted in a series of changes at the local level; these include the introduction of new forms of staff, changes to policies regarding the sourcing, pricing, and presentation of stock, and an increased emphasis on sales targets, league tables, and incentive schemes designed to motivate managers to increase sales. These policies set at head office level have had significant impact on the day-to-day working experiences of branch managers. This paper explores managers' reactions to these changes and examines the extent to which such policies could be said to be successful. To conclude, recommendations are made as to the most appropriate approaches to professionalizing charity retail operations. These conclusions are broadened to offer insights into appropriate techniques for managing change in nonprofit organizations.     

Sequential and Simultaneous Decision Making for Optimizing Health Care Resource Flexibilities

Health care administrators commonly employ two types of resource flexibilities (demand upgrades and staffing flexibility) to efficiently coordinate two critical internal resources, nursing staff and beds, and an external resource (contract nurses) to satisfy stochastic patient demand. Under demand upgrades, when beds are unavailable for patients in a less acute unit, patients are upgraded to a more acute unit if space is available in that unit. Under staffing flexibility, nurses cross‐trained to work in more than one unit are used in addition to dedicated and contract nurses. Resource decisions (beds and staffing) can be made at a single point in time (simultaneous decision making) or at different points in time (sequential decision making). In this article, we address the following questions: for each flexibility configuration, under sequential and simultaneous decision making, what is the optimal resource level required to meet stochastic demand at minimum cost? Is one type of flexibility (e.g., demand upgrades) better than the other type of flexibility (e.g., staffing flexibility)? We use two‐stage stochastic programming to find optimal resource levels for two nonhomogeneous hospital units that face stochastic demand following a continuous, general distribution. We conduct a full‐factorial numerical experiment and find that the benefit of using staffing flexibility on average is greater than the benefit of using demand upgrades. However, the two types of flexibilities have a positive interaction effect and they complement each other. The type of flexibility and decision timing has an independent effect on system performance (capacity and staffing costs). The benefits of cross‐training can be largely realized even if beds and staffing levels have been determined prior to the establishment of a cross‐training initiative.     

The unique relationship between childhood sexual abuse,self-injury and suicide ideation: The mediating role of emotion dysregulation

Child sexual abuse (CSA) has serious short-term and long-term effects, including non-suicidal self-injury (NSSI) and suicidal ideation (SI). One possible thread linking CSA to NSSI and suicide risk is emotion dysregulation. The current study assessed whether facets of emotion dysregulation mediated relations of NSSI behaviours and functions, and SI. Participants (N = 121; Mean age = 18.69, age-range 18–22; 78 per cent female), college students with a history of childhood trauma, completed an online survey. Results indicated that facets of emotion dysregulation (i.e. clarity, non-acceptance) mediated the relationship between CSA and SI. CSA was associated with automatic negative reinforcement, social negative and social positive reinforcement NSSI functions, but was not associated with NSSI behaviours. Emotion dysregulation facets did not mediate the relationship between CSA and NSSI functions. Findings highlight the need to help CSA survivors have clarity and acceptance of emotional experiences to reduce SI risk. This research did not receive any specific grant from funding agencies in the public, commercial or not-for-profit sectors.     

Volunteers in charity retailing: Recruitment and training

Volunteer activity has received considerable research attention in recent years. There is, however, little academic research to date into volunteer issues in charity retailing. This article examines volunteers in charity shops and reports, in particular, on how volunteers are recruited and trained in the charity retailing. This article examines volunteers in charity shops and reports, in particular, on how volunteers are recruited and trained in the charity sector. The authors conclude that in an increasingly competitive market, charity retailers need to reexamine their recruitment and training policies in order to attract and retain a diverse core of volunteers.     

Projecting Long-Term Care Expenditure in Four European Union Member States: The Influence of Demographic Scenarios

This study examines the sensitivity of future long-term care demand and expenditure estimates to official demographic projections in four selected European countries: Germany, Spain, Italy and the United Kingdom. It uses standardised methodology in the form of a macro-simulation exercise and finds evidence for significant differences in assumptions about demographic change and its effect on the demand for long-term care, and on relative and absolute long-term care expenditure. It concludes that mortality-rate assumptions can have a considerable influence on welfare policy planning. Relative dispersion between country-specific and Eurostat official estimates was found to be higher for the United Kingdom and Germany than for Italy and Spain, suggesting that demographic projections had a greater influence in those countries.

The charity shop volunteer in Scotland: greatest asset or biggest headache?

Employment patterns in various sectors of retailing have received much research attention in recent years, and investigation into charity volunteering is prolific. There is, however, little academic research to date into employment issues in charity retailing or reference to the volunteers who work in charity shops. This has been a neglected topic, left in the hands of those with particular charity interests rather than an academic topic in its own right. This paper looks at the profile of the charity shop volunteer and raises the issues of future changes in technology and competition which might have an impact on current volunteers.     

Adelina Anthony Interview with Aimee Carrillo Rowe

ABSTRACT

This interview explores how performing artist, activist, writer, director, performer Adelina Anthony stages queer women of color affects as a complex terrain to mobilize a decolonial imaginary. Anthony's characters are complex, contradictory, surly, and resilient with whom audience members connect and feel deeply. Especially for queer women of color, who rarely get to see their own experiences on film or on stage, Anthony's work provides a critical forum for discussing, imagining, naming, and envisioning the connections between our personal struggles and broader forces of imperialism, heterosexual capitalism, and settler colonialism. Through the “medicina” of gritty truth-telling and side-splitting laughter, Anthony discusses her own positionality as a coyote curandera. Through the exploratory genre of the interview, Anthony helps readers palpably engage a queer woman of color “theory in the flesh” to imagine their own creative potentialities through a compassionate lens of humility and humor.     

MANAGING TWO ROLES

The main reasons for students combining term-time employment with university life are seen as financial, although additional benefits and costs are associated with ‘earning and learning’. Most studies focus on the negative impact of combining these roles, suggesting that students’ term-time employment leads to poorer adjustment to university life in terms of academic performance, social inclusion and reduced psychological well-being. Methodological problems with previous research have made it difficult to draw firm and generalizable conclusions regarding the interrelationship between university life and term-time employment roles. The current study adopts a pluralistic approach to study the links between psychological well-being, satisfaction with academic performance and social integration and students’ term-time and vacation employment. The first phase, reported here, consisted of qualitative research. Nine focus groups were conducted with undergraduate students at Stirling University, Scotland. These data were examined using a content analysis approach. Both positive and negative aspects of combining work and studying were discussed within the focus groups. This provides a balanced picture of combining the two roles. Results are discussed in relation to the models of complementarity, spillover and separation.