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Background: Sarcopenia is a pathophysiological condition diffused in elderly people; it represents a social issue due to the longer life expectancy and the growing aging population. It affects negatively quality of life and it represents a risk factor for other pathologies, such as diabetes, cardiovascular disease, and obesity. No silver bullet exists to hinder sarcopenia, but it may be counteracted by physical exercise, nutrition, and a proper endocrine milieu. Indeed, we aim to analyze the scientific literature to give to clinician effective advices to counteract sarcopenia.

Main text: Physical exercise, proper nutrition, optimized hormonal homeostasis represent the three pillars to fight sarcopenia. Physical exercise represents the most effective remedy to face sarcopenia, in particular if it is combined with a proper diet and with an adequate endocrine milieu. Consistency in training, adequate daily protein intake and eugonadism seems to be the keys to fight sarcopenia. The combination of these three pillars might act synergistically.

Conclusions: Optimization of these factors may increase their efficiency; however, scientific data may be sometimes confusing so far. Therefore, we aim to give practical advices to clinician to identify and to highlight the most important aspects in each of these three factors that should be addressed.  相似文献   

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When technological change affects the prices of tradeable assets, innovators can obtain speculative profits by exploiting their inside information as to the occurrence of innovations. We propose a tractable model of endogenous growth that formalizes this argument, originally due to Hirshleifer (1971). We then use the model to assess two claims advanced by Hirshleifer, namely, that speculative profits can generate excessive investment in R&D when they add to monopoly rents guaranteed by patent protection, or else even in a perfectly competitive economy. The analysis confirms the first claim, but casts doubts on the second one. (JEL O30, O40)  相似文献   
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This study focuses on the issues relating to the implementation of management accounting systems in complex settings such as archeological sites. The aim is to understand the conditions under which the implementation of performance management systems (PMS) may enable cultural organizations to fulfil their multiple objectives and the factors which play a crucial role in such dynamics. Focusing on the Herculaneum Conservation Project (HCP) the study explains how PMS came to be implemented having been made acceptable to all parties involved. The Middle Range Theory as developed by Broadbent and Laughlin (Accounting control and controlling accounting: interdisciplinary and critical perspectives, Bingley, Emerald, 2013) was utilized to explore how the PMS change took place in the HCP, and focus on the factors influencing this process. The findings reveal that the change in the PMS benefited from the involvement of a multidisciplinary Specialist Work Group. This involvement reduced the natural tendency to resist the forces of change and increased the commitment of the various groups of stakeholders to the new culture. The findings reveal how PMS were developed in the context of a multifaceted approach to change, allowing us to draw both theoretical and practical lessons that may be brought to bear in other complex contexts.  相似文献   
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In literature, several variables, both individual and collective level, have been utilized to explain community engagement: the active, voluntary involvement of individuals and groups in changing problematic conditions in communities. The purpose of this study is to identify the main community-based variables and, via meta-analysis research, calculate the effects of these variables on community engagement. These variables include sense of community, community identity, social well-being, place identity, trust in the community, trust in institutions, and community cohesion. The overall and partial effect sizes and heterogeneity between studies were calculated. Some study characteristics (i.e. type of sample, size of sample, percentage of women in the sample, and mean age) were used as moderators for subsample analysis and meta-regressions. The first six major variables (sense of community, community identity, social well-being, place identity, trust in the community, and trust in institutions) show a positive but moderate relationship with community engagement. As for the moderating variables were not found substantial variations. The data are very heterogeneous and highlight the complex and multivariate nature of community engagement. Theoretical and methodological implications were discussed.  相似文献   
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In this article we outline and demonstrate a design anthropological approach to investigating automated mobile futures as a processual opening up of possibilities, rather than as a process of technological innovation. To undertake this we investigate the example of how the car-smartphone relationship is configuring in the contingent circumstances of the mobile present and the implications of this for automated mobile futures. Our discussion is set in the context of the growing possibility that automonous driving (AD) features are increasingly part of everyday mobilities (even if unequally distributed globally) and in which personal mobile smart technologies and artificial intelligence (AI) will exist in some form and will interface with humans and be interoperable with other technologies. In developing this we draw on ethnographic understandings of how people live with the possibilities afforded by technologies in everyday life.  相似文献   
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There are several forest operations involved in Eucalyptus timber harvesting. This study was carried out during brush-cutting; tree felling, bucking, delimbing, piling and manual extraction operations, with the following objectives: a) analyzing, ergonomically, two systems of brush-cutting: one manual and the other semi-mechanized, using two different machines; b) ergonomically evaluating three different brands of pruner machines used in delimbing felled trees. c) determining the feasible target of productivity as a function of ergonomic factors relevant to establish the time of resting pauses for workers in manual and semi-mechanized timber harvesting systems in mountainous terrain. Brush-cutting, either manual or semimechanized, is an activity carried out prior to timber harvesting. It is usually a hard work, with low productivity when compared with mechanized systems. Pruner machines have been used by forest companies, due to the great possibilities to improve productivity, quality and the health of workers. Ergonomics is a discipline that promotes the adequacy of work to the physical and mental characteristics of human beings, seeking to design production systems and products considering relevant aspects, including social, organizational and environmental factors. Companies should consider the ergonomic factor in the determination of daily worker production targets.  相似文献   
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