What to Do at Low Doses: A Bounding Approach for Economic Analysis

To quantify the health benefits of environmental policies, economists generally require estimates of the reduced probability of illness or death. For policies that reduce exposure to carcinogenic substances, these estimates traditionally have been obtained through the linear extrapolation of experimental dose-response data to low-exposure scenarios as described in the U.S. Environmental Protection Agency's Guidelines for Carcinogen Risk Assessment (1986). In response to evolving scientific knowledge, EPA proposed revisions to the guidelines in 1996. Under the proposed revisions, dose-response relationships would not be estimated for carcinogens thought to exhibit nonlinear modes of action. Such a change in cancer-risk assessment methods and outputs will likely have serious consequences for how benefit-cost analyses of policies aimed at reducing cancer risks are conducted. Any tendency for reduced quantification of effects in environmental risk assessments, such as those contemplated in the revisions to EPA's cancer-risk assessment guidelines, impedes the ability of economic analysts to respond to increasing calls for benefit-cost analysis. This article examines the implications for benefit-cost analysis of carcinogenic exposures of the proposed changes to the 1986 Guidelines and proposes an approach for bounding dose-response relationships when no biologically based models are available. In spite of the more limited quantitative information provided in a carcinogen risk assessment under the proposed revisions to the guidelines, we argue that reasonable bounds on dose-response relationships can be estimated for low-level exposures to nonlinear carcinogens. This approach yields estimates of reduced illness for use in a benefit-cost analysis while incorporating evidence of nonlinearities in the dose-response relationship. As an illustration, the bounding approach is applied to the case of chloroform exposure.     

A LOTTO SYSTEMS PROBLEM

A Lotto Systems bet allows the player to nominate n numbers from which (s)he believes the winning six numbers will be drawn, and to bet on all combinations of six of these n numbers. Assume that the winning six numbers come from the nominated n. How many combinations must be entered to guarantee that one combination will include at least five of the winning six numbers? The problem is generalized in this paper, and the method of simulated annealing is used to find solutions for various situations. The case where two supplementary numbers are drawn after the initial six winning numbers is also considered.     

An exploratory study of gambling cross addictions

A growing body of empirical and theoretical research has concentrated on the overlaps and commonalities among chemical and non-chemical (behavioural) addictions. Pathological gambling has perhaps been the most widely researched behavioural addiction and some of this research has concerned the co-existing links between pathological gambling and alcohol/drug addiction in both the gambling substance abuser and the substance abusing gambler (i.e. cross addiction). This study was of an exploratory nature and attempted to gather information and data regarding gambling cross addictions in the UK. To achieve this, 456 letters were sent to all drug and alcohol helping agencies in England requesting such information. This yielded 210 returns (46% response rate). Results indicated that gambling cross addictions occur in both adults and adolescents and were almost exclusively a male condition. However, it must be noted only just over half of the responding agencies had encountered gambling cross addiction and reasons for this are speculated. Results also indicated the existence of various cross addicted subgroups including an adolescent subgroup who were addicted to fruit machines and abused solvents. Future research ideas are also discussed.A more detailed version of this paper is available from the author on request.     

Sexual Behavior in Parked Cars Reported by Midwestern College Men and Women

In an anonymous survey of 195 men and 511 women (M_age = 19.8) at a small Midwestern university, 119 men (61%) and 303 women (59.5%) reported that they had engaged in sex while parked. Of these 422, 14% lost their virginity in a parked car. Having sex in parked cars was more likely to involve relational dating partners than hookups. In most recent incidents, the majority of respondents were with a serious but noncohabiting romantic partner (56.9%) in the back seat (63.4%) of a standard car (56.4%) parked out in the country (56.0%). The most common sexual acts were penile-vaginal sex and genital touching, reported by 84.6% and 57.5% of respondents, respectively. Condoms were used by 58.2% of respondents. Less than 1% of respondents reported sexually transmitted infections (STIs) or pregnancy outcomes. These data, including personal stories of memorable incidents, revealed that despite discomfort, body bumps, and risk of being caught, sex while parked was primarily a positive sexual and romantic experience for both men and women. A dark side of parked-car sex existed in that 2.5% of men and 4.3% of women reported being sexually coerced. The future study of sex in parked cars in urban environments is recommended.     

