Low dose risk estimation via simultaneous statistical inferences

Summary.  The paper develops and studies simultaneous confidence bounds that are useful for making low dose inferences in quantitative risk analysis. Application is intended for risk assessment studies where human, animal or ecological data are used to set safe low dose levels of a toxic agent, but where study information is limited to high dose levels of the agent. Methods are derived for estimating simultaneous, one-sided, upper confidence limits on risk for end points measured on a continuous scale. From the simultaneous confidence bounds, lower confidence limits on the dose that is associated with a particular risk (often referred to as a bench-mark dose ) are calculated. An important feature of the simultaneous construction is that any inferences that are based on inverting the simultaneous confidence bounds apply automatically to inverse bounds on the bench-mark dose.     

Benchmark Analysis: Shopping with Proper Confidence

We discuss the issue of using benchmark doses for quantifying (excess) risk associated with exposure to environmental hazards. The paradigm of low-dose risk estimation in dose-response modeling is used as the primary application scenario. Emphasis is placed on making simultaneous inferences on benchmark doses when data are in the form of proportions, although the concepts translate easily to other forms of outcome data.     

The Three-Item Thinking about Your Partner’s Drinking Scale (TPD-3): Item Response Theory,Reliability, and Validity

Interdependence is a defining feature of close relationships, and alcohol use is one domain where one person’s motivations and behaviors can affect a partner’s well-being. Concern about partner drinking is a gauge that determines whether a partner’s alcohol use has the potential to be problematic to the relationship, and brief and efficient measurement of this construct can be used to serve clinicians, scientists, and practitioners. Across four studies (N = 1,807), we use item response theory analysis to present a 3-item brief screening tool assessing concern about partner drinking: Thinking about your Partner’s Drinking-3 (TPD-3). The TPD-3 revealed strong test–retest reliability and expected patterns of convergent, concurrent, and incremental validity with perceived partner drinking and alcohol-related consequences, behavioral responses to partner drinking, and relationship well-being. We present the TPD-3 as a useful screening tool and for measurement of concern about partner drinking when efficient assessment is desired.     

Planning for community: understanding diversity in resident experiences and expectations of social connections in a new urban fringe housing estate,Australia

Master-planned estates are a major source of new housing for growing cities. Much research finds these residential developments lack genuine social connections between residents despite marketing of ‘close-knit’ community. Selandra Rise is a new residential development on the urban fringe of Melbourne, Australia. The estate was planned with a focus on community infrastructure and resident well-being. The resident population was younger and more culturally diverse than most other master-planned community case studies. A longitudinal research design was used to explore resident understanding, experiences and needs relating to place-based community. Interviews were conducted with residents before moving to the estate and 9–18 months after moving. Some residents considered community as an amenity provided by the master-planned environment that did not require their social participation. Others aspired to make social connections with neighbours but had varying levels of success. Past experiences which contributed to aspirations for connecting with local community, and the ways that these aims were realised or hindered, are discussed. Understanding diverse resident expectations of community and insights from their lived experience are used to make recommendations for planning new neighbourhoods and designing community development programmes.     

The Role of Media Exposure on Coordination in the Humanitarian Setting

Despite high demand and resource limitations, humanitarian organizations (HOs) typically do not share resources and/or coordinate in the field. While coordination enhances operational performance and saves costs, the general perception is that it dilutes the media attention that individual organizations might receive, and negatively influences their future donation income. In this study, we empirically unveil the impact of media exposure and operational performance on the donations obtained by HOs. Then, based on the empirical results, we develop a stylized model to characterize the structure of preferred coordination policies with respect to an organization's funding source and main mandate. Our findings shed light on the incentives and dynamics that drive behaviors in humanitarian operations and provide insights for policy makers on designing and implementing mechanisms that encourage humanitarian coordination.     

Third-Person Effect,Religiosity and Support for Censorship of Satirical Religious Cartoons

The violent attack on the staff of Charlie Hebdo and an earlier plot to kill cartoonists from the Danish newspaper Jyllands-Posten raise the issue of censorship of satirical religious cartoons to avoid potential retaliatory violence from those offended by the cartoons. With third-person effect (TPE) as the theoretical underpinning, this study examined the relationship among TPE, religiosity, and support for censorship of religious satirical cartoons. Data were collected in May 2015. A national sample of participants (N=374) was acquired through Amazon’s Mechanical Turk. The results show that individuals with a higher degree of religiosity are more likely to support censorship of satirical religious cartoons, and though TPE is not positively correlated to support for censorship, respondents’ perception of the effect of the cartoons on themselves may indicate an increased propensity for supporting censorship.     

Making it real: using standardized patients to bring case studies to life

With increases in the overall number of individuals with posttraumatic stress disorder (PTSD), nurse educators must provide experiences that help nursing students learn how to better communicate and care for individuals with this disorder. This article describes how two learning strategies-case studies and standardized patients-were combined to facilitate the development of therapeutic communication and assessment skills. Two case studies on PTSD were written, and actors were trained to portray the individuals in the case studies. Fourteen baccalaureate nursing students enrolled in a senior-level psychiatric nursing clinical course participated in this pilot alternative learning activity. This article describes the learning activity and presents student evaluations of the assignment.     

Conducting Large‐Scale Surveys in Secondary Schools: The Case of the Youth On Religion (YOR) Project

There are few published articles on conducting large‐scale surveys in secondary schools, and this paper seeks to fill this gap. Drawing on the experiences of the Youth On Religion project, it discusses the politics of gaining access to these schools and the considerations leading to the adoption and administration of an online survey. It is concluded that successful research in schools has to be planned carefully in collaboration with key members of staff, and justified as an educational activity. Providing speedy feedback was helpful to ensure schools benefited from the research and to keep them engaged with the project. © 2011 The Author(s). Children & Society © 2011 National Children’s Bureau and Blackwell Publishing Limited     

Traumatic symptomatology characteristics of adult children of alcoholics

Traumatic experience symptomatology, resiliency factors, and stress among young adults who had experienced alcoholism within their family of origin were assessed in comparison to adults who as children experienced traumatic life events other than alcoholism and those who indicated neither problem (parental alcoholism or traumatic life event) during their childhood. These three groups were compared on self-report measures of stress, resiliency, depressive symptomatology, and trauma symptoms. Results indicated adult children of alcoholics (ACOA) had more self-reported stress, more difficulty initiating the use of mediating factors in response to life events, and more symptoms of personal dysfunction than the control group. Results suggest ACOAs may develop less effective stress management strategies and present more clinically at-risk patterns of responses than their counterparts.