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1.
In the development of many diseases there are often associated random variables which continuously reflect the progress of a subject towards the final expression of the disease (failure). At any given time these processes, which we call stochastic covariates, may provide information about the current hazard and the remaining time to failure. Likewise, in situations when the specific times of key prior events are not known, such as the time of onset of an occult tumour or the time of infection with HIV-1, it may be possible to identify a stochastic covariate which reveals, indirectly, when the event of interest occurred. The analysis of carcinogenicity trials which involve occult tumours is usually based on the time of death or sacrifice and an indicator of tumour presence for each animal in the experiment. However, the size of an occult tumour observed at the endpoint represents data concerning tumour development which may convey additional information concerning both the tumour incidence rate and the rate of death to which tumour-bearing animals are subject. We develop a stochastic model for tumour growth and suggest different ways in which the effect of this growth on the hazard of failure might be modelled. Using a combined model for tumour growth and additive competing risks of death, we show that if this tumour size information is used, assumptions concerning tumour lethality, the context of observation or multiple sacrifice times are no longer necessary in order to estimate the tumour incidence rate. Parametric estimation based on the method of maximum likelihood is outlined and is applied to simulated data from the combined model. The results of this limited study confirm that use of the stochastic covariate tumour size results in more precise estimation of the incidence rate for occult tumours. 相似文献
2.
This article considers the problem of estimating the parameters of Weibull distribution under progressive Type-I interval censoring scheme with beta-binomial removals. Classical as well as the Bayesian procedures for the estimation of unknown model parameters have been developed. The Bayes estimators are obtained under SELF and GELF using MCMC technique. The performance of the estimators, has been discussed in terms of their MSEs. Further, expression for the expected number of total failures has been obtained. A real dataset of the survival times for patients with plasma cell myeloma is used to illustrate the suitability of the proposed methodology. 相似文献
3.
Johan A. Oldekop Lorenza B. Fontana Jean Grugel Nicole Roughton Emmanuel A. Adu‐Ampong Gemma K. Bird Alex Dorgan Marcia A. Vera Espinoza Sara Wallin Daniel Hammett Esther Agbarakwe Arun Agrawal Nurgul Asylbekova Clarissa Azkoul Craig Bardsley Anthony J. Bebbington Savio Carvalho Deepta Chopra Stamatios Christopoulos Emma Crewe Marie‐Claude Dop Joern Fischer Daan Gerretsen Jonathan Glennie William Gois Mtinkheni Gondwe Lizz A. Harrison Katja Hujo Mark Keen Roberto Laserna Luca Miggiano Sarah Mistry Rosemary J. Morgan Linda L. Raftree Duncan Rhind Thiago Rodrigues Sonia Roschnik Flavia Senkubuge Ian Thornton Simon Trace Teresa Ore Ren Mauricio Valds Bhaskar Vira Nicola Yeates William J. Sutherland 《Development policy review : the journal of the Overseas Development Institute》2016,34(1):55-82
The Sustainable Development Goals (SDGs) herald a new phase for international development. This article presents the results of a consultative exercise to collaboratively identify 100 research questions of critical importance for the post‐2015 international development agenda. The final shortlist is grouped into nine thematic areas and was selected by 21 representatives of international and non‐governmental organisations and consultancies, and 14 academics with diverse disciplinary expertise from an initial pool of 704 questions submitted by 110 organisations based in 34 countries. The shortlist includes questions addressing long‐standing problems, new challenges and broader issues related to development policies, practices and institutions. Collectively, these questions are relevant for future development‐related research priorities of governmental and non‐governmental organisations worldwide and could act as focal points for transdisciplinary research collaborations. 相似文献
4.
Shirin Rai 《International Feminist Journal of Politics》2013,15(4):579-601
In this article I map out the major debates on global governance and the feminist critiques of the mainstream interventions in these debates. I argue that the shift from government to governance is a response to the needs of a gendered global capitalist economy and is shaped by struggles, both discursive and material, against the unfolding consequences of globalization. I suggest feminist interrogations of the concept, processes, practices and mechanisms of governance and the insights that develop from them should be centrally incorporated into critical revisionist and radical discourses of and against the concept of global governance. However, I also examine the challenges that the concept of global governance poses for feminist political practice, which are both of scholarship and of activism as feminists struggle to address the possibilities and politics of alternatives to the current regimes of governance. I conclude by suggesting that feminist political practice needs to focus on the politics of redistribution in the context of global governance. 相似文献
5.
