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1.
Staggered nested experimental designs are the most popular class of unbalanced nested designs. Using a special notation which covers the particular structure of the staggered nested design, this paper systematically derives the canonical form for the arbitrary m-factors. Under the normality assumption for every random variable, a vector comprising m canonical variables from each experimental unit is normally independently and identically distributed. Every sum of squares used in the analysis of variance (ANOVA) can be expressed as the sum of squares of the corresponding canonical variables. Hence, general formulae for the expectations, variances and covariances of the mean squares are directly obtained from the canonical form. Applying the formulae, the explicit forms of the ANOVA estimators of the variance components and unbiased estimators of the ratios of the variance components are introduced in this paper. The formulae are easily applied to obtain the variances and covariances of any linear combinations of the mean squares, especially the ANOVA estimators of the variance components. These results are eff ectively applied for the standardization of measurement methods.  相似文献   
2.
A key theme of Age-Friendly Honolulu’s initiative is intergenerational exchange. The initiative believes that youth need to be aware of aging issues, demographic change, and think critically about the potential impact on their lives. The goal of the Age-Friendly Honolulu Youth Engagement Initiative is to teach youth about the role of the built environment and community features in promoting active aging and engagement among older adults. This article describes a new program in the field that teaches youth and older adults to assess the built environment and then use design thinking and Minecraft (a popular video game in which players use 3-D blocks to create virtual lands) to develop and envision ideas to improve the livability of their neighborhood.  相似文献   
3.
Considering the integral relationship between public relations and democracy (Martinelli, 2011) coupled with the growing use of social media for democratic aims (Smith, 2011) the current study examines the effectiveness of Twitter as a public relations communications tool for congressional campaigns. Specifically, as a means of testing Twitter's effectiveness in informing and engaging voters, congressional candidate and political party Twitter use for all 435 U.S. House of Representatives races (N = 1284) are compared with 2010 election outcomes. Results indicate that candidates’ Twitter use significantly increased their odds of winning, controlling for incumbency and Party ID. Additionally, significant differences between incumbents’ and challengers’ Twitter use during the election cycle emerged, which has important implications for public relations practices aimed at achieving democratic outcomes.  相似文献   
4.
Introduction: It is well known that there is a reduction of circadian rhythm in blood testosterone levels with aging. Our previous report revealed that 3?mg of short-acting testosterone ointment (Glowmin: GL) elevated serum testosterone levels to within the physiological range for 4–6?h. The aim of this study was to clarify the clinical efficacy and safety of GL used topically once every morning, to enhance the circadian rhythm of testosterone, for late-onset hypogonadism (LOH).

Methods: A total of 61 LOH patients received 3?mg of GL topically once a day in the morning on scrotal skin for 24 weeks. The clinical efficacy of GL was evaluated by the aging males symptoms (AMS) scale, and blood sampling tests were measured before and after GL treatment.

Results: Mean patients age was 55.3?±?9.2 years old. Total AMS scores at 4, 12, and 24 weeks after GL treatments significantly decreased. The results of sub-analysis of AMS, including psychological, physical, and sexual factors also significantly improved after GL treatments. No severe adverse reactions or abnormal laboratory data were reported.

Conclusions: This study shows that TRT for LOH with once daily GL treatment supports testosterone circadian rhythm and should be considered to be an effective and safe therapy for LOH.  相似文献   
5.
This paper deals with obtaining an upper tolerance limit for a largest observation X(n) in an ordered sample of size n from a continuous distribution where the first m observations X(1) < X(2) < … < X(m), l ≤ m < n, have been observed. A criterion of “goodness” of tolerance limit is developed, and a method is given to obtain the best tolerance limit. This method is applied to exponential and Pareto distributions.  相似文献   
6.
Reduced k‐means clustering is a method for clustering objects in a low‐dimensional subspace. The advantage of this method is that both clustering of objects and low‐dimensional subspace reflecting the cluster structure are simultaneously obtained. In this paper, the relationship between conventional k‐means clustering and reduced k‐means clustering is discussed. Conditions ensuring almost sure convergence of the estimator of reduced k‐means clustering as unboundedly increasing sample size have been presented. The results for a more general model considering conventional k‐means clustering and reduced k‐means clustering are provided in this paper. Moreover, a consistent selection of the numbers of clusters and dimensions is described.  相似文献   
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8.
We experimentally found a negative effect of subsequent group conversations after media exposure on the audience's attitudes toward the covered organization, while we found sided media exposure to predict both attitudes and behavioral intentions relevant to the covered organization. The extent of conversational engagement immediately following media exposure also helped predict future word-of-mouth (WOM) intentions. These results highlight the roles of interpersonal interactions after media exposure to explain and predict public relations outcomes.  相似文献   
9.
An expansion formula for the coverage probability of prediction region based on a shrinkage estimator proposed by Joshi [Joshi, V. M. (1967). Inadmissibility of the usual confidence sets for the mean of a multivariate normal population. Ann. Math. Statist., 38, 1868–1875.] is obtained. Its error bound is evaluated in terms of a function of an unknown parameter. Applying this result, three types of asymptotic expansions are derived. These expansions show inadmissibility of the usual prediction region.  相似文献   
10.
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