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In the economic and social aftermath of the 2008 crisis there has been an important and growing new wave of highly qualified Portuguese emigration comprising scientists. No or very few public policies have been designed to reverse this phenomenon, risking the consequences of brain drain. International literature argues that professional reasons are central to scientists’ decision to migrate, even after the 2008 crisis. Spending some time in a foreign country to study, research, or teach, is perceived as a common step in an individual academic trajectory and an advantage for a successful professional career in academia. It is also encouraged by European Union policies. Twelve individual portraits of Portuguese scientists living in central Europe reveal how important other factors are to the migration decision‐making process. These factors include the economic crisis, student mobility programmes, and the current Portuguese scientific system revision.  相似文献   
2.
The design of double acceptance sampling (AS) plans for attributes based on the operating characteristic curve paradigm is usually addressed by enumeration algorithms. These AS plans may be non optimal regarding the sample size to inspect as they were obtained without the requirement that the constraints at the OC curve controlled points are not violated for minimum Average Sample Number (ASN) scenarios. An approach based on mathematical programming is proposed to systematically design double AS plans for attributes, where the characteristics controlled are modelled by binomial or Poisson distributions. Specifically, Mixed Integer Nonlinear Programming (MINLP) formulations are developed and combined with an enumeration algorithm that allows finding ASN minimax optimal plans. A theoretical result is developed with the purpose of assuring the global optimum design is reached by iteration where a convenient solver is used to find local optima. To validate the algorithm, we compare our results with those of tables commonly used for practical purposes, consider different rates of risk, and setups commonly used in Lot Quality Assurance Plans (LQAS) for health monitoring programmes. Finally, we compare AS plans determined for processes described by binomial and Poisson distributions.  相似文献   
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This article presents an optimization-based approach for the design of acceptance sampling plans by variables for controlling nonconforming proportions when the standard deviation is unknown. The variables are described by rigorous noncentral Student’s t-distributions. Single and double acceptance sampling (AS) plans are addressed. The optimal design results from minimizing the average sampling number (ASN), subject to conditions holding at producer’s and consumer’s required quality levels. The problem is then solved employing a nonlinear programming solver. The results obtained are in close agreement with previous sampling plans found in the literature, outperforming them regarding the feasibility.  相似文献   
4.
Statistics and Computing - Optimal exact designs are problematic to find and study because there is no unified theory for determining them and studying their properties. Each has its own challenges...  相似文献   
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We find optimal designs for linear models using a novel algorithm that iteratively combines a semidefinite programming (SDP) approach with adaptive grid techniques. The proposed algorithm is also adapted to find locally optimal designs for nonlinear models. The search space is first discretized, and SDP is applied to find the optimal design based on the initial grid. The points in the next grid set are points that maximize the dispersion function of the SDP-generated optimal design using nonlinear programming. The procedure is repeated until a user-specified stopping rule is reached. The proposed algorithm is broadly applicable, and we demonstrate its flexibility using (i) models with one or more variables and (ii) differentiable design criteria, such as A-, D-optimality, and non-differentiable criterion like E-optimality, including the mathematically more challenging case when the minimum eigenvalue of the information matrix of the optimal design has geometric multiplicity larger than 1. Our algorithm is computationally efficient because it is based on mathematical programming tools and so optimality is assured at each stage; it also exploits the convexity of the problems whenever possible. Using several linear and nonlinear models with one or more factors, we show the proposed algorithm can efficiently find optimal designs.  相似文献   
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Minimax optimal experimental designs are notoriously difficult to study largely because the optimality criterion is not differentiable and there is no effective algorithm for generating them. We apply semi-infinite programming (SIP) to solve minimax design problems for nonlinear models in a systematic way using a discretization based strategy and solvers from the General Algebraic Modeling System (GAMS). Using popular models from the biological sciences, we show our approach produces minimax optimal designs that coincide with the few theoretical and numerical optimal designs in the literature. We also show our method can be readily modified to find standardized maximin optimal designs and minimax optimal designs for more complicated problems, such as when the ranges of plausible values for the model parameters are dependent and we want to find a design to minimize the maximal inefficiency of estimates for the model parameters.  相似文献   
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