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1.
This paper takes a sociometric approach to the process of skills formation in children as they mature into adults. Honda suggests that meaningful communication with family as a child is the determining factor that raises those abilities (ability β 1 ) that fall outside of scholastic aptitude – motivation, personal relations skills, personality, and emotions. Along with considering the results of Honda's thesis, I have constructed an operating hypothetic model that includes two additional factors: the financial state of the family during childhood, and the transition of the communication target from within the family to a target outside the family. The data for this investigation were then verified. From the results, the direct effect of the observed family communication, when isolated from other influencing variables in the formation of abilities β, is not as decisive a factor as Honda emphasized. It was clear that the financial status of the family played a role, as did the indirect results of the intermediary shift from communication within the family to outside the family (the process of children becoming socially independent). The results of this analysis show that we should not necessarily be looking for the decisive factors of abilities β within the family; if anything, it reflects the existence of a formative route for abilities β that capitalizes on the resources outside the family. Based on the above, the results also show the potential for the introduction of social intervention to address the disparity and inequality in skills formation, and the possible anticipation of more rationality in the overblown discourse surrounding the role of the family in facilitating educational ability.  相似文献   
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Randomized phase II selection trials seek to provide unbiased comparisons for the selection of the most promising treatment arm for evaluation in a future phase III trial. In this paper, we present an application of an adaptive design to a randomized phase II selection trial comparing three experimental treatments with a control arm in patients with advanced gastric cancer. The trial design continuously monitors multiple patient outcomes to protect future patients from treatments with unacceptably high toxicity and/or unacceptably low efficacy. We use a Bayesian approach to monitor the trial and carry out simulations to investigate operating characteristics of the trial design. The simulation study also evaluates the sensitivity of the design to the prior distribution by considering two alternative priors.  相似文献   
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Patient heterogeneity may complicate dose‐finding in phase 1 clinical trials if the dose‐toxicity curves differ between subgroups. Conducting separate trials within subgroups may lead to infeasibly small sample sizes in subgroups having low prevalence. Alternatively,it is not obvious how to conduct a single trial while accounting for heterogeneity. To address this problem,we consider a generalization of the continual reassessment method on the basis of a hierarchical Bayesian dose‐toxicity model that borrows strength between subgroups under the assumption that the subgroups are exchangeable. We evaluate a design using this model that includes subgroup‐specific dose selection and safety rules. A simulation study is presented that includes comparison of this method to 3 alternative approaches,on the basis of nonhierarchical models,that make different types of assumptions about within‐subgroup dose‐toxicity curves. The simulations show that the hierarchical model‐based method is recommended in settings where the dose‐toxicity curves are exchangeable between subgroups. We present practical guidelines for application and provide computer programs for trial simulation and conduct.  相似文献   
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In this paper, we introduce the new workflow line system consisted of the location and image recording, which led to the acquisition of workflow information and the analysis display. From the results of workflow line investigation, we considered the anticipated effects and the problems on KAIZEN. Workflow line information included the location information and action contents information. These technologies suggest the viewpoints to help improvement, for example, exclusion of useless movement, the redesign of layout and the review of work procedure. Manufacturing factory, it was clear that there was much movement from the standard operation place and accumulation residence time. The following was shown as a result of this investigation, to be concrete, the efficient layout was suggested by this system. In the case of the hospital, similarly, it is pointed out that the workflow has the problem of layout and setup operations based on the effective movement pattern of the experts. This system could adapt to routine work, including as well as non-routine work. By the development of this system which can fit and adapt to industrial diversification, more effective "visual management" (visualization of work) is expected in the future.  相似文献   
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The objective of this article was to propose an exposure assessment model to describe the relationship between fish consumption and body methyl mercury (MeHg) levels in the Japanese population. Individual MeHg intake was estimated by the summation of species-specific fish consumption multiplied by species-specific fish MeHg levels. The distribution of fish consumed by individuals and the MeHg level in each fish species were assigned based on published data from Japanese government institutions. The probability of MeHg intake for a population was accomplished through a Monte Carlo simulation by the random sampling of fish consumption and species-specific MeHg levels. Internal body MeHg levels in blood and hair were estimated using a one-compartment model. Overall, the mean value of MeHg intake for the Japanese population was estimated to be 6.76 μg/day or 0.14 μg/kg body weight per day (bw/day), while the mean value for the hair mercury level was 2.02 μg/g. Compared with the survey data that tabulated hair mercury levels in a cross-section of the Japanese population, the simulation results matched the hair mercury survey data very well for women, but somewhat underestimated for men and all of the population. This exposure assessment model is a useful attempt at further risk assessment with respect to a risk-benefit analysis.  相似文献   
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A long tradition in stratification research argues students with higher cultural capital are likely to be treated by their teachers as possessing the “right culture,” which positively affects their academic performance. Nevertheless, the literature has paid little attention to the role of students' perception in this process. Using two waves of the China Educational Panel Survey, we investigate how students' cultural capital affects their own understanding of teacher-student interactions, including its gender difference. Fixed effects regressions show a substantially positive effect of cultural capital on the perceived frequency of teachers praising and calling on students to answer questions across subjects. Nonetheless, we also find the lack of cultural capital is not punished and that the cultural capital's effect varies across its specific components and gender. These findings pave the way for elucidating the entire causal chain of intergenerational social inequality via cultural capital, teacher bias, students’ perception, and their educational outcomes.  相似文献   
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Age at first union is increasing throughout much of sub-Saharan Africa at the same time that not all couples are waiting for marriage before their first sexual intercourse. We assessed the effect of a premarital first birth on entrance into a first union in an urban area in East Africa—Moshi, Tanzania. The data come from the Moshi Infertility Survey of 2002–2003. Women who spent less than a year in single motherhood were significantly more likely than childless women to enter into a first union, although the magnitude of this relationship was weaker for more recent cohorts. Women who had been single mothers for 5 or more years (about two-thirds of women with a premarital birth) were significantly less likely than women without children to enter into a first union.  相似文献   
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This paper expands on Kingsley Davis’s demographic thesis of change and response. Specifically, we consider the social context that accounts for the primacy of particular birth control methods that bring about fertility change during specific time periods. We examine the relevance of state policy (including national family planning programs), the international population establishment, the medical profession, organized religion, and women’s groups using case studies from Japan, Russia, Puerto Rico, China, India, and Cameroon. Some of these countries are undergoing the second demographic transition, others the first. Despite variations in context, heavy reliance on sterilization and/or, abortion as a means of birth control is a major response in most of these countries. The key roles of the medical profession and state policy are discussed, along with the general lack of influence of religion and of women’s groups in these countries.  相似文献   
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