Fetal movement frequency and the effect of associated perinatal factors: Multicenter study

Background

Decreased fetal movements are associated with adverse perinatal outcomes, including stillbirth. Delayed maternal visits to a health care provider after perceiving decreased fetal movements are frequently observed in stillbirths. Informing pregnant women of the normal range of fetal movement frequency is essential in their earlier visits in order to prevent stillbirth.

共生教育

现在 ,各国都在以经济现代化为目标 ,尽可能发展和引进现代科学技术及其合理的思想观念 ,实现产业化 ,使国家富强 ,从而形成全球一体化的大交易圈。共生教育 ,就是讲授人们如何在这个大交易圈中生存的教育     

Excessively delayed maternal reaction after their perception of decreased fetal movements in stillbirths: Population-based study in Japan

Background

Fetal movement is the most common method to evaluate fetal well-being. Furthermore, maternal perception of decreased fetal movements is associated with perinatal demise. Previously, we showed that perception of decreased fetal movements was the most common reason for mothers visiting the outpatient department among those who had stillbirths in our region. Further investigation of stillbirths with decreased fetal movements is essential to find a possible way of preventing stillbirth.

Impacts per unit weight in catch by two types of fisheries on a chub mackerel population

By using data on the age-specific annual fecundity and catches-at-age by each fishery in a chub mackerel (Scomber japonicus) population in the Pacific Ocean off Japan during 1970 to 1992, we evaluated the long-term fluctuation in impacts of two types of fisheries on the chub mackerel population. The purse-seine fishery consistently had a larger impact on the population than did the dip-net fishery, mainly because the catch by the former was much larger than that by the latter. To evaluate impact per unit weight in catch, we calculated the average reproductive value per unit weight over individuals caught by each fishery as an indicator of efficient use of bioresource. Because the proportion of immature fish caught by the purse-seine fishery was usually larger than that by the dip-net fishery, the impact per unit weight in catch by the purse-seine fishery was not always less than that by the dip-net fishery.     

Assessing the prediction accuracy of cure in the Cox proportional hazards cure model: an application to breast cancer data

A cure rate model is a survival model incorporating the cure rate with the assumption that the population contains both uncured and cured individuals. It is a powerful statistical tool for prognostic studies, especially in cancer. The cure rate is important for making treatment decisions in clinical practice. The proportional hazards (PH) cure model can predict the cure rate for each patient. This contains a logistic regression component for the cure rate and a Cox regression component to estimate the hazard for uncured patients. A measure for quantifying the predictive accuracy of the cure rate estimated by the Cox PH cure model is required, as there has been a lack of previous research in this area. We used the Cox PH cure model for the breast cancer data; however, the area under the receiver operating characteristic curve (AUC) could not be estimated because many patients were censored. In this study, we used imputation‐based AUCs to assess the predictive accuracy of the cure rate from the PH cure model. We examined the precision of these AUCs using simulation studies. The results demonstrated that the imputation‐based AUCs were estimable and their biases were negligibly small in many cases, although ordinary AUC could not be estimated. Additionally, we introduced the bias‐correction method of imputation‐based AUCs and found that the bias‐corrected estimate successfully compensated the overestimation in the simulation studies. We also illustrated the estimation of the imputation‐based AUCs using breast cancer data. Copyright © 2014 John Wiley & Sons, Ltd.     

法益概念与多元的保护法益论

法益概念是作为社会的实在概念的“利益”与作为法的评价概念的“法的要保护性”相结合的产物,它能够发挥犯罪说明的机能、犯罪构成的机能、犯罪界限的机能、犯罪分类的机能和犯罪定数的机能等。历来的学说都是将一个刑法法规中只存在一个保护法益作为当然的前提,实际上在一个刑法法规中存在着复数的法益并存的情况,即,存在着复数的法益以“对等关系”或者“优劣关系”相结合的重叠并存形态和复数的保护法益并列且相互分离的并列并存形态。     

The Immediate Impact of the Fukushima Daiichi Accident on Local Property Values

The Fukushima Daiichi accident released huge amounts of radioactive material over a wide area. We can appreciate the geographical extent of radioactive contamination from the information published online by the Japanese government. Historically, this is an unprecedented situation, which allows “natural experimentation” to estimate the causal effects of radioactive contamination on our society. This study focused on property value losses caused by the accident and analyzed changes in land appraisals around the Fukushima Daiichi plant from July 2010 to July 2011 within the framework of hedonic approach. Thus, we estimated the short‐run impact of the contamination or the change in marginal value of proximity to the plant. The results suggest that the appraisals significantly and monotonically depreciated with increasing contamination levels. However, there was no evidence to suggest changes in the marginal value of proximity to the plant. A comparison between the appraisals and transaction prices indicates that this result could be interpreted as an underestimate of actual property value losses.     

