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This study explores the association between employment opportunities, psychiatric disability and quality of life of male and female patients with schizophrenia. The data were collected from 100 male and 100 female patients and their primary caregivers through personal interviews. The Disability Assessment Schedule and the Quality of Life Interview were used to collect the data. The results of the present study indicate that a large number of both the men and women were unemployed, although they suffered from only mild psychotic symptoms and had no or only minimum psychiatric disability. However, in almost all areas and levels of psychiatric disability, a significantly higher number of men than women were employed. However, the subjective Quality of Life of the employed men was significantly lower than that of the unemployed. Keeping in mind these two results, the present study argues that there is minimal community recognition in Malaysia for the employment potential of people with schizophrenia. The study also argues that policy makers must legislate to create more appropriate workplaces for the mentally ill. People with schizophrenia are entitled to just and fair treatment, and workplaces should be made attractive to them.  相似文献   
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This study examines the perceived conditions leading to Colorado adopting revised Standards for treating domestic violence offenders from the perspective of Kingdon's multiple streams theory. A within‐case analysis of ten semi‐structured interviews explores the Domestic Violence Offender Management Board in Colorado's process for revising Colorado's 2001 Treatment Standards. Findings suggest a benign political stream, supported by technically feasible and value‐accepted policy ideas, feedback and indicators of the problem, promoted a favourable setting for change. At least two policy entrepreneurs championed the decision‐making process. Agenda setting and policy formulation depended on three elements: feedback from existing programmes, indicators of continued difficulty in effectively treating offenders, and the existence of a suitable policy alternative. This study contributes a rare application of multiple streams theory to a criminal justice context in a sub‐national government. Future research should explore whether the presence of a benign political stream influences the development and revision of domestic violence policy in other policy environments.  相似文献   
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A review of the literature on organizational culture change suggests that the field might benefit from studies combining both etic (researcher) and emic (employee) perspectives to examine individuals’ views regarding how and why their culture has changed. This paper seeks to deepen researchers’ knowledge of how individuals perceive organizational culture change by undertaking a two‐part study within an organization that has undergone planned cultural change initiatives. More specifically survey (i.e. etic view) data and interview (i.e. emic view) data are used to explore: (1) factors associated with (a) whether an individual will perceive that culture change has occurred, and (b) whether they categorize this change as for the better, for the worse or one that could not be categorized using these two labels; and (2) individuals’ rationales for why the culture has changed. The findings are mixed regarding the extent to which they support or refute existing research on organizational culture change.  相似文献   
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Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) age-related withdrawal is very likely to be involved in the aging process and the onset of age-related diseases, giving rise to the question of whether preventing or compensating the decline of these steroids may have endocrine and clinical benefits. The aim of the present trial was to evaluate the endocrine, neuroendocrine and clinical consequences of a long-term (1 year), low-dose (25?mg/day) replacement therapy in a group of aging men who presented the clinical characteristics of partial androgen deficiency (PADAM). Circulating DHEA, DHEAS, androstenedione, total testosterone and free testosterone, dihydrotestosterone (DHT), progesterone, 17-hydroxyprogesterone, allopregnanolone, estrone, estradiol, sex hormone binding globulin (SHBG), cortisol, follicle stimulating hormone (FSH), luteinizing hormone (LH), growth hormone (GH) and insulin-like growth factor 1 (IGF-1) levels were evaluated monthly to assess the endocrine effects of the therapy, while β-endorphin values were used as a marker of the neuroendocrine effects. A Kupperman questionnaire was performed to evaluate the subjective symptoms before and after treatment.

The results showed a great modification of the endocrine profile; with the exception of cortisol levels, which remained unchanged, DHEA, DHEAS, androstenedione, total and free testosterone, DHT, progesterone, 17-hydroxyprogesterone, estrone, estradiol, GH, IGF-1 and β-endorphin levels increased significantly with respect to baseline values, while FSH, LH and SHBG levels showed a significant decrease. The Kupperman score indicated a progressive improvement in mood, fatigue and joint pain.

In conclusion, the present study demonstrates that 25?mg/day of DHEA is able to cause significant changes in the hormonal profile and clinical symptoms and can counteract the age-related decline of endocrine and neuroendocrine functions. Restoring DHEA levels to young adult values seems to benefit the age-related decline in physiological functions but, however promising, placebo-controlled trials are required to confirm these preliminary results.  相似文献   
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Various aspects of social learning and self-control theories have been applied to partner violence among multiple samples in the United States, but these theoretical approaches have been less commonly studied cross-culturally. Consequently, childhood maltreatment and low self-control have been identified as risk factors for various outcomes in primarily American samples. This study examined the relationships between childhood maltreatment, low self-control, and dating violence among college students in South Korea and the United States. Findings indicated that experiencing childhood maltreatment and having low self-control were key predictors of perpetration and victimization for both psychological and physical relationship violence. Witnessing interparental violence during childhood was less consistently predictive of one's involvement in a violent dating relationship. Implications for theory and policy are discussed.  相似文献   
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While prior literature generally supports the connection between child maltreatment and violent offending in adolescence and early adulthood for general population samples, less is known about the relationship between child maltreatment and the frequency of violent offending among serious juvenile offenders. As a result, few studies have examined whether the effects of child maltreatment on the frequency of violent offending are mediated by other social processes, as developmental models of aggression and violence would suggest. To examine this issue, self-report data on child maltreatment, general delinquency risk factors, and violent offending were collected from 3,694 juveniles confined to 48 correctional institutions. Results from a series of negative binomial regression models indicated that the relationship between child maltreatment and the frequency of violent offending was mediated by social risk factors. The implications of these findings for theory and practice are discussed.  相似文献   
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Hodgkin's disease is a cancer of the lymphatic system. The major feature influencing the type of treatment employed, and the ultimate prognosis, is the stage or extent of disease prior to therapy. This paper is concerned with evaluating the difference in patient progress of two staging procedures. One (pathological staging) procedure is more extensive than the other (clinical staging). The evaluation is carried out by firstly developing a mathematical model of patient progress for pathologically staged patients and then using this model to predict what would have happened to clinically staged patients if they had been treated according to their pathological stage. Comparison of these predictions with actual results suggests that pathologically staged patients appear to remain in disease free survival (remission) following radio-therapy longer than clinically staged patients.  相似文献   
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