Genes, longevity, and technology: meeting report from the 2nd conference on functional genomics of aging in Crete

Whole-genome sequences are now available, and methods have evolved for targeting, in parallel, each gene in a genome, offering for the first time the opportunity to study the entire dynamic network of genes involved in aging. At a recent conference in Hersonissos, Crete, around 200 internationally renowned experts gathered to discuss techniques and emerging results as the science of aging undergoes a shift toward systems biology.     

Virtuelles Selbstcoaching — Konzept und erste Erfahrungen

Combining management consultation with psychotherapy in the early nineties, coaching is a real innovation. Its success story grounds on a huge market demand. Nevertheless, actual market observations revealed a declining success progress over the past years caused by two factors. The first one refers to economic reasons since coaching is a high-budget-product and focuses mainly on managers and important specialists. The second factor is a psychological one: many potential clients associate coaching with psychotherapy and therefore react with resistance. To continue the progress, it is necessary to overcome both restrictions. The solution is virtual self-coaching as an innovative combination of coaching and e-learning. It is an online-tool that guides the user through a well-defined path of problem solving questions. This is for many users attractive because of the low costs in combination with the fact that working with an online-tool is associated with further education and not therapy. Our tests have demonstrated that the program is useful for a big variety of different problems and that best results can be expected if virtual self-coaching is combined with telephone coaching.     

Coaching in Introvision für weibliche Nachwuchsführungskr?fte: Erste Ergebnisse

Besides external factors certain thoughts and emotions also constitute a difficulty for women??s career advancement competence. How these thoughts form mental blockades when clumping together and how they limit women??s freedom of action and career advancement is illustrated by the research study ??mental blockades??. This study was part of the integrated research project ??Aufstiegskompetenz von Frauen??Entwicklungspotenziale und Hindernisse??. The results show that mental blockades of female executives can be reduced with the help of introvision coaching.     

Eliciting Donor Preferences

Most charity organizations depend on contributions from the general public, but little research is conducted on donor preferences. Do donors have geographical, recipient, or thematic preferences? We designed a conjoint analysis experiment in which people rated development aid projects by donating money in dictator games. We find that our sample show strong age, gender, regional, and thematic preferences. Furthermore, we find significant differences between segments. The differences in donations are consistent with differences in donors’ attitudes toward development aid and their beliefs about differences in poverty and vulnerability of the recipients. The method here used for development projects can easily be adapted to elicit preferences for other kinds of projects that rely on gifts from private donors.     

How did we get here? The career paths of higher education fundraisers

University‐based fundraisers have career paths that are unique in that most do not come to their careers through traditional training programs that are available to other professions, which may impact their expectations of and experiences in their work. Using the conceptual framework of person‐in‐environment fit, this study uses qualitative data from semistructured interviews of 44 higher education fundraisers to understand factors influencing their career trajectories. While formal educational backgrounds do not necessarily provide specific skills necessary for a fundraising career, findings show that many rely on on‐the‐job training, which was at times inadequate. Findings also counter common reports of fundraisers as “falling into the profession” when choosing to join the fundraising field and demonstrate how organizational factors can influence recruitment and retention.     

C. elegans gives the dirt on aging

The worm Caenorhabditis elegans has become a popular model organism for the study of mechanisms involved in aging. The C. elegans life span is controlled by several pathways that have been extensively characterized at the molecular level. These include pathways that regulate metabolism and development (namely, the insulin/IGF-1 pathway), nutrition, mitochondrial activity, and reproduction. Presentations at a recent C. elegans conference add to the growing body of knowledge about the genetic networks that control the complex process of aging and suggest new avenues for further investigations.     

Voluntary work in the Norwegian long-term care sector: complementing or substituting formal services?

