Semiparametric sieve maximum likelihood estimation under cure model with partly interval censored and left truncated data for application to spontaneous abortion

Lifetime Data Analysis - This work was motivated by observational studies in pregnancy with spontaneous abortion (SAB) as outcome. Clearly some women experience the SAB event but the rest do not....     

用Intranet模式改造传统的MIS

讨论了信息技术对企业的影响,指出传统的客户机／服务器模式下的企业管理信息系统的不足之处;分析了Ｉｎｔｒａｎｅｔ对传统的管理信息系统的体系结构所产生的影响;提出了基于浏览器／服务器的Ｉｎｔｒａｎｅｔ管理信息系统结构,该结构由网络应用支撑、信息资源管理、办公应用和事物处理应用四大平台构成。     

企业集团总经理报酬的影响因素分析

企业集团不仅有其特殊的委托代理问题,而且还有与一般公司相同的治理问题,其中总经理的报酬激励是其核心问题之一。笔者把影响总经理报酬的因素分为人力资本因素、企业集团特征因素、公司治理因素及其他因素,分别进行了分析,并建立了影响总经理报酬的多因素模型。     

Estimation of Main Effect When Covariates Have Non-Proportional Hazards

The Cox proportional hazards (PH) regression model has been widely used to analyze survival data in clinical trials and observational studies. In addition to estimating the main treatment or exposure group effect, it is common to adjust for additional covariates using the Cox model. It is well known that violation of the PH assumption can lead to estimates that are biased and difficult to interpret, and model checking has become a routine procedure. However, such checking might focus on the primary group comparisons, and the assumption can still be violated when adjusting for many of the potential covariates. We study the effect of violation of the PH assumption of the covariates on the estimation of the main group effect in the Cox model. The results are summarized in terms of the bias and the coverage properties of the confidence intervals. Overall in randomized clinical trials, the bias caused by misspecifying the PH assumption on the covariates is no more than 15% in absolute value regardless of sample size. In observational studies where the covariates are likely correlated with the group variable, however, the bias can be very severe. The coverage properties largely depend on sample size, as expected, as bias becomes dominating with increasing sample size. These findings should serve as cautionary notes when adjusting for potential confounders in observational studies, as the violation of PH assumption on the confounders can lead to erroneous results.     

路漫漫而上下求索——江苏省特级教师孙双金个案研究

本个案以实地访谈为主的质性研究方法 ,对江苏省小学语文特级教师孙双金进行了研究 ,目的是探究他成长为名教师的规律及机制。研究表明 ,孙双金的成功是由其所处的校本文化、亲身参与的行动研究及其个性倾向特征 3个方面因素所决定的     

农业土壤污染防治的法律法规分析

农为民本,农业土壤污染直接关系着粮食安全,目前我国对于土壤污染并无专门的防治法律出台,而农业土壤污染仅靠《农业法》等几部法律有零星规定远远不够,在执法环节更是问题重重。本文分析相关法律及其不足之处,并提出合理化建议。     

社会群体特征因素对产品设计的影响

基于社会学理论的年龄群体的生理和心理特征,研究中国从40年代以来政治生活的变迁给处于当代的老年人、中年人、青年人造成的文化价值取向特征和行为模式,分析该三类群体在选择产品时的差异。并结合实例说明,基于消费者特征的研究有助于产品设计的目标定位和产品市场的细分,针对不同社会群体的产品设计在为设计师带来市场机会的同时,也满足了人们的消费需求。     

网络语境中大学生价值观的解读

大学生正处于世界观、人生观、价值观成长、成熟阶段,网络对大学生价值观的形成带来了冲击。网络语境中大学生价值观的冲突表现在个体性价值冲突和社会性价值冲突之中,并影响着大学生主体价值观的舒展、民主价值观的彰显和以人为本价值观的追求。     

负荷心肌灌注显像、CT冠脉成像和冠脉造影对可疑冠心病老年患者的诊断价值

目的和方法前瞻性比较50例可疑冠心病患者,经PCI前后MECT、CAG和MPI三种检查方法的阳性率、冠脉狭窄程度和数量、缺血部位和再狭窄的特点。结果MECT与CAG示以中度狭窄较多,二者的阳性率、阴性率、轻中度狭窄的准确性基本一致,CAG在重度狭窄的准确性较高。三种方法PCI前后同等对照狭窄或缺血有显著差异,术前无差异,MPI阳性率低于前二者,可逆性缺血部位行PCI后缺血改善明显好于固定缺损区。再狭窄主要位于支架处,且为软化斑。结论MECT主要用于筛选可疑患者,了解斑块性质及PCI术后是否有再狭窄;MECT阳性者再行MPI了解缺血程度和部位：有可逆缺损者再行CAG和PCI。     

论现代语言学系统思想的历史渊源

系统观作为认识客观世界的一种视角,具有认识论和方法论的普遍意义.本文拟就系统思想形成的历史沿革,对语言学系统思想的历史渊源作一些探讨.文章最后的结论是,语言学系统思想的发展与系统思想本身的发展紧密相关,用系统的思想考察复杂的语言现象既必要又合理.