Determination of oxidative stress levels and some antioxidant enzyme activities in prostate cancer

In this study, the antioxidant enzyme activities such as (SOD, GSH, and CAT) and malondialdehyde (MDA) level which is the end product of lipid peroxidation, were determined from the serum samples taken from patients diagnosed with prostate cancer Van Yuzuncu Y?l University Medical Faculty of Educational Research and Training Hospital and ?stanbul Bagcilar Education Research Hospital. The SOD, GSH, and CAT activity of patient groups was found significantly lower than the healthy control group in patients with prostate cancer (p?相似文献   

Strategic Learning and the Topology of Social Networks

We consider a group of strategic agents who must each repeatedly take one of two possible actions. They learn which of the two actions is preferable from initial private signals and by observing the actions of their neighbors in a social network. We show that the question of whether or not the agents learn efficiently depends on the topology of the social network. In particular, we identify a geometric “egalitarianism” condition on the social network that guarantees learning in infinite networks, or learning with high probability in large finite networks, in any equilibrium. We also give examples of nonegalitarian networks with equilibria in which learning fails.     

Estimation of Population Variance from Multi-ranker Ranked Set Sampling Designs

In this article, we develop an estimator for a population variance based on a multi-ranker ranked set sampling design. In a multi-ranker design, the units are ranked by more than one ranker allowing ties whenever the confidence level of the rankers is low. The ranking information of all rankers is then combined in a meaningful way to create a single measure. This measure is used to construct the sampling design and a new estimator for the population variance. The article investigates the bias and relative efficiency of the proposed variance estimator. It is shown that the new estimator performs as good as or better than its competitors in the literature.     

Age and total and free prostate-specific antigen levels for predicting prostate volume in patients with benign prostatic hyperplasia

Objectives: To investigate the predictive values of free prostate-specific antigen (fPSA), total PSA (tPSA) and age on the prostate volume.

Methods: The data of 2148 patients with lower urinary tract symptoms were analyzed retrospectively. The patients who had transrectal ultrasonography guided 10 core biopsies owing to the findings obtained on digital rectal examination and presence of high PSA levels (PSA?=?2.5–10?ng/dl), and proven to have BPH histopathologically were included in the study. Age, tPSA, fPSA and the prostate volumes (PV) of the patients were noted.

Results: One thousand patients that fulfilled the inclusion criteria were included in the study. The PV of the patients were significantly correlated with age, tPSA and fPSA (p?r?=?0.307, p?r?=?0.382, p?r?=?0.296, respectively). On linear regression model, fPSA was found as a stronger predictive for PV (AUC?=?0.75, p?p?p?=?0.013).

Conclusions: Although tPSA is an important prognostic factor for predicting PV, the predictive value of fPSA is higher. PV can easily be predicted by using age, and serum tPSA and fPSA levels.     

Nonviolent Resistance: Helping Caregivers Reduce Problematic Behaviors in Children and Adolescents

In this review, the principles of nonviolent resistance (NVR) and studies examining its acceptability and efficacy are reviewed. Originating in the sociopolitical field, NVR has been adapted for numerous settings including parents of youth with externalizing and other problems, foster parents, teachers and school personnel, and caregivers of psychiatric inpatients. NVR has also been applied to reduce accommodation of highly dependent adult children and to improve novice driving habits. The principles of NVR include refraining from violence, reducing escalation, utilizing outside support, and maintaining respect for the other.     

Parental Support for Basic Psychological Needs and Happiness: The Importance of Sense of Uniqueness

Past empirical research relying on self-determination theory (SDT) has consistently shown that parental support of basic psychological needs (BPN) is associated with adolescent happiness. Yet, the specific mechanisms accounting for this link are still undetermined. The present study aimed to address this gap in the literature by testing a theoretical model proposing that adolescents’ satisfaction of BPN in life and sense of uniqueness mediate the association of parental support for BPN and happiness. The analyses relied on structural equation modeling and bootstrapping procedures and found support for the model. The theoretical implications of the model for SDT and applied considerations to improve the well-being of adolescents are discussed. Also, suggestions for future research that could further improve our understanding of the dynamic interplay between BPN, sense of uniqueness and happiness are presented.     

Run statistics in a sequence of arbitrarily dependent binary trials

Let {Z _i } _i≥1 be an arbitrary sequence of trials with two possible outcomes either success (1) or failure (0). General expressions for the exact distributions of runs, both success and failure, in Z ₁, . . . , Z _n are presented. Our method is based on the use of joint distribution of success and failure run lengths and unifies the results on distribution of runs. As a special case of our results we obtain the distributions of runs for various binary sequences. As illustrated in the paper the results enable us to derive the distribution of runs for binary trials arising in urn models.     

A modified hierarchical production planning system integrated with MRP: A case study

In this paper, a hierarchical planning system is proposed which integrates aggregate capacity planning with MRP. This system is to be implemented in a metal box manufacturing company which multi-user MRP system covering manufacturing activities as well as procurement sales order processing and accounting systems. The hierarchical planning system includes a medium-range aggregate planning model adapted to the firm's requirements and strategies. The model consists of a mathematical formulation which covers labour capacity has already installed a constraints and includes certain cost estimations in the objective function. The planning horizon of the medium range planning is taken as twelve months in order to cover sales seasonality. The aggregate production quantities resulting from the optimized medium-range planning model are disaggregated according to procedures already found in the literature. Furthermore, the theoretical infeasibilities pertaining to the disaggregation procedures are also resolved in an heuristic manner. Using the latter modified disaggregation procedure, a feasible disaggregated plan is generated for the whole planning horizon. The proposed plan is compared with the current production policy of the firm and it is observed that the proposed plan leads to backorder reduction.     

Inference in the presence of ranking error in ranked set sampling

The author proposes inference techniques for ranked set sample data in the presence of judgment ranking errors. He bases his analysis on the models of Bohn & Wolfe (1994) and Frey (2007a, b), of which parameters are estimated by minimizing a distance measure. He then uses the fitted models to calibrate confidence intervals and tests. He shows the validity of his approach through simulation and illustrates its application through the construction of distribution‐free confidence intervals for the median area of apple tree leaves covered by a spray.