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A paradox currently exists regarding legal sports gambling in North America: various forms are flourishing in Nevada, Oregon, and several Canadian provinces, while at the same time the United States Congress is conducting hearings on two bills that would prohibit any new state-sponsored sports gambling initiatives. This study examines the issue of why some jurisdictions are enthusiastic about legal sports gambling while others strongly resist the concept. In reviewing these divergent viewpoints, a case study of the newfledged Canadian Sport Select gambling format is presented. This example is used to highly the perils and payoffs of a typical state-sponsored sports gambling scheme, with a view toward broadening our understanding of how they work and how they might be fairer to the public.  相似文献   
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Consider a randomized trial in which time to the occurrence of a particular disease, say pneumocystis pneumonia in an AIDS trial or breast cancer in a mammographic screening trial, is the failure time of primary interest. Suppose that time to disease is subject to informative censoring by the minimum of time to death, loss to and end of follow-up. In such a trial, the censoring time is observed for all study subjects, including failures. In the presence of informative censoring, it is not possible to consistently estimate the effect of treatment on time to disease without imposing additional non-identifiable assumptions. The goals of this paper are to specify two non-identifiable assumptions that allow one to test for and estimate an effect of treatment on time to disease in the presence of informative censoring. In a companion paper (Robins, 1995), we provide consistent and reasonably efficient semiparametric estimators for the treatment effect under these assumptions. In this paper we largely restrict attention to testing. We propose tests that, like standard weighted-log-rank tests, are asymptotically distribution-free -level tests under the null hypothesis of no causal effect of treatment on time to disease whenever the censoring and failure distributions are conditionally independent given treatment arm. However, our tests remain asymptotically distribution-free -level tests in the presence of informative censoring provided either of our assumptions are true. In contrast, a weighted log-rank test will be an -level test in the presence of informative censoring only if (1) one of our two non-identifiable assumptions hold, and (2) the distribution of time to censoring is the same in the two treatment arms. We also extend our methods to studies of the effect of a treatment on the evolution over time of the mean of a repeated measures outcome, such as CD-4 count.  相似文献   
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从"权利"到"仪式":南非的艾滋病行动主义   总被引:1,自引:0,他引:1  
在本文中,我考察了南非HIV/AIDS行动主义的道德政治如何有助于公民身份(citizen-ship)新形式的出现,这种新形式既与基于权利(rights-based)的斗争相关,又与个体HIV/AIDS患者对病痛和污名化(stigmatization)极端体验的共享意义相关。我指出,可以确定的是,正是晚期艾滋病患者"接近死亡"的绝境体验、以及与这种疾病晚期阶段相连的巨大污名和"社会死亡",为HIV/AIDS的幸存者对"新生命"和社会行动主义的委身提供了平台。行动主义者的干预和对这些创伤经验的重述也推动了HIV/AIDS对行动主义的委身和社会底层的动员。此外,污名和社会死亡的巨大否定性也驱使行动主义者重建对HIV检测呈阳性人群新的、正面的身份认同,并促使他们思考,作为一名公民-行动主义者和一项社会运动的成员意味着什么。  相似文献   
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This paper reviews the main bodies of contemporary urban sustainability theory. From this analysis, two underpinning paradigms of urban sustainability are identified: (1) The ‘Human Exemptionalism Paradigm’ (HEP), which emphasizes the ability of humans to overcome environmental problems—see Urban Sociology, Urban Ecology, Urban Geography, Urban Psychology and Political Economy; and (2) The ‘New Ecological Paradigm’ (NEP), which emphasizes the criticality of ecological limits to human progress—see Urban Metabolism, Energy/Emergy Analysis and Ecological Footprinting. Each of these approaches is critically reviewed, highlighting their main assumptions, theoretical and practical foci. It is argued in the paper that if the related issues of urban sustainability and development are to be progressed, there needs to be: (1) a greater maturation of the NEP approaches, which are ‘relative newcomers’ to the area of urban theory; and (2) greater integration and dialogue between the HEP and NEP approaches to urban sustainability than has hitherto been the case.
Murray G. PattersonEmail:
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