Estimation of noncentrality parameters

We propose some estimators of noncentrality parameters which improve upon usual unbiased estimators under quadratic loss. The distributions we consider are the noncentral chi-square and the noncentral F. However, we give more general results for the family of elliptically contoured distributions and propose a robust dominating estimator.     

Estimates of fertility in Bangladesh

The attempt is made to estimate fertility levels in Bangladesh on the basis of data collected during the 1974 Census. In the 1st section attention is directed to providing an overall picture of the demographic situation in the country. Comparisons between the 1961 and 1974 data demonstrates that the 1974 Census data provide consistent results. Factors such as the degree of urbanization, literacy and economic participation rates--considered as indicators of development--all seem to show little progress during the intercensal period. The use of child/women ratios (CWRs) provides plausible evidence of the likelihood of a fertility decline. A decline in CWR values is small for "all areas" but a marked decline can be noted for "urban areas." The recorded mean number of children is less in 1974 than in 1961 for women under age 35 whereas for the older groups the 1974 Census shows higher mean numbers. The Bangladesh Fertility Survey (BFS) data result for the total fertility rate of 6.58 is very close to that estimated for the 1974 Census--6.59. The reverse survival method also indicates that birthrates have been lower during the 1969-1974 period.     

Health Disorder of Climate Migrants in Khulna City: An Urban Slum Perspective

As the most vulnerable climatic region in the country, Khulna City is increasingly experiencing climate‐change‐induced urban problems. For instance, occupancy by climate migrants (delete the term “illegal migrant”), drainage congestion, water logging and reduced fresh water availability are all increasing problems. In the last decade, the population in the city increased by more than 20 per cent due to migration from nearby climate vulnerable districts. This study explores the health disorders of climate migrants occupying the urban slums and squats of the Khulna City area. This study found that these climate migrants settled in the urban slums and squats and, as such, they do not have access to urban amenities such as clean drinking water, hygiene services, and health facilities. This study noted that these displaced people are at increased risk of health issues from unhygienic and overcrowded living conditions and from water and sanitation problems. They often suffer from different waterborne diseases, under‐nutrition and micronutrient deficiencies. This study suggests that there is a need for better planning, preparation and training in Bangladesh to which migrants move, including better training in health and related services on how to recognize and respond to health problems that may be slow to manifest. Education and training also need to be provided for the migrants themselves, to help them adapt culturally and to enhance their skills and potential for employment.     

Effect of a new selection procedure on adaptive estimation

Adaptive estimation of parameters of some failure time distributionsis considered. A new procedure named the F-procedure has beendeveloped for selecting an appropriate model out of two possible models by Pandey et.al. (1991). Applying this F-procedure adaptive estimatorsof parameters of exponential, Wei bull, inverse Gaussian (IG) and Wald failure time distributions have been proposed in this paper. Comparison of these estimators has been undertaken with MLE's of the respective parameters and with some previous adaptiveestimators by simulation of samples using the Monte Carlo method.Adaptive estimation of parameters of some failure time distributions is considered. A new procedure named the F-procedure has been developedfor selecting an appropriate model out of two possible models by Pandey et.al. (1991). Applying this F-procedure adaptive estimators of parameters of exponential, Wei bull, inverse Gaussian (IG) and Wald failure time distributions have been proposed in this paper. Comparison of these estimators has been undertaken with MLE's of the respective parameters and with some previous adaptive estimators by simulation of samples using the Monte Carlo method.     

Variable selection for survival data with a class of adaptive elastic net techniques

The accelerated failure time (AFT) models have proved useful in many contexts, though heavy censoring (as for example in cancer survival) and high dimensionality (as for example in microarray data) cause difficulties for model fitting and model selection. We propose new approaches to variable selection for censored data, based on AFT models optimized using regularized weighted least squares. The regularized technique uses a mixture of \(\ell _1\) and \(\ell _2\) norm penalties under two proposed elastic net type approaches. One is the adaptive elastic net and the other is weighted elastic net. The approaches extend the original approaches proposed by Ghosh (Adaptive elastic net: an improvement of elastic net to achieve oracle properties, Technical Reports 2007) and Hong and Zhang (Math Model Nat Phenom 5(3):115–133 2010), respectively. We also extend the two proposed approaches by adding censoring observations as constraints into their model optimization frameworks. The approaches are evaluated on microarray and by simulation. We compare the performance of these approaches with six other variable selection techniques-three are generally used for censored data and the other three are correlation-based greedy methods used for high-dimensional data.     

