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1.
We propose a procedure to identify a lowest dose having greater effect than a threshold dose under the assumption of monotonicity of dose mean response in dose response test. So, we use statistics based on contrasts among sample means and apply a group sequential procedure to our procedure to identify effectively the dose. If we can identify the dose at an early step in the sequential test, since we can terminate the procedure with a few observations, the procedure is useful from an economical point of view. In a simulation studies, we compare the superiority among these procedures based on three contrasts.  相似文献   
2.
This article deals with a stochastic optimal control problem for a class of buffered multi-parts flow-shops manufacturing system. The involved machines are subject to random breakdowns and repairs. The flow-shop under consideration is not completely flexible and hence requires setup time and cost in order to switch the production from a part type to another, this changeover is carried on the whole line. Our objective is to find the production plan and the sequence of setups that minimise the cost function, which penalises inventories/backlogs and setups. A continuous dynamic programming formulation of the problem is presented. Then, a numerical scheme is adopted to solve the obtained optimality conditions equations for a two buffered serial machines two parts case. A complete heuristic policy, based on the numerical observations which describe the optimal policies in system states, is developed. It will be shown that the obtained policy is a combination of a KANBAN/CONWIP and a modified hedging corridor policy. Moreover, based on our observations and existent research studies extension to cover more complex flow-shops is henceforth possible. The robustness of such a policy is illustrated through sensitivity analysis.  相似文献   
3.
In recent years, population health research has focused on understanding the determinants of later-life health. Two strands of that work have focused on (1) international comparisons of later-life health and (2) assessing the early-life origins of disease and disability and the importance of life course processes. However, the less frequently examined intersection of these approaches remains an important frontier. The present study contributes to the integration of these approaches. We use the Health and Retirement Study family of data sets and a cohort dynamic approach to compare functional health trajectories across 12 high-income countries and to examine the role of life course processes and cohort dynamics in contributing to variation in those trajectories. We find substantial international variation in functional health trajectories and an important role of cohort dynamics in generating that variation, with younger cohorts often less healthy at comparable ages than the older cohorts they are replacing. We further find evidence of heterogeneous effects of life course processes on health trajectories. The results have important implications for future trends in morbidity and mortality as well as public policy.  相似文献   
4.
For square contingency tables with ordered categories, there may be some cases that one wants to analyze them by considering collapsed tables with some adjacent categories combined in the original table. This paper proposes three kinds of new models which have the structure of point-symmetry (PS), quasi point-symmetry and marginal point-symmetry for collapsed square tables. This paper also gives a decomposition of the PS model for collapsed square tables. The father's and his daughter's occupational mobility data are analyzed using new models.  相似文献   
5.
Several upper bounds on the maximum number of constraints for s-symbol balanced arrays of strength t are given. Some bounds derived here include the results obtained by Rafter and Seiden (1974), Chopra (1982, 1983) and Saha, Mukerjee and Kageyama (1983).  相似文献   
6.
The display and regulation of child anger in family interaction was coded in a sample of 240 boys and girls at child age 6, and coded using the Specific Affect Coding System. Child antisocial behavior was longitudinally assessed, beginning in kindergarten. Pooled‐ and family‐level analyses were used to assess hazard rates for child anger. Parents’ ability to modulate their own emotions and negative behavior, and children's ability to down‐regulate anger were associated with increased latency for child anger. Hazard for child anger increased as parents’ insensitive and negative responses toward the child cumulated during family interaction. Macro‐level, non‐hazard analyses indicated that chronic levels of child antisocial behavior were associated with the frequency of parental negative behavior, but not with the frequency of child anger. Micro‐level hazard analyses indicated that children's ability to regulate anger was related to chronic levels of child covert but not overt antisocial behavior.  相似文献   
7.
Abstract

This paper considers the optimization problems for a consecutive-2-out-of-n:G system where n is considered to be fixed or random. When the number of components is constant, the optimal number of components and the optimal replacement time are discussed by minimizing the expected cost rates. Furthermore, we focus on the above discussions again when n is a random variable. We give an approximate value of MTTF and propose the preventive replacement policy, respectively.  相似文献   
8.
Manufacturers want to assess the quality andreliability of their products. Specifically, they want to knowthe exact number of failures from the sales transacted duringa particular month. Information available today is sometimesincomplete as many companies analyze their failure data simplycomparing sales for a total month from a particular departmentwith the total number of claims registered for that given month.This information—called marginal count data—is, thus,incomplete as it does not give the exact number of failures ofthe specific products that were sold in a particular month. Inthis paper we discuss nonparametric estimation of the mean numbersof failures for repairable products and the failure probabilitiesfor nonrepairable products. We present a nonhomogeneous Poissonprocess model for repairable products and a multinomial modeland its Poisson approximation for nonrepairable products. A numericalexample is given and a simulation is carried out to evaluatethe proposed methods of estimating failure probabilities undera number of possible situations.  相似文献   
9.
Public Response to the Tokai Nuclear Accident   总被引:2,自引:0,他引:2  
Tsunoda Katsuya 《Risk analysis》2001,21(6):1039-1046
This article discusses the influence of the September 30, 1999 nuclear accident in Tokai village (Japan) on the public's attitudes toward nuclear power in Japan. The data used in this report were taken from the results of two surveys conducted mainly to measure the attitudes of the Japanese public with regard to the use of nuclear power in Japan. The first survey was done before the accident in District 23 in Tokyo and also in Osaka and Nagoya. The second survey, which took place after the accident in District 23 in Tokyo and in Osaka and Nagoya, also included residents in a number of other cities of various sizes throughout Japan. The results of the two surveys showed that (1) acceptability of and trust in nuclear power operation had decreased, (2) perceived accident likelihood and public interest had significantly increased, and (3) there had been neither significant nor even a small change in the public's self-rated knowledge about nuclear power or their distrust of the government. The results also showed that the ratio of nuclear power generation opponents to total respondents had considerably increased (7% to 23%) whereas nuclear power generation supporters had moderately decreased (1% to 12%).  相似文献   
10.
A new moment estimator of the dispersion parameter of the beta-binomial distribution is proposed. It is derived by the method of moments which is constrained to satisfy the unbiasedness of the estimating equation. It gives a better performance than those of the usual moment estimators and the stabilized moment estimator proposed by Tamura & Young. The bias of the estimator is smaller than that of the maximum likelihood estimate in a wide range of parameter space.  相似文献   
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