Sample Size and Power Calculation in Comparing Diagnostic Accuracy of Biomarkers with Pooled Assessments

When testing of a biomarker is costly, pooling of samples becomes a useful and efficient alternative (Faraggi et al., 2003). In this paper, we develop procedures for sample size and power calculations for planning a study comparing the accuracy of biomarkers in diagnosis of diseases with pooled samples. Explicit formulas are derived for several important pooling strategies. The effects of pooling samples on sample size and power of the test are also discussed.     

Eliciting Accounts of Alleged Child Sexual Abuse: How Do Children Report Touch?

Investigative interviewers frequently question alleged victims of child sexual abuse about any touching or bodily contact that might have occurred. In the present study of forensic interviews with 192 alleged sexual abuse victims, between 4 and 13 years of age, we examined the frequency with which alleged victims reported bodily contact as “touch” and the types of prompts associated with “touch” reports. Even young alleged victims of sexual abuse reported bodily contact as “touch,” and they used the word “touch” more frequently in response to recall than recognition prompts. Regardless of age, children typically referred to “touch” before interviewers used this term, suggesting that even young children are able to report “touch” without being cued by interviewers.     

“Aging males” symptoms and general health of adult males: a cross-sectional study

A cross-sectional study was conducted to explore the prevalence and severity of health-related complaints perceived by adult males of Hong Kong by using the Hong Kong Traditional Chinese versions of the Aging males’ symptoms (AMS) scale and the 5-dimensional and 3-level European Quality of life (EQ-5D-3L) questionnaire. A total of 825 adult males aged 40 years or above were surveyed, and observed that 80% of the population was living with little-to-mild levels of aging symptoms with mean total scores ranged between 26.02?±?7.91 and 32.99?±?7.91 in different age groups. Such symptoms were correlated with age, especially for the somato-vegetative and sexual symptoms. The most severe AMS symptoms were observed in the oldest age group at 70 years or above, with 76%, 34% and 70% living with moderate-to-severe levels of somato-vegetative, psychological and sexual symptoms, respectively. The result was highly correlated with the EQ-5D-3L questionnaire. Secondly, the Hong Kong Aging males’ symptoms (AMS) scale was shown to have good reliability with test–retest coefficient at 0.79 (ranged 0.66–0.87) and Cronbach’s alpha coefficient at 0.88 (ranged 0.70–0.84). In summary, the population of Hong Kong male adults was commonly living with little-to-mild levels of aging symptoms, whereas their severity was correlated with age.     

A Study on EWMA charts with runs rules—the Markov chain approach

ABSTRACT

Runs rules are usually used with Shewhart-type charts to enhance the charts' sensitivities toward small and moderate shifts. Abbas et al. in 2011 took it a step further by proposing two runs rules schemes, applied to the exponentially weighted moving average (EWMA) chart and evaluated their average run length (ARL) performances using simulation. They showed that the proposed schemes are superior to the classical EWMA chart and other schemes being investigated. Besides pointing out some erroneous ARL and standard deviation of the run length (SDRL) computations in Abbas et al., this paper presents a Markov chain approach for computing the ARL, percentiles of the run length (RL) distribution and SDRL, for the two runs rules schemes of Abbas et al. Using Markov chain, we also propose two combined runs rules EWMA schemes to quicken the two schemes of Abbas et al. in responding to large shifts. The runs rules (basic and combined rules) EWMA schemes will be compared with some existing control charting methods, where the former charts are shown to prevail.     

Executive functioning in Asian pathological gamblers

Two decades of neuropsychological research on predominantly Caucasian problem gamblers has unveiled significantly poorer performance on several domains of executive functioning (EF) relative to healthy controls. However, contradictory findings are widespread and evidence that pathological gamblers (PGs) are ‘impaired’ remains inconclusive. The study examined multiple facets of EF in 30 male, PGs seeking outpatient treatment in Singapore and 30 matched controls. CANTAB® tests of planning and organization/problem-solving, set-shifting, working memory and reflection impulsivity, were administered alongside the Barratt Impulsiveness Scale, Cognitive Failures Questionnaire and Dysexecutive Questionnaire. No significant group differences were found on any of the EF performance parameters, with performance falling in the healthy, unimpaired range for both groups. PGs did, however, report significantly greater impulsivity, everyday cognitive failures and symptoms of the dysexecutive syndrome. Exploratory analysis on a subgroup of PGs addicted to non-strategic gambling activities revealed poorer EF performance than among those addicted to strategic gambling activities. The findings suggest an absence of EF deficits despite higher trait impulsivity in Asian, predominantly strategic PGs. Hence, psychological interventions such as CBT and treatment approaches that emphasize the use of self-monitoring and informed decision-making to reduce impulsive behaviours should be suited to this population.     

The financial burden of psychosocial workplace aggression: A systematic review of cost-of-illness studies

Understanding the economic impact of psychological and social forms of workplace aggression to society could yield important insights into the magnitude of this occupational phenomenon. The objective of this systematic review was to collate, summarise, review and critique, and synthesise the cost of psychosocial workplace aggression at the individual- and societal-level. A peer-reviewed research protocol detailing the search strategy, study selection procedures and data extraction process was developed a priori. Both the academic and grey literatures were examined. To allow for basic comparison, all costs were converted and adjusted to reflect 2014 US dollars. Twelve studies, from 5 national contexts, met the inclusion criteria and were reviewed: Australia (n?=?2), Italy (n?=?1), Spain (n?=?1), the United Kingdom (n?=?3) and the United States (n?=?5). The annual cost of psychosocial workplace aggression varied substantially, ranging between $114.64 million and $35.9 billion. Heterogeneity across studies was found, with noted variations in stated study aims, utilised prevalence statistics and included costs. The review concludes that existing evidence attests to the substantial cost of psychosocial workplace aggression to both the individual and society, albeit such derived estimates are likely gross under-estimates. The findings highlight the importance of interpreting such figures within their conceptual and methodological contexts.     

The historicization of nostalgia,locality and quotidianity: on the changes in Lim Kim Chern’s gastronomic writing

This article seeks to shed light on Lim Kim Chern’s gastronomic writing, by ensconcing this individual case in the context of Modern Chinese Prose as an enduring literary tradition, in order to elicit the attribute of locality with diasporic discourse in quotidian life, that distinguishes it as part of a work in Malaysian Chinese Literature than the others. We will further this quest, by comparing the gastronomic writing of Lim before and after the changes in his literary pursuit in gastronomic writing, namely, by the comparison of the literary hierarchy of high-brow literature and the sub-genre of literature that post-positions the literariness, in order to examine whether or not it is a revelation, or even a harbinger of the fate of Malaysian Chinese Literature being minor literature.     

Self-Concept,Attitudes Toward Career Counseling,and Work Readiness of Malaysian Vocational Students

The authors examined the relationship between self-concept, attitudes toward career counseling, and work readiness among 574 Malaysian vocational students. Attitudes toward career counseling have been studied in Western cultures; however, little is known about how career counseling is perceived in Eastern cultures. Attitudes toward career counseling were examined as a potential mediator of the relationship between self-concept and work readiness. The authors applied structural equation modeling to explain these relationships. Value of career counseling was found to significantly mediate the link between self-concept and work readiness. Results supported a direct relationship between positive self-concept and work readiness skills. This may be due, in part, to a heightened value of career counseling among vocational students that increases career awareness and thus enhances work readiness. Future research could include samples with more female participants and additional constructs, such as self-efficacy and career adaptability.