Arun S 《Gender and development》1999,7(3):19-27
Drawing on a 12-month study, this paper explores the role of women in agriculture in Kerala, India. Despite claims that women enjoy high status in Kerala, economic, social, and cultural factors interplay to reinforce gender differences in ownership, control over, and access to critical agricultural resources, including land. Although women may gain access to land through inheritance, marriage, or informal networks, none of this guarantee effective control over it. The traditional rights of women to land have not been adequately recognized: the gender gap in the ownership and control of property is the only most significant contributor to the gender gap in the economic well-being, social status, and empowerment of women. The existing socioeconomic changes and crisis which render agricultural land as a main source of livelihood, is leading nair women's share of land being sold, with gains going to men, thus decreasing women?s ownership of land to the status of male-controlled dowry. The case of the Christian succession laws in Kerala illustrate that legal provisions alone can have a limited impact on changing gendered power structures. The role of women in agriculture needs to be recognized, and institutional support must be increased in order for women to gain access to agricultural inputs and technology, which in turn, leads to better agricultural practices and a higher income from farming in the country. Most importantly, there should be a concerted effort to enable women to function as independent farmers who control their own land. 相似文献
6.
Rai S 《Work (Reading, Mass.)》2002,18(1):15-22
Workplace aggression and violence is the fastest growing societal concerns in USA. The review of literature indicates that violence is a substantial contributor to occupational injuries and death. Preventative strategies for minimizing the risk of workplace violence include, cash-handling policies, physical separation of workers from customers, environmental modifications; good lighting, security devices, escort services, and employee training. Studies also suggest that as a preventive measure, employers will attract and retain the best workers if high-risk behaviors are discouraged and appropriate behaviors are supported. Proactive strategies reduce stress, increase productivity, and enhance creativity. A role for occupational therapy practitioners in the prevention of workplace violence is proposed. 相似文献
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8.
There has been little research on the health consequences of trafficking in women in Mexico and this study examines the effects of trafficking in women. Twenty internally trafficked women were interviewed in Monterrey city, Mexico, during the years 2007 and 2008. Although the study found that trafficking of women in Mexico results from multi-causal factors, we found that in general trafficked women suffer a wide range of physical and sexual violence. This has direct consequences on their physical and mental health and in particular their sexual health. 相似文献
9.
This paper is a reflective essay about our experience in conducting a participatory, community self-evaluation of a neighborhood revitalization effort in Milwaukee, Wisconsin. We took a controversial approach to evaluation by focusing on learning community dialogues as a vehicle for program evaluation. As we implemented our strategy, two sets of contradictions surfaced. The first points to the fundamental differences between conventional and constructivist research paradigms. The second centers around our focus on dialogue as a strategy for evaluation. In response to these contradictions we performed three complementary roles: program evaluator, process consultant, and learning facilitator. We are not implying that we performed an outstanding job in these roles. Rather, this article is our way of taking stock of what we learned about our practice as evaluators and how we may expand our repertoire of skills in the future. 相似文献
10.
Shirin M. Rai 《全球网;跨国事务杂志》2003,3(1):59-74
In this article I focus on a subaltern approach to knowledge networks by examining the process of setting up such a network, the South Asia Research Network (SARN) on Gender, Law and Governance. I reflect on the construction of discourses about ‘knowledge’ and ‘knowledge–makers’ and the issues of access that emerge as a result of these discourses and practices. I outline three aspects of a ‘politics of network(s)–ing’: the politics of process; the politics of outcome; and the politics of framing. I conclude that the borders of which we need to be aware are not just national borders but also borders of power. Knowledge networks are politically heterogeneous and for subaltern networks to have sustainable organizations as well as critical politics they need to be self–reflective and deliberative. 相似文献