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A sample size justification should be given for all clinical investigations. However, sometimes the objective of a trial is to estimate an effect with a view to planning a later definitive study. This paper describes the calculations for designing studies where one wishes to adopt an estimation approach through using confidence intervals around the overall response. Calculations are given for data anticipated to take a Normal form. Copyright © 2004 John Wiley & Sons, Ltd.  相似文献   
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It is noted that existing sociological research on classrooms has focused too narrowly on compulsory schooling with the result that we have no data showing the rituals and routines of Adult Classrooms or the ways that teachers cope and resolve them. The paper presents fieldnote and interview data from a small ethnographic study of the two Adult Evening classes. The data suggest that in contrast to the teacher of school aged pupils, who seeks control and discipline, ‘pleasing students’ is the major orientation to classroom life of the evening class teacher. Do not say, the people must be educated when after all you only mean amused, refreshed, soothed put into good spirits and good humour or kept from vicious excesses. (Newman, 1873).  相似文献   
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This article reports on the findings of research carried out on conflicts concerning major transport infrastructure projects in the Southern Alps. These conflicts were analyzed as delineating the gradual emergence of an environmental expertise network. Rather than fighting the administration and/or the transport operator in the field of transport, some opponents try to relocate the expertise into the field of the environment so as to catch the experts in the different administrations off guard. This resulting Alpine environmental expertise is based on the constitution of trans‐Alpine associative networks and the emergence of a constantly more supportive and structuring notion: sustainable development. In this article, we analyze the manner in which this notion is diffused and how it gradually builds up its definition in the course of action. The Alpine Agreement plays a major role in this operationalization: it constitutes a multilateral semantic point of reference for a variable Alpine policy and has influenced both major trans‐Alpine associative networks and official French land transport policy.  相似文献   
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When the public relations firm D-A-Y was dissolved into Ogilvy & Mather Public Relations November 1, 1988, the longest lived public relations agency disappeared into the sands of time that enveloped the first four agencies started in the first decade of the waning century. The D in D-A-Y stood for Pendleton Dudley, a venerable pioneer in this vocation, who had opened his agency in Wall Street in 1909 at the urging of his good friend, Ivy Lee. Dudley, a rugged, independent product of frontier America, headed his firm for fifty-seven years—a longevity record surpassed only by that of Edward L. Bernays, who started his firm in 1919 in the Post World War I public relations boom.Pendleton Dudley—known to his close friends as Pen and to his associates in his firm as PD, was born September 8, 1876, in a small frontier town of Troy, Missouri, when America was an agricultural nation. He came to pioneer as a counselor to the corporate giants, AT&T among them, in a complex, interdependent corporate industrial America. Pen Dudley did much to infuse this field with respectability in a time when it was viewed with suspicion or disdain in its early years. He was a strong advocate of research as the only sound basis for planning and executing programs to influence public behavior. He was also active in the Public Relations Society of America after it was formed in 1948 and was in the forefront of those creating the now extinct Foundation for Public Relations Research and Education. In 1965, he received the Distinguished Service Award from the New York PRSA Chapter. He died at the age of 90 in 1966.The author is Dean Emeritus of Journalism at the University of Georgia, and co-author Effective Public Relations, 6th Ed.  相似文献   
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Using data from a representative sample of adults age eighteen to fifty‐five who reside in Toronto, Canada, and are employed in the paid labor force, this study asks: Are the health benefits of education, income, job autonomy, and nonroutinized work different for women and men? If so, do mastery and self‐esteem contribute to those differences? Results show that women and men derive different personal benefits from socioeconomic status and job qualities: (1) education, job autonomy, and nonroutinized work are associated more positively with the sense of mastery among women, (2) job autonomy is associated more positively with self‐esteem among women, (3) education, job autonomy, and nonroutinized work are associated more negatively with depressive symptoms among women, and (4) job autonomy and nonroutinized work are associated more positively with global health among women. Moreover, the patterns in (1) and (2) explain the gender‐contingent effects in (3) and (4). In addition, unexpected suppression effects reveal that, among men, education is associated negatively with mastery and self‐esteem—but only after adjustment for job conditions. I interpret the findings in the context of the disadvantaged status thesis and speculate about status‐related social comparison processes.  相似文献   
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This article seeks to define gender issues and explores the significance of these issues for challenging behaviour in the field of learning disability. It is argued that lack of awareness about these issues contributes to the development of challenging behaviour and to difficulties in identifying the needs expressed through these behaviours, whatever their origin. Specific areas examined include models of residential provision for adults, prioritisation of service activities, attribution processes (needs identification), and the sexuality of people with learning disabilities. In each area issues are raised and the implications for service practice defined.  相似文献   
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