Association of bioavailable estradiol levels and testosterone levels with serum albumin levels in elderly men

Estrogens are reported to be the essential sex steroid acting on some male physiological functions, and bioavailable estrogens comprise the free and albumin-bound fractions. Moreover, most of the bioavailable sex steroid is made up of albumin-bound fraction. We examined the age-related change in serum free, albumin-bound and bioavailable estradiol levels in comparison with each fraction of testosterone and its relationship with serum albumin level in elderly men. Albumin-bound as well as bioavailable estradiol levels declined with age, and their decreases were associated much more with the decrease of albumin level than the increase of sex-hormone binding globulin (SHBG) level in sixties and seventies, and similar results were recognized in the level of each fraction of testosterone, suggesting albumin levels have an important role for maintaining bioavailable sex steroid levels in males aged over sixty. Moreover, our study showed that SHBG levels associated inversely with bioavailable sex steroid levels particularly when serum albumin level was low. It seems likely that the decrease of bioavailable estradiol as well as testosterone is induced by the decrease of albumin-bound fractions in combination with the increase of SHBG-bound fractions in males aged over sixty, and that their physical characteristics of aging could be induced by the decrease of albumin-bound fractions caused by the decrease of serum albumin regardless of total sex steroid levels.     

Impact factors of purse seine net and dip net fisheries on a chub mackerel population

There are two major kinds of fisheries for the chub mackerel in Japan. The purse seine net fishery exploits young and adult fish during the foraging season, while the dip net fishery exploits fish before and during the spawning season. To compare the damage to the chub mackerel stock caused by purse seine net and dip net fisheries, we introduced impact factors of the two kinds of fisheries on the two kinds of fisheries and estimated number of eggs spawned in 1982. We defined the impact factor as the ratio of the average reproductive value of individuals caught by each fishery to the reproductive value at maturity. The number of individuals caught by the purse seine net fishery was 66 times larger than the number caught by the dip net fishery, while the impact factor of the former was 84% of that of the latter. Thus, the total damage caused by the purse seine net fishery was much higher than the damage caused by the dip net fishery. We can evaluate the damage caused by mortality factors on endangered species using this method.     

Nuclear Power‐Related Facilities and Neighboring Land Price: A Case Study on the Mutsu‐Ogawara Region,Japan

From the perspective of risk, nuclear‐power‐related facilities (NPRFs) are often regarded as locally undesirable land use. However, construction of NPRFs contributes to social infrastructural improvement and job creation in the host communities. This raises a question: How large are these positive and negative effects? To approach this question from an economic viewpoint, we estimated the hedonic land price function for the Mutsu‐Ogawara region of Japan from 1976 to 2004 and analyzed year‐by‐year fluctuations in land prices around the NPRFs located there. Land prices increased gradually in the neighborhood of the nuclear fuel cycle facilities (NFCFs) in Rokkasho Village, except for some falling (i) from 1982 to 1983 (the first official announcement of the project of construction came in 1983), (ii) from 1987 to 1988 (in 1988, the construction began and opposition movements against the project reached their peak), and (iii) from 1998 to 1999 (the pilot carry‐in of spent fuels into the reprocessing plant began in 1998). Land prices around the Higashidori Nuclear Power Plant decreased during the period 1981–1982, when the Tohoku Electric Power Corp. and Tokyo Electric Power Corp. announced their joint construction plan. On the other hand, we obtained some results, even though not significant, indicating that land prices around Ohminato and Sekinehama harbors changed with the arrival and departure of the nuclear ship Mutsu, which suffered a radiation leak in 1974.