A Bayesian inference of P(λ1<λ2) for two Poisson parameters

The statistical inference drawn from the difference between two independent Poisson parameters is often discussed in the medical literature. However, such discussions are usually based on the frequentist viewpoint rather than the Bayesian viewpoint. Here, we propose an index θ=P(λ_{1, post}<λ_{2, post}), where λ_{1, post} and λ_{2, post} denote Poisson parameters following posterior density. We provide an exact and an approximate expression for calculating θ using the conjugate gamma prior and compare the probabilities obtained using the approximate and the exact expressions. Moreover, we also show a relation between θ and the p-value. We also highlight the significance of θ by applying it to the result of actual clinical trials. Our findings suggest that θ may provide useful information in a clinical trial.     

Improved estimators for the common mean and ordered means of two normal distributions with ordered variances

We first consider the problem of estimating the common mean of two normal distributions with unknown ordered variances. We give a broad class of estimators which includes the estimators proposed by Nair (1982) and Elfessi et al. (1992) and show that the estimators stochastically dominate the estimators which do not take into account the order restriction on variances, including the one given by Graybill and Deal (1959). Then we propose a broad class of individual estimators of two ordered means when unknown variances are ordered. We show that in estimating the mean with larger variance, estimators which do not take into account the order restriction on variances are stochastically dominated by the proposed class of estimators which take into account both order restrictions. However, in estimating the mean with smaller variance, similar improvement is not possible even in terms of mean squared error. We also show a domination result in the simultaneous estimation problem of two ordered means. Further, improving upon the unbiased estimators of the two means is discussed.