ABSTRACT

Across Europe, governments call for increased involvement of volunteers to shoulder some of the welfare burden. Nevertheless, there is little research into what kind of work and how much volunteers currently contribute in the long-term care services and whether this has the potential to substitute formal services. Drawing on findings from a survey of employees in Norwegian nursing homes and home care districts, we examine the nature and volume of voluntary, unpaid work in the long-term care services in Norway. Our data suggest that volunteers to a very limited degree carry out work that has traditionally been considered the formal system’s domain: personal care and practical help. Nearly all the voluntary, unpaid contributions in our data takes place within cultural, social and other activities aimed at promoting mental stimulation and well-being, indicating a classic specialisation of tasks between volunteers and professionals. However, there has been an expansion of the formal care system to include activities aimed at promoting well-being in recent decades. This may indicate that there is a certain level of task sharing between voluntary and formal care. Thus, social workers need to consider voluntary service provision when assessing the needs of clients.     

Flows with unit path capacities and related packing and covering problems

Since the seminal work of Ford and Fulkerson in the 1950s, network flow theory is one of the most important and most active areas of research in combinatorial optimization. Coming from the classical maximum flow problem, we introduce and study an apparently basic but new flow problem that features a couple of interesting peculiarities. We derive several results on the complexity and approximability of the new problem. On the way we also discover two closely related basic covering and packing problems that are of independent interest. Starting from an LP formulation of the maximum s-t-flow problem in path variables, we introduce unit upper bounds on the amount of flow being sent along each path. The resulting (fractional) flow problem is NP-hard; its integral version is strongly NP-hard already on very simple classes of graphs. For the fractional problem we present an FPTAS that is based on solving the k shortest paths problem iteratively. We show that the integral problem is hard to approximate and give an interesting O(log?m)-approximation algorithm, where m is the number of arcs in the considered graph. For the multicommodity version of the problem there is an $O(\sqrt{m})Since the seminal work of Ford and Fulkerson in the 1950s, network flow theory is one of the most important and most active areas of research in combinatorial optimization. Coming from the classical maximum flow problem, we introduce and study an apparently basic but new flow problem that features a couple of interesting peculiarities. We derive several results on the complexity and approximability of the new problem. On the way we also discover two closely related basic covering and packing problems that are of independent interest. Starting from an LP formulation of the maximum s-t-flow problem in path variables, we introduce unit upper bounds on the amount of flow being sent along each path. The resulting (fractional) flow problem is NP-hard; its integral version is strongly NP-hard already on very simple classes of graphs. For the fractional problem we present an FPTAS that is based on solving the k shortest paths problem iteratively. We show that the integral problem is hard to approximate and give an interesting O(log m)-approximation algorithm, where m is the number of arcs in the considered graph. For the multicommodity version of the problem there is an O(?m)O(\sqrt{m}) -approximation algorithm. We argue that this performance guarantee is best possible, unless P=NP.     

Effectiveness of the International Child Development Programme: Results from a randomized controlled trial

This study aimed to evaluate the effectiveness of the International Child Development Programme (ICDP), a group-based parenting programme used internationally and implemented nationally in Norway. We used a cluster randomized controlled trial in which 81 groups were randomly assigned to either the intervention or waitlist control condition after the baseline data collection. A total of 590 parents completed at least one of three questionnaires (administrated before and after ICDP and 4 months after completing the intervention). Primary outcomes included parental self-efficacy, parental emotion sensitivity and positive involvement with their child. Secondary outcomes included parents' perceptions of their relationship with the child, child-rearing conflicts and the child's psychosocial health. We found significant effects favouring the intervention arm following the intervention and at follow-up on two primary outcomes (parental self-efficacy and emotion sensitivity). For the secondary outcomes, we found a significant reduction in child-rearing conflict at the 4-month follow-up, increased closeness to the child, reduced child internalizing difficulties and increased prosocial behaviour immediately following the intervention. However, ICDP seems to have limited effects on parent-reported changes in children. We conclude that ICDP as a universal preventive programme offered to parents in groups can be effective in strengthening parental self-efficacy and improving parental emotion sensitivity.