On E-Bayesian estimations for the cumulative hazard rate and mean residual life under generalized inverted exponential distribution and type-II censoring

Estimation of reliability and hazard rate is necessary in many applications. To this aim, different methods of estimation have been employed. Each method suffers from its own problems such as complexity of calculations, high risk and so on. Toward this end, this study employed a new method, E-Bayesian, for estimating the parametric functions of the Generalized Inverted Exponential distribution, which is one of the most noticeable distributions in lifetime studies. Relations are derived under a squared error loss function, type-II censoring and a conjugate prior. E-Bayesian estimations are obtained based on different priors of the hyperparameters to investigate the influence of different prior distributions on these estimations. The asymptotic behaviors of E-Bayesian estimations and relations among them have been investigated. Finally, a comparison among the maximum likelihood, Bayes and E-Bayesian estimations in different sample sizes are made, using a real data and the Monte Carlo simulation. Simulations show that the new presented method is more efficient than previous methods and is also easy to operate. Also, some comparisons among the results of Generalized Inverted Exponential distribution, Exponential distribution and Generalized Exponential distribution are provided.KEYWORDS: E-Bayesian estimation, generalized Inverted exponential distribution, type-II censoring, reliability, hazard rate, Monte Carlo simulation     

A semiparametric approach for modelling multivariate nonlinear time series

In this article, a semiparametric time‐varying nonlinear vector autoregressive (NVAR) model is proposed to model nonlinear vector time series data. We consider a combination of parametric and nonparametric estimation approaches to estimate the NVAR function for both independent and dependent errors. We use the multivariate Taylor series expansion of the link function up to the second order which has a parametric framework as a representation of the nonlinear vector regression function. After the unknown parameters are estimated by the maximum likelihood estimation procedure, the obtained NVAR function is adjusted by a nonparametric diagonal matrix, where the proposed adjusted matrix is estimated by the nonparametric kernel estimator. The asymptotic consistency properties of the proposed estimators are established. Simulation studies are conducted to evaluate the performance of the proposed semiparametric method. A real data example on short‐run interest rates and long‐run interest rates of United States Treasury securities is analyzed to demonstrate the application of the proposed approach. The Canadian Journal of Statistics 47: 668–687; 2019 © 2019 Statistical Society of Canada     

Modified profile likelihood estimation for the Weibull regression models in survival analysis

In this study, adjustment of profile likelihood function of parameter of interest in presence of many nuisance parameters is investigated for survival regression models. Our objective is to extend the Barndorff–Nielsen’s technique to Weibull regression models for estimation of shape parameter in presence of many nuisance and regression parameters. We conducted Monte-Carlo simulation studies and a real data analysis, all of which demonstrate and suggest that the modified profile likelihood estimators outperform the profile likelihood estimators in terms of three comparison criterion: mean squared errors, bias and standard errors.     

Analysis of microtubule dynamics using growth curve models

Microtubules are part of the structural network within a cell's cytoplasm, providing structural support as well as taking part in many of the cellular processes. A large body of data provide evidence that dynamics of microtubules in a cell is reponsible for the performance of many critical cellular functions such as cell division. In this article, we study the effect of four different isoforms of a protein tau on microtubule dynamics using growth curve models. The results show that a linear growth curve model is sufficient to explain the data. Moreover, we find that a mutated version of a 3-repeat tau protein has a similar effect as a 4-repeat tau protein on microtubule dynamics. The latter findings conform with the biological understanding of the effect of the protein tau on microtubule dynamics.