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1.
The Value of Information in Decision‐Analytic Modeling for Malaria Vector Control in East Africa
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Dohyeong Kim Zachary Brown Richard Anderson Clifford Mutero Marie Lynn Miranda Jonathan Wiener Randall Kramer 《Risk analysis》2017,37(2):231-244
Decision analysis tools and mathematical modeling are increasingly emphasized in malaria control programs worldwide to improve resource allocation and address ongoing challenges with sustainability. However, such tools require substantial scientific evidence, which is costly to acquire. The value of information (VOI) has been proposed as a metric for gauging the value of reduced model uncertainty. We apply this concept to an evidenced‐based Malaria Decision Analysis Support Tool (MDAST) designed for application in East Africa. In developing MDAST, substantial gaps in the scientific evidence base were identified regarding insecticide resistance in malaria vector control and the effectiveness of alternative mosquito control approaches, including larviciding. We identify four entomological parameters in the model (two for insecticide resistance and two for larviciding) that involve high levels of uncertainty and to which outputs in MDAST are sensitive. We estimate and compare a VOI for combinations of these parameters in evaluating three policy alternatives relative to a status quo policy. We find having perfect information on the uncertain parameters could improve program net benefits by up to 5–21%, with the highest VOI associated with jointly eliminating uncertainty about reproductive speed of malaria‐transmitting mosquitoes and initial efficacy of larviciding at reducing the emergence of new adult mosquitoes. Future research on parameter uncertainty in decision analysis of malaria control policy should investigate the VOI with respect to other aspects of malaria transmission (such as antimalarial resistance), the costs of reducing uncertainty in these parameters, and the extent to which imperfect information about these parameters can improve payoffs. 相似文献
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Jamie M. Lawler Erika L. Bocknek Ellen W. McGinnis Cecilia Martinez‐Torteya Katherine L. Rosenblum Maria Muzik 《Infancy》2019,24(2):249-274
The current study examined the role of hypothalamic‐pituitary‐adrenal reactivity (a physiological indicator of stress) in early infancy as a mediator of the relationship between maternal postpartum depression and toddler behavior problems. Participants were 137 at‐risk mothers and their children participating in a longitudinal study of intergenerational transmission of risk. Mothers’ depression was measured five times during the infants’ first 18 months. Infant cortisol was collected during a social stressor (the still‐face paradigm) when infants were 6 months old, and mothers reported on toddlers’ internalizing and externalizing symptoms at 18 months. Among this sample of high‐risk mother–infant dyads, early postpartum depression predicted atypical infant cortisol reactivity at 6 months, which mediated the effect of maternal depression on increased toddler behavior problems. Clinical implications are discussed. 相似文献
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People with criminal records in the United States continue to face limited employment opportunities due to social stigma and legal barriers. In contrast to the civilian sector, the military conducts a “whole person” evaluation to screen potential recruits and regularly hires people with felony and misdemeanor records. Moreover, evidence suggests that the military serves as a socially integrative institution and may facilitate desistance from future crimes. However, critics argue that the military exacerbates inequalities by subjecting marginalized communities to the unequal burden of service. Using the data obtained from the Army, we examine the relative risks of combat exposure and casualties between enlisted soldiers with and without criminal records who joined between 2002 and 2009. The results suggest that soldiers with felony and misdemeanor records are more likely to be assigned to combat occupations than those without criminal records. We also find that among soldiers assigned to positions with low combat exposure, ex-offenders face a higher risk of death compared to those without criminal records. Findings do not dispute the idea that the military facilitates desistance from future crimes and provides second chances to people with criminal records, but reaffirm the fact that military service costs lives and limbs. 相似文献
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Katherine Martinez 《Journal of homosexuality》2018,65(10):1299-1324
