Bayesian analysis of human movement curves

Summary.  We consider the Bayesian analysis of human movement data, where the subjects perform various reaching tasks. A set of markers is placed on each subject and a system of cameras records the three-dimensional Cartesian co-ordinates of the markers during the reaching movement. It is of interest to describe the mean and variability of the curves that are traced by the markers during one reaching movement, and to identify any differences due to covariates. We propose a methodology based on a hierarchical Bayesian model for the curves. An important part of the method is to obtain identifiable features of the movement so that different curves can be compared after temporal warping. We consider four landmarks and a set of equally spaced pseudolandmarks are located in between. We demonstrate that the algorithm works well in locating the landmarks, and shape analysis techniques are used to describe the posterior distribution of the mean curve. A feature of this type of data is that some parts of the movement data may be missing—the Bayesian methodology is easily adapted to cope with this situation.     

Familial spinal shape

It has been proposed that there is a familial relationship in the shape of the spine. This paper describes a pilot study investigating familial shape in the sagittal plane (side view), using three data sets of normal Leeds schoolchildren. The study is exploratory in nature, because only small samples were available. Data acquisition was by means of the Quantec system, which obtains surface shape measurements and extracts a line representing the spinal curve. The coordinates of the spine line in the sagittal plane are then used to investigate familial correlations of spinal shape. The spine lines first undergo some preprocessing, including Procrustes rotations to remove location, rotation and size effects. Smoothed principal component analysis of the curves provides suitable shape variables, and familial correlations between curves are then investigated. The covariates of sex and height are also investigated in the analysis. It does appear that there could be some evidence for familial correlations in sagittal spinal shape, although a further large-scale study is required. Finally, a discussion of the approach and other alternatives is considered.     

Review of the use of context in statistical image analysis

SUMMARY This paper is a review of the use of contextual information in statistical image analysis. After defining what we mean by 'context', we describe the Bayesian approach to high-level image analysis using deformable templates. We describe important aspects of work on character recognition and syntactic pattern recognition; in particular, aspects of the work which are relevant to scene understanding. We conclude with a review of some work on knowledge-based systems which use context to aid object recognition.     

Procrustes shape analysis of triangulations of a two coloured point pattern

Consider a set of points in the plane with Gaussian perturbations about a regular mean configuration in which a Delaunay triangulation of the mean of the process is comprised of equilateral triangles of the same size. The points are labelled at random as black or white with variances of the perturbations possibly dependent on the colour. By investigating triangle subsets (with four sets of possible colour labels for the vertices) in detail we propose various test statistics based on a Procrustes shape analysis. A simulation study is carried out to investigate the relative merits and the adequacy of the approximations used in the distributional results, as well as a comparison with simulation methods based on nearest-neighbour distances. The methodology is applied to an investigation of regularity in human muscle fibre cross-sections.     

Healthy relationship education for dating violence prevention among high-risk youth

A federal grant was awarded to provide the Love U2 healthy relationship curriculum to low-income, high-risk youth. This research sought to examine the relative effectiveness of a brief intervention with this curriculum compared to the much more intensive relationship education programs that have been previously provided to high-risk youth. Data were collected from 233 participants through measures of training and relationship outcomes pre- and post-training. Participants experienced high levels of training satisfaction, significant increases in relationship knowledge and self-efficacy related to conflict resolution. They also experienced a significant improvement in attitudes toward couple violence in the desired direction. Implications of these findings for promoting healthy relationships and reducing dating violence among high-risk youth are discussed.     

Extreme shape analysis

Summary.  We consider the analysis of extreme shapes rather than the more usual mean- and variance-based shape analysis. In particular, we consider extreme shape analysis in two applications: human muscle fibre images, where we compare healthy and diseased muscles, and temporal sequences of DNA shapes from molecular dynamics simulations. One feature of the shape space is that it is bounded, so we consider estimators which use prior knowledge of the upper bound when present. Peaks-over-threshold methods and maximum-likelihood-based inference are used. We introduce fixed end point and constrained maximum likelihood estimators, and we discuss their asymptotic properties for large samples. It is shown that in some cases the constrained estimators have half the mean-square error of the unconstrained maximum likelihood estimators. The new estimators are applied to the muscle and DNA data, and practical conclusions are given.     

Regularisation,interpolation and visualisation of diffusion tensor images using non-Euclidean statistics

Practical statistical analysis of diffusion tensor images is considered, and we focus primarily on methods that use metrics based on Euclidean distances between powers of diffusion tensors. First, we describe a family of anisotropy measures based on a scale invariant power-Euclidean metric, which are useful for visualisation. Some properties of the measures are derived and practical considerations are discussed, with some examples. Second, we discuss weighted Procrustes methods for diffusion tensor imaging interpolation and smoothing, and we compare methods based on different metrics on a set of examples as well as analytically. We establish a key relationship between the principal-square-root-Euclidean metric and the size-and-shape Procrustes metric on the space of symmetric positive semi-definite tensors. We explain, both analytically and by experiments, why the size-and-shape Procrustes metric may be preferred in practical tasks of interpolation, extrapolation and smoothing, especially when observed tensors are degenerate or when a moderate degree of tensor swelling is desirable. Third, we introduce regularisation methodology, which is demonstrated to be useful for highlighting features of prior interest and potentially for segmentation. Finally, we compare several metrics in a data set of human brain diffusion-weighted magnetic resonance imaging, and point out similarities between several of the non-Euclidean metrics but important differences with the commonly used Euclidean metric.     

The complex Watson distribution and shape analysis

The complex Watson distribution is an important simple distribution on the complex sphere which is used in statistical shape analysis. We describe the density, obtain the integrating constant and provide large sample approximations. Maximum likelihood estimation and hypothesis testing procedures for one and two samples are described. The particular connection with shape analysis is discussed and we consider an application examining shape differences between normal and schizophrenic brains. We make some observations about Bayesian shape inference and finally we describe a more general rotationally symmetric family of distributions.     

Single-Session One-At-A-Time Therapy: A Personal Approach

The terms ‘Single-Session Therapy’ (SST) and ‘One-At-A-Time’ (OAAT) therapy are both used to indicate a situation where the therapist and client set out with the expressed intention of helping the client in one session while acknowledging that additional sessions are available to the client. Both terms have their advantages and disadvantages and thus the author uses the blended term ‘Single-Session One-At-A-Time’ (SST/OAAT) therapy to highlight the advantages of both. It is a core feature of SST/OAAT therapy that it is client-centred especially where the session’s focus and goal are concerned. However, in an attempt to avoid SST/OAAT therapy being highjacked by therapists who operate from the ‘expert’ source of influence, the field has downplayed the contribution of the therapist’s expertise. In this paper, I make clear that the expertise of the therapist when allied to the expertise of the client can be a potent force for good in SST/OAAT therapy. My main task, however, is to outline my own approach to SST/OAAT therapy which is a blend of general principles that are likely to be held by the majority of SST/OAAT therapist and specific ideas that are derived from working alliance theory, pluralism and Rational Emotive Behaviour Therapy.