The star-shaped Λ-coalescent and Fleming–Viot process

The star-shaped Λ-coalescent and corresponding Λ-Fleming–Viot process, where the Λ measure has a single atom at unity, are studied in this article. The transition functions and stationary distribution of the Λ-Fleming–Viot process are derived in a two-type model with mutation. The distribution of the number of non-mutant lines back in time in the star-shaped Λ-coalescent is found. Extensions are made to a model with d types, either with parent-independent mutation or general Markov mutation, and an infinitely-many-types model, when d → ∞. An eigenfunction expansion for the transition functions is found, which has polynomial right eigenfunctions and left eigenfunctions described by hyperfunctions. A further star-shaped model with general frequency-dependent change is considered and the stationary distribution in the Fleming–Viot process derived. This model includes a star-shaped Λ-Fleming–Viot process with mutation and selection. In a general Λ-coalescent explicit formulae for the transition functions and stationary distribution, when there is mutation, are unknown. However, in this article, explicit formulae are derived in the star-shaped coalescent.     

Beyond the urban stream syndrome: organic matter budget for diagnostics and restoration of an impaired urban river

In response to water quality standard violations linked to excessive organic matter (OM) and a lack of sampling data informing the Total Maximum Daily Load (TMDL), an organic matter budget was created to quantify and identify sources of OM in the lower Jordan River (Salt Lake City, UT). By sampling dissolved, fine and coarse particulate OM, as well as measuring ecosystem metabolism at seven different sites, the researchers aimed to identify the origin of excess OM, and understand pathways by which different size classes of the OM pool are generated. The dissolved fraction (DOM; 94 %) was found to be the dominant form of OM transported within the river with fine particulate organic matter (FPOM; 6 %) the second most abundant, and coarse particulate organic matter (CPOM; 1 %) transport relatively insignificant in the overall OM budget. Primary production exceeded respiratory losses in the upper river, and this, along with OM inputs from two tributaries (where water reclamation facilities discharge into the river) delivered excess OM to the impaired lower reaches. Increasing stream metabolism index (SMI) with distance downstream (>1 in the lower river) further demonstrated that transport of excessive organic matter into the lower river was from upstream sources and not due to lateral inputs. This simple approach to characterizing the organic matter budget as it relates to water quality in the Jordan River was effective and could serve as a model for future studies attempting to quantify and identify sources of OM in urban ecosystems.     

Betting is Loving and Bettors are Predators: A Conceptual Metaphor Approach to Online Sports Betting Advertising

The legalisation of online gambling in multiple territories has caused a growth in the exposure of consumers to online sports betting (OSB) advertising. While some efforts have been made to understand the visible structure of betting promotional messages, little is known about the latent components of OSB advertisements. The present study sought to address this issue by examining the metaphorical conceptualisation of OSB advertising. A sample of Spanish and British television OSB advertisements from 2014 to 2016 was analysed (N = 133). Following Lakoff and Johnson’s conceptual metaphor theory, four main structural metaphors that shaped how OSB advertising can be understood were identified: betting as (1) an act of love, (2) a market, (3) a sport, and (4) a natural environment. In general, these metaphors, which were found widely across 29 different betting brands, facilitated the perception of bettors as active players, with an executive role in the sport events bet upon, and greater control over bet outcomes.     

The Impact of Speed of Play in Gambling on Psychological and Behavioural Factors: A Critical Review

Conceptually, there is a common association between gambling games with fast speeds of play and problem gambling. This relationship however, is largely correlational in nature, which comes at the expense of carefully controlled empirical investigation. Research that does exist aimed towards investigating the impact of gambling speeds on psychological and behavioural factors, is in its relative infancy, and the research possesses disparate methodologies and variables of interest. The aims of the current review is therefore to evaluate and summarise the existing body of evidence relating to speed of play in gambling, as well as discuss how this evidence can be used to inform harm minimisation approaches aimed at facilitating self-control during gambling. Eleven studies were selected for review based on the inclusion criteria, comprising nine experimental and two qualitative studies (one self-report focus group study and one observational study). There was a consistent finding across studies that games with faster speeds of play were preferred and rated as more exciting for all gamblers, ranging from non-problem to problem gamblers. Of concern, was the repeated finding that fast games are particularly appealing to those suffering with a gambling problem. Behavioural results were more inconsistent across studies, though the general trend supports the notion that games with faster speeds of play encourage more wagers, longer game play, and caused players, particularly problem gamblers, to experience difficulty in ceasing gambling. The implications of these findings for gambling policy, harm minimisation approaches, and future research are discussed.