Family Involvement and Holocaust Salience among Offspring and Grandchildren of Holocaust Survivors

The present research focuses on family involvement reported by offspring and grandchildren of Holocaust survivors (OHS and GHS, respectively). Study 1 included a convenience sample of 75 participants, divided into 2 groups (36 OHS and 39 comparisons). Study 2 included a convenience sample of 92 dyads of OHS and GHS. Both samples completed the Family Involvement Questionnaire and the Holocaust Salience Scale. In line with the hypotheses, Study 1 found that, relative to comparisons, OHS presented greater familial involvement. Only OHS with strong family involvement showed higher Holocaust salience than comparisons. Study 2 showed higher familial involvement among OHS as compared to GHS, and significant parent-child correlations. The results show that family involvement is related to intergenerational transmission of the trauma, especially among OHS. Yet, among OHS and GHS, parents’ and children’s family involvement were associated. The theoretical and practical implications of these findings are discussed.     

Poverty,Government Policy and Public Opinion in Britain and Israel: A Comparative Analysis

What are the effects of public opinion on social welfare policies? To what extent is increased financial strain associated with stronger support for anti‐poverty policies? This article tests welfare state theory by comparing poverty, government policy and public opinion on poverty in the UK and Israel, based on rich and detailed comparable survey data on the conditions of the poor in both countries. The results show that, despite similar levels of income poverty and inequality, the poor have a considerably lower standard of living in Israel than the UK. There is considerably greater public support for the poor in Israel but limited government action to end poverty, whereas in the UK there is more limited public support for the poor but significant government action on poverty and exclusion. In both countries there appears to be only a limited connection between social solidarity with the poor and the political elite's rhetoric and action.     

A semiparametric Bayesian model for repeatedly repeated binary outcomes

Summary.  We discuss the analysis of data from single-nucleotide polymorphism arrays comparing tumour and normal tissues. The data consist of sequences of indicators for loss of heterozygosity (LOH) and involve three nested levels of repetition: chromosomes for a given patient, regions within chromosomes and single-nucleotide polymorphisms nested within regions. We propose to analyse these data by using a semiparametric model for multilevel repeated binary data. At the top level of the hierarchy we assume a sampling model for the observed binary LOH sequences that arises from a partial exchangeability argument. This implies a mixture of Markov chains model. The mixture is defined with respect to the Markov transition probabilities. We assume a non-parametric prior for the random-mixing measure. The resulting model takes the form of a semiparametric random-effects model with the matrix of transition probabilities being the random effects. The model includes appropriate dependence assumptions for the two remaining levels of the hierarchy, i.e. for regions within chromosomes and for chromosomes within patient. We use the model to identify regions of increased LOH in a data set coming from a study of treatment-related leukaemia in children with an initial cancer diagnostic. The model successfully identifies the desired regions and performs well compared with other available alternatives.     

Optimal sampling times in population pharmacokinetic studies

We propose a simulation-based approach to decision theoretic Bayesian optimal design. The underlying probability model is a population pharmacokinetic model which allows for correlated responses (drug concentrations) and patient-to-patient heterogeneity. We consider the problem of choosing sampling times for the anticancer agent paclitaxel, using criteria related to the total area under the curve, the time above a critical threshold and the sampling cost.     

A preliminary study of group intervention along with basic canine training among traumatized teenagers: A 3-month longitudinal study

The current study aimed to reduce the psychological distress of teenage girls who were exposed to traumatic event (physical or sexual abused), through using dogs-assisted therapy. Two sets of designs conducted: 1) longitudinal design which aims to answer the question: does dog assisted therapy will reduce psychological distress (namely depressive symptoms, post-traumatic symptoms), improve self confidence and subjective well being among these teenage girls? 2) Cross-sectional design that aims to compare the treatment group (dogs-assisted therapy) with comparison group at baseline and after the last session. The groups (intervention vs. matching) were compared on socio-demographic variables (only for time 1), subjective well-being, coping with stressful life events, PTSD symptoms, and depressive symptoms at base line (time 1) and at the end of the intervention (time 2). Findings from the longitudinal perspective have shown a rapid decline at the level of PTSD symptoms in the intervention group, along with significant reduction in the proportion of participants with elevated risk for PTSD. The main significant findings from the cross-sectional design were: lower level of subjective well-being, higher level of PTSD symptoms and depressive symptoms among the intervention group compared to the matching group at base line. However, these differences became non-significant at the end of the intervention. Various explanations for these findings are discussed.     

Tourette's syndrome

1. Tourette's syndrome is a disorder with a multitude of complex behavioral problems with major implications for social impairment and emotional pain. 2. The generic care plan anticipates the predictable management problems in adolescent patients. It offers nursing interventions, particularly structure, which is important in managing symptoms. 3. The treatment process is slow. The successful implementation requires consistent efforts from the nursing staff, treatment team, and family.