Multiple event times in the presence of informative censoring: modeling and analysis by copulas

Motivated by a breast cancer research program, this paper is concerned with the joint survivor function of multiple event times when their observations are subject to informative censoring caused by a terminating event. We formulate the correlation of the multiple event times together with the time to the terminating event by an Archimedean copula to account for the informative censoring. Adapting the widely used two-stage procedure under a copula model, we propose an easy-to-implement pseudo-likelihood based procedure for estimating the model parameters. The approach yields a new estimator for the marginal distribution of a single event time with semicompeting-risks data. We conduct both asymptotics and simulation studies to examine the proposed approach in consistency, efficiency, and robustness. Data from the breast cancer program are employed to illustrate this research.

     

Book reviews

The Political Sociology of Florian Znaniecki and Contemporary Politics (in Polish), Olgierd Sochacki (Ed.) Wydawnictwo Gdanskie, The Scientific Society of Gdansk, 1996

Why Read. Internal Space and the Social Function of Literature: An Investigation with. Psychoanalysts and Psychology Students, Graziella Pagliano (Ed.) Bonanno Editore, 1994

Voix Littéraires de Femmes

Cuadernos sobre Vico, Nos 5–6, José M. Sevilla et al. 1995–96

Studi in memoria di Ernesto Grassi Proceedings of the International Conference in Memory of Ernesto Grassi (Ischia, 4–6 October 1993), Emilio Hidalgo‐Serna and Massimo Marassi (Eds), Napoli, La Città del Sole, 1996

Naples Istituto Italiano per gli Studi Fiosofici, La Gittà del Sole, Napoli, 1996

Family, Women and Employment in Central‐Eastern Europe, Barbara Lobodzinska (Ed.) Greenwood Press, 1995     

Validating Work Discrimination and Coping Strategy Models for Sexual Minorities

The purpose of this study was to validate and expand on Y. B. Chung's (2001) models of work discrimination and coping strategies among lesbian, gay, and bisexual persons. In semistructured individual interviews, 17 lesbians and gay men reported 35 discrimination incidents and their related coping strategies. Responses were coded based on Chung's models. Results supported the validity of the Work Discrimination model and two coping strategy models (Vocational Choice and Identity Management). The Discrimination Management coping strategy model was expanded. Implications for practice and research are discussed.     

Comparison of hazard rates for dependent random variables

In this paper, we define and study a new notion for the comparison of the hazard rates of two random variables taking into account their mutual dependence. Properties, applications and the comparison for a data set are given.     

Confidence intervals based on the deviance statistic for the hyperparameters in state space models

The main objective of this work is to evaluate the performance of confidence intervals, built using the deviance statistic, for the hyperparameters of state space models. The first procedure is a marginal approximation to confidence regions, based on the likelihood test, and the second one is based on the signed root deviance profile. Those methods are computationally efficient and are not affected by problems such as intervals with limits outside the parameter space, which can be the case when the focus is on the variances of the errors. The procedures are compared to the usual approaches existing in the literature, which includes the method based on the asymptotic distribution of the maximum likelihood estimator, as well as bootstrap confidence intervals. The comparison is performed via a Monte Carlo study, in order to establish empirically the advantages and disadvantages of each method. The results show that the methods based on the deviance statistic possess a better coverage rate than the asymptotic and bootstrap procedures.     

The Regulation of Infant Negative Emotions: The Role of Maternal Sensitivity and Infant‐Directed Speech Prosody

This study explored the role of maternal sensitivity and infant‐directed speech (IDS) prosody in infants’ expression and regulation of negative emotion. Seventy mothers and their 3‐month‐old infants were observed during the Still‐Face Paradigm (SFP). Maternal sensitivity and IDS prosody were assessed at baseline and infant negative affect in the baseline, still‐face, and reunion episodes. Results showed that prototypical IDS prosody characterized by wider fundamental frequency (F0) variability was related to decreases in infant's negative affect, but only if accompanied by maternal sensitivity. Infants of sensitive mothers who spoke with more prototypical IDS prosody showed better abilities to regulate negative affect during the SFP. When prototypical IDS prosody was accompanied by low maternal sensitivity, infants showed lower regulation of negative emotions. In conclusion, infant negative affect regulation in a dyadic setting is facilitated by an optimal combination of both more prototypical maternal IDS prosody and maternal sensitive responsiveness. Implications for the study of mother–infant interaction are discussed.     

The Pointing–Vocal Coupling Progression in the First Half of the Second Year of Life

This study investigated the development of the pointing–vocal coupling system. We were interested in the infants’ behavior to attune prosody with pointing intentions. Twenty‐five children were involved at 12, 15, and 18 months of age in an experimental procedure devised to elicit imperative and declarative pointing. Pointing, vocality associated with pointing, and the prosody of that vocality were analyzed. A significant increase in the coupling of pointing and vocality was observed from 12 to 15 months, and in the ability to differentiate prosody with respect to the intention of the gesture from 15 to 18 months. Also, the infants who pointed declaratively at 12 months were likely to couple declarative pointing with vocality at 15 months, and the infants who coupled at 15 months were likely to differentiate prosody by the pointing intention at 18 months. Results suggest that the match between prosody and pointing intentions emerges gradually during the first half of the second year of life. They also show a relationship between earlier and later pointing–vocal coupling, and a role for declarative communication in promoting that progression. Overall, our study supports the view of intentional communication as a time‐based and context‐based developmental process.