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排序方式: 共有90条查询结果,搜索用时 31 毫秒
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Casey Crump Kenny Crump Eric Hack Rose Luippold Kenneth Mundt Elizabeth Liebig Julie Panko Dennis Paustenbach Deborah Proctor 《Risk analysis》2003,23(6):1147-1163
This study evaluates the dose-response relationship for inhalation exposure to hexavalent chromium [Cr(VI)] and lung cancer mortality for workers of a chromate production facility, and provides estimates of the carcinogenic potency. The data were analyzed using relative risk and additive risk dose-response models implemented with both Poisson and Cox regression. Potential confounding by birth cohort and smoking prevalence were also assessed. Lifetime cumulative exposure and highest monthly exposure were the dose metrics evaluated. The estimated lifetime additional risk of lung cancer mortality associated with 45 years of occupational exposure to 1 microg/m3 Cr(VI) (occupational exposure unit risk) was 0.00205 (90%CI: 0.00134, 0.00291) for the relative risk model and 0.00216 (90%CI: 0.00143, 0.00302) for the additive risk model assuming a linear dose response for cumulative exposure with a five-year lag. Extrapolating these findings to a continuous (e.g., environmental) exposure scenario yielded an environmental unit risk of 0.00978 (90%CI: 0.00640, 0.0138) for the relative risk model [e.g., a cancer slope factor of 34 (mg/kg-day)-1] and 0.0125 (90%CI: 0.00833, 0.0175) for the additive risk model. The relative risk model is preferred because it is more consistent with the expected trend for lung cancer risk with age. Based on statistical tests for exposure-related trend, there was no statistically significant increased lung cancer risk below lifetime cumulative occupational exposures of 1.0 mg-yr/m3, and no excess risk for workers whose highest average monthly exposure did not exceed the current Permissible Exposure Limit (52 microg/m3). It is acknowledged that this study had limited power to detect increases at these low exposure levels. These cancer potency estimates are comparable to those developed by U.S. regulatory agencies and should be useful for assessing the potential cancer hazard associated with inhaled Cr(VI). 相似文献
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Historically, women’s sexual desire has been deemed socially problematic. The growing popularity of the concept of hypersexuality—which lists high sexual desire among its core components—poses a risk of re-pathologizing female sexual desire. Data from a 2014 online survey of 2,599 Croatian women aged 18–60 years was used to examine whether high sexual desire is detrimental to women’s relationship and sexual well-being. Based on the highest scores on an indicator of sexual desire, 178 women were classified in the high sexual desire (HSD) group; women who scored higher than one standard deviation above the Hypersexual Disorder Screening Inventory mean were categorized in the hypersexuality (HYP) group (n = 239). Fifty-seven women met the classification criteria for both groups (HYP&HSD). Compared to other groups, the HSD was the most sexually active group. Compared to controls, the HYP and HYP&HSD groups—but not the HSD group—reported significantly more negative consequences associated with their sexuality. Compared to the HYP group, women with HSD reported better sexual function, higher sexual satisfaction, and lower odds of negative behavioral consequences. The findings suggest that, at least among women, hypersexuality should not be conflated with high sexual desire and frequent sexual activity. 相似文献
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Research on Eastern Europe stresses the weakness of its civil society and the lack of political and social involvement, neglecting the question: What do people themselves think it means to be a good citizen? This study looks at citizens’ definitions of good citizenship in Poland, Slovenia, the Czech Republic and Hungary, using 2002 European Social Survey data. We investigate mean levels of civic mindedness in these countries and perform regression analyses to investigate whether factors traditionally associated with civic and political participation are also correlated with citizenship norms across Eastern Europe. We show that mean levels of civic mindedness differ significantly across the four Eastern European countries. We find some support for theories on civic and political participation when explaining norms of citizenship, but also demonstrate that individual-level characteristics are differently related to citizenship norms across the countries of our study. Hence, our findings show that Eastern Europe is not a monolithic and homogeneous bloc, underscoring the importance of taking the specificities of countries into account. 相似文献
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Tanja?SchmidtEmail author Jan-Gerrit?Keil 《Organisationsberatung, Supervision, Coaching》2004,11(3):239-252
Success factors of executive coaching. A screening of the coaching scenery from the client’s point of viewThis survey, based on questionnaires, examines the success factors of one-to-one coaching from the client point of view. Firstly, ten success factors in coaching were established by means of factor analysis. Secondly, more extensive analysis shows that, contrary to previous research in this field, the “professional system” is not necessarily a determining success factor in coaching. As an exclusive instrument of staff development, coaching seems to be effective even without support from the professional system. The analysis also indicates that the clients perceive their coach as an advisor and confidant as regards role expectations. Furthermore, multiple regression analysis discloses the predictive effects of the two success factors “the coach’s qualification” and “the coach’s involvement” for the overall success of coaching from the client’s point of view. The overall success of coaching itself is established through three items: the clients’ attitudes towards coaching, their attitude concerning further coaching, and the extent to which their objectives were met in coaching. 相似文献
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Tanja Brøndsted Sejersen 《The International migration review》2008,42(3):523-549
Global developments in dual citizenship legislation highlight changes to conceptualizations of citizenship by increasing the focus on individual rights. Questions of inclusion and exclusion have been illuminated by the move toward wider acceptance of dual citizenship. To understand global patterns and developments in dual citizenship laws this article analyzes the legislation pertaining to dual citizenship in 115 countries. The results show how dual citizenship is becoming increasingly accepted – a development that has predominantly taken place within the last 20 years. A strong regional pattern is identified, supporting the argument that dual citizenship is spreading in a fashion similar to how the idea of citizenship expanded from Europe in the 19th and 20th centuries. Potential internal and external reasons for this development are discussed and individual countries’ experiences analyzed. 相似文献
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This research examines whether siblings and friends resemble each other in supportive behavior. Using a Dutch national sample of 6,289 individuals containing 12,578 relationships with siblings and friends, we investigated the relative importance of gender composition, geographical proximity, relationship quality, and contact frequency for support exchange with siblings and friends. Results show that, controlling for other influences, siblings exchange more practical and less emotional support. High relationship quality and contact frequency are positively related to exchange of emotional support with siblings more than with friends, as is—unexpectedly—living further away. Fewer differences exist in practical support exchange. In conclusion, siblings and friends are similar with regard to practical support but different when it comes to emotional support. 相似文献