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A study in the educators' work station at baby nursery of NDI/UFSC, located in Florianópolis, was conducted using the Work Ergonomic Analysis methodological tool. The demand considered was the educators' physical exhaustion caused by the weight carried when taking care of the babies, the postures assumed during the labor activity and the spatial arrangement of the baby nursery. Thinking ergonomically, the spatial arrangement is directly associated to three factors: the formal aspect of the environment, the esthetic aspect including colors and finish quality and the ease of understanding involved in the baby nursery labor. By the ergonomic adequacy it is possible to assert that if were established better conditions of posture and comfort for the educators, as well as satisfactory technical and operational information to carry out the activities, greater safety and welfare would be provided to the babies, the main focus of the work.  相似文献   
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\(\alpha \)-Stable distributions are a family of probability distributions found to be suitable to model many complex processes and phenomena in several research fields, such as medicine, physics, finance and networking, among others. However, the lack of closed expressions makes their evaluation analytically intractable, and alternative approaches are computationally expensive. Existing numerical programs are not fast enough for certain applications and do not make use of the parallel power of general purpose graphic processing units. In this paper, we develop novel parallel algorithms for the probability density function and cumulative distribution function—including a parallel Gauss–Kronrod quadrature—, quantile function, random number generator and maximum likelihood estimation of \(\alpha \)-stable distributions using OpenCL, achieving significant speedups and precision in all cases. Thanks to the use of OpenCL, we also evaluate the results of our library with different GPU architectures.  相似文献   
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Abstract

This paper aims at examining the trends, challenges and theoretical gaps in the implementation of Healthcare 4.0 (H4.0) based on a scoping review of the literature. For that, we searched journal articles in four widely known databases and screened the retrieved articles to obtain a publications’ portfolio. Our findings indicate that, despite the recency of the subject, research in H4.0 has been conducted in an interdisciplinary way with a diversified set of applications and functionalities. In terms of its implementation, H4.0 has been more commonly found in hospitals’ information flows, especially the ones related to healthcare treatments. The identified implementation trends, however, neglect a more holistic approach for H4.0, which originated three main research directions for this topic. Although identified as a trending topic in the area of healthcare operations management, literature on H4.0 may be viewed as randomly conceived, lacking academic alignment and practical orientation based on a grounded theory, which we aim at providing with the present study.  相似文献   
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Michael Polanyi’s defense of freedom in science and society conflicts in major ways with Weber (process of rationalization, value neutrality of sociologists), Popper (objective knowledge, open society), and technological or oppositional sociology. Polanyi rejects positivism, utilitarianism, and Marxism, and defends freedom as a necessary condition for pursuit of spiritual ideals such as truth, justice, charity, and tolerance. Half truths about science seen as rejecting tradition, faith, authority, values, and the subjective, have helped bring valuable social results, but in the form taken by radical philosophical skepticism (doubt), also called objectivism, they also threaten freedom itself. A more truthful account is needed. Scientists and citizens who would maintain a free society are morally responsible persons, joined together in quest of truth and certain other ideals, demanding of themselves and each other that they be faithful to that quest. Polanyi’s thought has connections with that of Shils, and has implications for what Shils calls a consensual sociology. Louis H. Swartz teaches law, and is interested in the development of sociological theory and legal sociology, building upon the contributions of Polanyi and Shils.  相似文献   
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This article reviews a range of issues associated with the commercialization of biomedical research and speculates on how these issues might apply to the neuroscience context. Drawing on existing studies of the impact of research commercialization activities on various areas of biotechnology research, the authors explore normative benchmarks for assessing and resolving issues likely to arise from the commercialization of neuroscientific research, including such topics as patenting, marketing pressures, and representations of research prospects.  相似文献   
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Putting aside whether diseases that affect only small numbers of people (“rare diseases”) should be prioritized over diseases that are otherwise orphaned, in this article I argue that a new approach to rare, orphan diseases is needed. The current model, first signaled by the United States' Orphan Drug Act and subsequently emulated by several other jurisdictions, relies on a set of open-ended criteria and market-based incentives in order to define and encourage drug therapies for rare, orphan diseases. Given a) the biopharmaceutical industries' growing interest in orphan diseases, b) progress in the sphere of personalized medicines enabling more and more common diseases to be reclassified as rare, and c) empirical evidence suggesting that the most orphan drugs target only a limited, lucrative subset of rare diseases, I argue that Canada, which recently announced plans to develop its own “orphan drug framework” should not follow the United States' orphan drug model.  相似文献   
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The decade of the 1980s has witnessed an explosion in legalized gambling. Most dramatic has been the growth of state-sponsored lotteries. The spread of these state-operated lotteries is the result of pressure for more revenues for state operating costs. Lotteries are viewed as a means of raising these revenues: In 1987, state-operated lotteries grossed over $12 billion in sales. Eight states had sales exceeding $1 billion (New York Times, 1988). Clearly, state lotteries have become big business. The purpose of this article is to describe the spread of lotteries in the 1980s and to note the minimal attention given to compulsive gambling in debates on lotteries.Mr. Braidfoot is General Counsel for the Christian Life Commission of the Southern Baptist Convention. He is the author ofGambling: The Deadly Game.  相似文献   
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