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Introduction The Aging Male Symptoms' (AMS) scale was designed as a health-related quality of life (QoL) scale and standardized as a self-administered scale, first, to assess symptoms of aging (independent from those which are disease-related) between groups of males under different conditions, second, to evaluate the severity of symptoms/QoL over time, and, third, to measure changes pre- and post-androgen replacement therapy. The scale is in widespread use (17 languages currently available) and a recent review of methodological data documented good psychometric characteristics and ability as a clinical utility. This paper describes test characteristics of the AMS (positive and negative predictive values), taking two internationally established and published screening scales for androgen deficiency as the available standard.

Method A sample of 150 German males aged 40–69 years completed the AMS scale and two screening scales for androgen deficiency: the ADAM scale of Morley and colleagues and the screener of Smith and colleagues. The technique of a computer-assisted telephone interview was applied.

Result The comparison of the AMS with the two screening instruments for androgen deficiency showed sufficiently good compatibility despite conceptual differences. The AMS scale sufficiently predicted the results of the two screening instruments. A positive predictive value of 92% and a negative predictive value of 50% were found regarding the ADAM scale. The respective figures regarding Smith's screener were 65% and 49% for positive and negative predictive values, respectively.

Conclusion The AMS scale obviously measures a similar phenomenon as the two established and widely used screeners for androgen deficiency, although it was not developed as a screening instrument.  相似文献   
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What's an Oscar worth?   总被引:9,自引:0,他引:9  
This article examines the impact of an Academy Award nomination and award for best picture, best actor/actress, and best supporting actor/actress on a film's (i) market share of theaters, (ii) average revenue per screen, and (iii) its probability of survival. The model is estimated using weekly box-office data for a matched sample of nominated and non-nominated films. The results indicate substantial financial benefits for a nomination and award for best picture and best actor/actress. The structure of rewards is consistent with that found in two-stage, single-elimination tournaments.  相似文献   
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A report of a new technique of male contraception involves the use of heat which lowers the sperm count. Early reports of lowered sperm counts in men wearing jockstraps or increased sperm counts in men whose testicles have been cooled several degrees have led to the experimentation in the male rat of the effects of heat and ultrasound on the sperm count and the ability to fertilize the female. 250 male rats were divided into 5 groups: 1) control, 2) a 60 degree C water circulating testicle cup with 15 minutes exposure, 3) exposure to radiant energy for 15 minutes and raising scrotal temperatures to 60 degrees C, 4) exposure to microwaves of varying powers, and 5) exposure to ultrasound of 1 w/cm to 2 w/cm for 1 minute. Group 2 results indicated that libido was uninhibited, testosterone levels undisturbed a nd organ sizes unaffected by the hot-water treatment. It took 30-35 days for any pregnancies to occur after a single treatment. In group 3, results were substantially the same except that it took 60-75 days for any pregnancies to occur. In group 4, a 20% exposure to radiation for 5 minutes impaired fertility for 65-80 days, while those exposed to 20% for 15 minutes were still infertile at the end of the 10-month study. In these cases libido was also unimpaired. Animals in group 5, exposed to 1 w/cm for 1 minute had impaired fertility for 150-210 days although testicular temperature rose to only 38 degrees C. When exposure to ultr asound was doubled, fertility was impaired throughout the study. In all cases where fertility was restored, resulting offspring appeared normal and were themselves capable of reproducing normal-appearing offspring. Ultrasound was considered the most promising heat source. In all cases the germinal epithelium function is arrested. Future research should be directed to making the ultrasound technique more finely tuned to a contraceptive function.  相似文献   
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