Joint models for mixed categorical outcomes: a study of HIV risk perception and disease status in Mozambique

Two types of bivariate models for categorical response variables are introduced to deal with special categories such as ‘unsure’ or ‘unknown’ in combination with other ordinal categories, while taking additional hierarchical data structures into account. The latter is achieved by the use of different covariance structures for a trivariate random effect. The models are applied to data from the INSIDA survey, where interest goes to the effect of covariates on the association between HIV risk perception (quadrinomial with an ‘unknown risk’ category) and HIV infection status (binary). The final model combines continuation-ratio with cumulative link logits for the risk perception, together with partly correlated and partly shared trivariate random effects for the household level. The results indicate that only age has a significant effect on the association between HIV risk perception and infection status. The proposed models may be useful in various fields of application such as social and biomedical sciences, epidemiology and public health.     

A flexible semiparametric regression model for bimodal,asymmetric and censored data

In this paper, we propose a new semiparametric heteroscedastic regression model allowing for positive and negative skewness and bimodal shapes using the B-spline basis for nonlinear effects. The proposed distribution is based on the generalized additive models for location, scale and shape framework in order to model any or all parameters of the distribution using parametric linear and/or nonparametric smooth functions of explanatory variables. We motivate the new model by means of Monte Carlo simulations, thus ignoring the skewness and bimodality of the random errors in semiparametric regression models, which may introduce biases on the parameter estimates and/or on the estimation of the associated variability measures. An iterative estimation process and some diagnostic methods are investigated. Applications to two real data sets are presented and the method is compared to the usual regression methods.     

New regression model with four regression structures and computational aspects

A new general class of exponentiated sinh Cauchy regression models for location, scale, and shape parameters is introduced and studied. It may be applied to censored data and used more effectively in survival analysis when compared with the usual models. For censored data, we employ a frequentist analysis for the parameters of the proposed model. Further, for different parameter settings, sample sizes, and censoring percentages, various simulations are performed. The extended regression model is very useful for the analysis of real data and could give more adequate fits than other special regression models.     

Explaining the demand for structured financial products: survey and field experiment evidence

In many countries structured investment products are popular among retail investors. We explain the demand for these products using unique field data where we let subjects freely design their “favorite” structured product. Results suggest that the supply with capital protected products (guarantee certificates) might indeed be demand-driven. This does not seem to be the case for other product categories where marketing and sales practices might play a more important role. In a survey among financial practitioners we find furthermore that a demand for capital protected products can be explained by loss aversion and saving motifs, e.g. for buying a house.     

Model selection in regression based on pre-smoothing

In this paper, we investigate the effect of pre-smoothing on model selection. Christóbal et al 6 Christóbal Christóbal, J. A., Faraldo Roca, P. and González Manteiga, W. 1987. A class of linear regression parameter estimators constructed by nonparametric estimation. Ann. Statist.,, 15: 603–609. [Crossref], [Web of Science ®] [Google Scholar] showed the beneficial effect of pre-smoothing on estimating the parameters in a linear regression model. Here, in a regression setting, we show that smoothing the response data prior to model selection by Akaike's information criterion can lead to an improved selection procedure. The bootstrap is used to control the magnitude of the random error structure in the smoothed data. The effect of pre-smoothing on model selection is shown in simulations. The method is illustrated in a variety of settings, including the selection of the best fractional polynomial in a generalized linear model.     

Kanban optimization by simulation and evolution

The problem of the optimal design of multistage systems with Kanban control mechanism is investigated. The optimization problem generalizes those from literature by considering a general criterion function and including the lot sizes as decision variables. Since no analytical solutions can be expected simulation combined with a genetic algorithm is used. The simulator KaSimIR as well as the optimization tool LEO are briefly described. Some examples demonstrate the usability of the approach.     

A note on Savage's theorem with a finite number of states

This article gives a preference-based characterization of subjective expected utility for the general equilibrium model with a finite number of states. The characterization follows Savage (1954) as closely as possible but has to abandon his axiom (P6), atomlessness of events, since this requires an infinite state space. To introduce continuity we replace (P6) with a continuity assumption on the set of consequences and assume the preferences are smooth. Then we apply Savage's sure-thing principle and his state-independence axiom to get an additively separable utility representation. Finally, to separate subjective probabilities from basic tastes, we apply a new axiom, which states that for each pair of states the marginal rate of substitution is constant along the certainty line.     

Revealing age-specific past and future unrelated costs of pneumococcal infections by flexible generalized estimating equations

We aimed to study the excess health-care expenditures for persons with a known positive isolate of Streptococcus pneumoniae. The data set was compiled by linking the database of the largest Belgian Sickness Fund with data obtained from laboratories reporting pneumococcal isolates. We analyzed the age-specific per-patient cumulative costs over time, using generalized estimating equations (GEEs). The mean structure was described by fractional polynomials. The quasi-likelihood under the independence model criterion was used to compare different correlation structures. We show for all age groups that the health-care costs incurred by diagnosed pneumococcal patients are significantly larger than those incurred by undiagnosed matched persons. This is not only the case at the time of diagnosis but also long before and after the time of diagnosis. These findings can be informative for the current debate on unrelated costs in health economic evaluation, and GEEs could be used to estimate these costs for other diseases. Finally, these results can be used to inform policy on the expected budget impact of preventing pneumococcal infections.     

Estimating cumulative prospect theory parameters from an international survey

We conduct a standardized survey on risk preferences in 53 countries worldwide and estimate cumulative prospect theory parameters from the data. The parameter estimates show that significant differences on the cross-country level are to some extent robust and related to economic and cultural differences. In particular, a closer look on probability weighting underlines gender differences, economic effects, and cultural impact on probability weighting. The data set is a useful starting point for future research that investigates the impact of risk preferences on the market level.