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1.
In the development of many diseases there are often associated random variables which continuously reflect the progress of a subject towards the final expression of the disease (failure). At any given time these processes, which we call stochastic covariates, may provide information about the current hazard and the remaining time to failure. Likewise, in situations when the specific times of key prior events are not known, such as the time of onset of an occult tumour or the time of infection with HIV-1, it may be possible to identify a stochastic covariate which reveals, indirectly, when the event of interest occurred. The analysis of carcinogenicity trials which involve occult tumours is usually based on the time of death or sacrifice and an indicator of tumour presence for each animal in the experiment. However, the size of an occult tumour observed at the endpoint represents data concerning tumour development which may convey additional information concerning both the tumour incidence rate and the rate of death to which tumour-bearing animals are subject. We develop a stochastic model for tumour growth and suggest different ways in which the effect of this growth on the hazard of failure might be modelled. Using a combined model for tumour growth and additive competing risks of death, we show that if this tumour size information is used, assumptions concerning tumour lethality, the context of observation or multiple sacrifice times are no longer necessary in order to estimate the tumour incidence rate. Parametric estimation based on the method of maximum likelihood is outlined and is applied to simulated data from the combined model. The results of this limited study confirm that use of the stochastic covariate tumour size results in more precise estimation of the incidence rate for occult tumours.  相似文献   
2.
Estimates of adult mortality in countries with limited vital registration (e.g., sub-Saharan Africa) are often derived from information about the survival of a respondent’s siblings. We evaluated the completeness and accuracy of such data through a record linkage study conducted in Bandafassi, located in southeastern Senegal. We linked at the individual level retrospective siblings’ survival histories (SSH) reported by female respondents (n = 268) to prospective mortality data and genealogies collected through a health and demographic surveillance system (HDSS). Respondents often reported inaccurate lists of siblings. Additions to these lists were uncommon, but omissions were frequent: respondents omitted 3.8 % of their live sisters, 9.1 % of their deceased sisters, and 16.6 % of their sisters who had migrated out of the DSS area. Respondents underestimated the age at death of the siblings they reported during the interview, particularly among siblings who had died at older ages (≥45 years). Restricting SSH data to person-years and events having occurred during a recent reference period reduced list errors but not age and date errors. Overall, SSH data led to a 20 % underestimate of 45 q 15 relative to HDSS data. Our study suggests new quality improvement strategies for SSH data and demonstrates the potential use of HDSS data for the validation of “unconventional” demographic techniques.  相似文献   
3.
In this article I map out the major debates on global governance and the feminist critiques of the mainstream interventions in these debates. I argue that the shift from government to governance is a response to the needs of a gendered global capitalist economy and is shaped by struggles, both discursive and material, against the unfolding consequences of globalization. I suggest feminist interrogations of the concept, processes, practices and mechanisms of governance and the insights that develop from them should be centrally incorporated into critical revisionist and radical discourses of and against the concept of global governance. However, I also examine the challenges that the concept of global governance poses for feminist political practice, which are both of scholarship and of activism as feminists struggle to address the possibilities and politics of alternatives to the current regimes of governance. I conclude by suggesting that feminist political practice needs to focus on the politics of redistribution in the context of global governance.  相似文献   
4.
Workplace aggression and violence is the fastest growing societal concerns in USA. The review of literature indicates that violence is a substantial contributor to occupational injuries and death. Preventative strategies for minimizing the risk of workplace violence include, cash-handling policies, physical separation of workers from customers, environmental modifications; good lighting, security devices, escort services, and employee training. Studies also suggest that as a preventive measure, employers will attract and retain the best workers if high-risk behaviors are discouraged and appropriate behaviors are supported. Proactive strategies reduce stress, increase productivity, and enhance creativity. A role for occupational therapy practitioners in the prevention of workplace violence is proposed.  相似文献   
5.
Mortality among neonates has long been largely neglected by research in all developing nations of world including India. This study aims to identify the primary and secondary causes of neonatal deaths among the tribes of Gujarat by retrospectively analyzing 106 neonatal deaths that occurred during the year 2008 and 2009. The socio-economic, biological and traditional newborn care practices impacting newborn survival were also studied. Case studies including in-depth interviews of 33 women who had experienced neonatal deaths in period of 2008 and 2009 have also been conducted. The results show that the main causes of neonatal deaths in the study area were birth asphyxia, prematurity, aspiration, infection and congenital anomalies, irrespective of place of delivery. Absence of trained and skilled personnel for newborn resuscitation was the main cause of perinatal birth asphyxia related deaths. Around 36% mothers had a history of infant deaths. Low birth weight is one of the important causes of neonatal deaths among mothers who had a history of child loss. Cyclicality of neonatal deaths continued among clustered families with social factors initiating the cycle. Qualified trained birth attendants practicing essential newborn care are necessary during home deliveries.  相似文献   
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We consider graph properties that can be checked from labels, i.e., bit sequences, of logarithmic length attached to vertices. We prove that there exists such a labeling for checking a first-order formula with free set variables in the graphs of every class that is nicely locally clique-width-decomposable. This notion generalizes that of a nicely locally tree-decomposable class. The graphs of such classes can be covered by graphs of bounded clique-width with limited overlaps. We also consider such labelings for bounded first-order formulas on graph classes of bounded expansion. Some of these results are extended to counting queries.  相似文献   
8.
This paper is a reflective essay about our experience in conducting a participatory, community self-evaluation of a neighborhood revitalization effort in Milwaukee, Wisconsin. We took a controversial approach to evaluation by focusing on learning community dialogues as a vehicle for program evaluation. As we implemented our strategy, two sets of contradictions surfaced. The first points to the fundamental differences between conventional and constructivist research paradigms. The second centers around our focus on dialogue as a strategy for evaluation. In response to these contradictions we performed three complementary roles: program evaluator, process consultant, and learning facilitator. We are not implying that we performed an outstanding job in these roles. Rather, this article is our way of taking stock of what we learned about our practice as evaluators and how we may expand our repertoire of skills in the future.  相似文献   
9.
In this article I focus on a subaltern approach to knowledge networks by examining the process of setting up such a network, the South Asia Research Network (SARN) on Gender, Law and Governance. I reflect on the construction of discourses about ‘knowledge’ and ‘knowledge–makers’ and the issues of access that emerge as a result of these discourses and practices. I outline three aspects of a ‘politics of network(s)–ing’: the politics of process; the politics of outcome; and the politics of framing. I conclude that the borders of which we need to be aware are not just national borders but also borders of power. Knowledge networks are politically heterogeneous and for subaltern networks to have sustainable organizations as well as critical politics they need to be self–reflective and deliberative.  相似文献   
10.
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