Survey reveals emphasis on tying pay to quality. Physician executive pay increase holds steady near 7 percent

Double-digit increases were seen in three physician executive positions and there are strong indications that the patient safety movement is impacting the way physician executives are paid.     

Clinical effects of growth hormone on bone: a review

Growth hormone (GH) stimulates bone turnover. Deficiency of GH due to hypopituitarism is related to low bone mineral density and increased fracture risk. GH substitution increases and thus normalizes bone mineral density in these patients, which is one of a number of arguments for GH substitution in hypopituitarism. In contrast, a possible therapeutic use of GH in idiopathic osteoporosis and glucocorticoid-induced osteoporosis is speculative and not established. Reduction of osteoporosis risk is an argument brought up for a use of GH in healthy elderly persons (anti-aging medicine). However, since only very limited data are available yet, this cannot be based on scientific evidence, and there are important concerns about the safety of use of GH in healthy elderly persons.     

从全球人口百年(1950～2050)审视我国人口国策的抉择

基于“人口众多”这一基本国情,我国自20世纪80年代前后采取了严格控制人口增长的政策。对于这一政策应科学、全面地衡量其利害得失。文章利用全球人口资料和我国历次人口普查及人口预测资料,从人口规模、结构的发展变化作实证研究。最终认为,我国的人口国策是利大于弊。     

Evaluation of a weighted multiple comparison procedure

We consider the problem of accounting for multiplicity for two correlated endpoints in the comparison of two treatments using weighted hypothesis tests. Various weighted testing procedures are reviewed, and a more powerful method (a variant of the weighted Simes test) is evaluated for the general bivariate normal case and for a particular clinical trial example. Results from these evaluations are summarized and indicate that the weighted methods perform in a manner similar to unweighted methods. Copyright © 2005 John Wiley & Sons, Ltd.     

Permutational Multiple Testing Adjustments With Multivariate Multiple Group Data

We consider the multiple comparison problem where multiple outcomes are each compared among several different collections of groups in a multiple group setting. In this case there are several different types of hypotheses, with each specifying equality of the distributions of a single outcome over a different collection of groups. Each type of hypothesis requires a different permutational approach. We show that under a certain multivariate condition it is possible to use closure over all hypotheses, although intersection hypotheses are tested using Boole's inequality in conjunction with permutation distributions in some cases. Shortcut tests are then found so that the resulting testing procedure is easily performed. The error rate and power of the new method is compared to existing competitors through simulation of correlated data. An example is analyzed, consisting of multiple adverse events in a clinical trial.     

A Study of An Alternative School for Pregnant and/or Parenting Teens: Quantitative and Qualitative Evidence

In response to multiple problems faced by pregnant and parenting teens, many alternative school-based comprehensive programs have been established throughout the United States. By collecting data from a sample of enrollees of such a school-based comprehensive program and comparing them with data collected from a sample of non-enrollees, the present study systematically evaluates the program. The results of the study seem to suggest that the program participants were more likely to have higher educational aspiration, better reproductive health outcomes, higher contraceptive use, and more breast-feeding practice and intention than those of their non-participating counterparts. The implications of the study findings for comprehensive school-based program for pregnant and/or parenting teens are discussed.Ruhul Amin is a Senior Fellow at the Center for Health Disparities Solutions and Senior Research Scientist in the Institute for Urban Research, Morgan State University, Baltimore, MD 21239. Dorothy C. Browne is the Director of the Institute for Urban Research, Jamir Ahmed is a research assistant at the Center for Health Disparities Solutions and Takanori Sato is research assistants at the Institute for Urban Research, Morgan State University, Baltimore, MD 21239.