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In this case study, we describe the symptoms, neurological examination, test results, and brain pathology of a man with Parkinson's disease (PD). PD commonly presents with tremor or changes in one's ability to walk or move. Other major difficulties caused by this disease include rigidity of the body, slowness of movement, and postural imbalance. The disease symptoms principally result from the degeneration of a specific population of neuronal cells in the brain stem, in a region called the pars compacta of the substantia nigra. Pathology shows the loss of these cells and the appearance of characteristic neuronal cytoplasmic inclusions called Lewy bodies, which are composed principally of aggregated alpha-synuclein protein. 相似文献
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Glaydston Mattos Ribeiro Miguel Fragoso Constantino Luiz Antonio Nogueira Lorena 《Journal of Combinatorial Optimization》2010,20(4):385-398
Earth observation satellites, such as the SPOT 5, take photographs of the earth according to consumers’ demands. Obtaining
a good schedule for the photographs is a combinatorial optimization problem known in the literature as the daily photograph
scheduling problem (DPSP). The DPSP consists of selecting a subset of photographs, from a set of candidates, to different
cameras, maximizing a profit function and satisfying a large number of constraints. Commercial solvers, with standard integer
programming formulations, are not able to solve some DPSP real instances available in the literature. In this paper we present
a strengthened formulation for the DPSP, based on valid inequalities arising in node packing and 3-regular independence system
polyhedra. This formulation was able, with a commercial solver, to solve to optimality all those instances in a short computation
time. 相似文献
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Player transgressions in sport relate to on- or off-field incidents that are out of the ordinary and may bring negative repercussions for stakeholders as a result of their association with the team, athlete or sport. Based on a series of depth interviews conducted with executives representing major Australian team-based sporting organizations, this paper outlines the effects that these incidents can have on relationships with sponsors from a sport organization perspective. The findings serve to develop a conceptual model that illustrates that the impact of transgressions is determined by a number of factors, which are discussed. The paper further presents a number of implications for the sport organization's public relations strategy, given that the role of public relations has evolved from primarily a communications focus to a more strategic management of relationships with various publics and stakeholders. 相似文献
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ResumenLa escala «directiveness» de Ray (1976) es uno de los instrumentos diseñados para la medición del autoritarismo. En este trabajo se estudia la relación de esta medida con el dogmatismo, orientación política, edad y sexo, variables de interés en el campo de las actitudes socio-políticas, los resultados obtenidos nos permiten concluir que la escala «directiveness» no es ütil para el fin pretendido. También se subraya la necesidad de proceder a un debate teórico más riguroso en torno al autoritarismo político. 相似文献
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JL Sligo HM McAnally JE Tansley JM Baxter AE Bolton KM Skillander 《Kōtuitui : New Zealand Journal of Social Sciences Online》2017,12(1):41-55
The living arrangements of young people in New Zealand are diverse and often complex. In this article we report the range of care and living arrangements of 209 15-year-old New Zealanders, 47 of whom identified as Māori. These young people were participants in the second generation of a cohort study. Data were collected from their parents via a life history calendar and analysed for variety and consistency of care arrangements, household membership and transitions. Few participants had a consistent pattern of parental care arrangements and most had experienced multiple changes in household composition and frequent changes of address. We conclude that the whānau/family lives of many young New Zealanders are complex and dynamic. These observations contrast with the conventional notions of family life that form the basis for New Zealand’s family policies. We argue that social policies and services impacting on young people need to reflect the lived reality of young people if they are to meet young people’s needs. 相似文献
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Melissa Gross Don Latham Karen Randolph Christopher Constantino Elliot Chance Preshia 《Child & Family Social Work》2023,28(1):14-24
This study explores the impact of information and communications technology (ICT) use on rural child welfare practice using a technology-in-practice framework to derive the social structures that are instantiated by rural child welfare workers (CWWs) and to examine their agency as actors. ICT use was tracked, and interviews were conducted with rural CWWs who work with children and families to gain an understanding of and describe their day-to-day ICT use at the practice level. Findings demonstrate that CWWs enact social structures along four frames: bureaucratic structure, family centricity, ICT context and information–documentation culture. In terms of agency, CWWs not only are constrained by but also exert some influence on the social structures they enact through facilities (material resources), norms and interpretive schemes. These findings have implications for how ICT can be used to facilitate the CWW–client relationship and the need in rural areas for increased infrastructure to support CWWs. 相似文献
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