Improving Weight of Evidence Approaches to Chemical Evaluations

Federal and other regulatory agencies often use or claim to use a weight of evidence (WoE) approach in chemical evaluation. Their approaches to the use of WoE, however, differ significantly, rely heavily on subjective professional judgment, and merit improvement. We review uses of WoE approaches in key articles in the peer‐reviewed scientific literature, and find significant variations. We find that a hypothesis‐based WoE approach, developed by Lorenz Rhomberg et al., can provide a stronger scientific basis for chemical assessment while improving transparency and preserving the appropriate scope of professional judgment. Their approach, while still evolving, relies on the explicit specification of the hypothesized basis for using the information at hand to infer the ability of an agent to cause human health impacts or, more broadly, affect other endpoints of concern. We describe and endorse such a hypothesis‐based WoE approach to chemical evaluation.     

Institutional Activism: Seeking Customary Forest Rights Recognition from Within the Indonesian State

This article aims to explain why the adat movement activists in Indonesia could expand their campaigns for state recognition of adat community rights to activities from within the state apparatus. We argue that three combined processes have contributed to the conjuncture that made institutional activism possible: the preparation of the 2014 national election offered activists opportunities to influence the government agenda; the emergence of a conscious strategy for conducting institutional activism; and the coalitions between some key state officials and the movement’s actors. This article also analyses the problems that institutional activists faced, in particular resistance from influential actors at various government units who were not sympathetic to the adat movement’s agenda. Therefore, the impact of this activism on policy changes so far remains limited. The authors’ personal involvement in this case of institutional activism to promote customary forest provided access to the information for this article.