This mixed-methods study of BDSM investigates the nuances of BDSM participants’ role identities, role frequencies, and role fluidities—shifts in identities and play across time, location, scene, and play partner. Data were gathered from 202 online surveys and 25 semistructured interviews about participants’ roles given their gender and sexual identities. These data reveal that men tend to self-identify as Dominant, Master, Top, or Sadist (DMTS) and always perform dominant roles, while women tend to self-identify as Submissive, Slave, Bottom, or Masochist (SSBM) and always perform submissive roles. Although this would seem to support the theory that BDSM reinforces gendered dominant/submissive binaries, further analyses indicate that women and queer/pansexual individuals disrupt this binary through their Switch identities and roles. Switching and queer identities, thus, offer the possibility for transforming dominant/submissive and other binaries. 相似文献
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The work of hospital food service is characterized by demands that can be associated with work ability--WA. The aim of this study was to evaluate factors associated with WA among hospital food service professionals and recommend intervention measures. This is a cross sectional study carried out in 2009, conducted in a hospital of S?o Paulo, Brazil. Participants were 76 (96.2%) of the eligible. They filled out a questionnaire including socio-demographic data, life styles, working conditions and WA. Multivariate linear regression analyses were performed. Factors associated with WA were age (p = 0.051), over commitment (p = 0.011), effort-reward ratio (p = 0.002) and work injuries (p < 0.001). In spite was a young population, age was associated with WA. Association with work injuries is consistent with the theoretical model that demonstrated that health status is the basis to maintain the WA. The association of effort-reward imbalance shows that issues related with work organization are relevant for these workers. The association of overcommittment suggests that workers recognize their responsibility with the therapeutic processes of patients. Results showed a number of features of different nature that should be taken into account when implementing measures to improve the WA, to be applied at different levels: individual, task and institutional. 相似文献
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de Miranda Prottes V Oliveira NC de Oliveira Andrade AB 《Work (Reading, Mass.)》2012,41(Z1):3301-3307
This paper introduces the Ergonomic Work Analysis as a relevant instrument to identify the risks in occupational environments through the investigation of factors that influence the relationship between the worker and the productive process. It draws a parallel between the several aspects of risk identification in traditional tools of Health and Safety Management and the factors embraced by the Ergonomic Work Analysis, showing that the ergonomic methodology is able to go deeper in the scenarios of possible incident causes. This deepening enables the establishment of a relationship between the work context and the upcoming damage to the physical integrity of the worker. It acts as a complementary instrument in the traditional approach to the risk management. In order to explain the application of this methodology in a preventive way, it is presented a case study of a coal mill inspector in a siderurgic company. 相似文献
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This paper studies the internal mechanisms that allow organisations to become high value manufacturing (HVM). Using a qualitative methodology, three UK manufacturing companies formed in-depth case studies with semi-structured interviews, observations and historical data. The HVM value matrix of Martinez and co-workers is used to categorise each organisation’s value proposition. Wider benchmarking of the three organisations was carried out against a focus group with an additional seven manufacturing organisations. Thus, data from 10 manufacturing organisations are included in this research. The cases follow the ‘customer intimacy’ HVM discipline. The business processes supporting these value propositions were identified. Interestingly, each organisation’s desired value proposition differs from their current one. ‘Technological integrators’ predominantly rely on new product development (NPD) and Strategy processes, whereas ‘Socialisors’ rely predominantly on Strategy and Customer Relationship processes. Companies can use the findings to better understand their current HVM value proposition and, where necessary, plan their transition to a future desired HVM value proposition. 相似文献
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We investigate how to combine marginal assessments about the values that random variables assume separately into a model for the values that they assume jointly, when (i) these marginal assessments are modelled by means of coherent lower previsions and (ii) we have the additional assumption that the random variables are forward epistemically irrelevant to each other. We consider and provide arguments for two possible combinations, namely the forward irrelevant natural extension and the forward irrelevant product, and we study the relationships between them. Our treatment also uncovers an interesting connection between the behavioural theory of coherent lower previsions, and Shafer and Vovk's game-theoretic approach to probability theory. 相似文献
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