'Making Culture Matter': Symbolic,Spatial and Social Boundaries between Uyghurs and Han Chinese

This article illustrates how Uyghurs in the 1990s defined and reinforced contemporary Uyghur national identity in relation to Xinjiang's growing Han Chinese population. Adopting Barth's theory of fluid and negotiable ethnic boundaries, it focuses on the notion of change. While Uyghurs are currently activating and exaggerating certain religio-cultural differences--in particular the avoidance of pork--as a means of ensuring symbolic, spatial and social segregation from the Han, those criteria did not prevent interaction to the same extent in the past; nor do they prevent Uyghurs from making concessions when it benefits them to do so. It is argued that it is not religio-cultural differences per se that lie at the root of increased tensions between Uyghurs and Han Chinese, but changing social, political and economic contexts: on the one hand, growing Uyghur perceptions of socio-economic inequalities between themselves and the Han (the 'internal factor') and, on the other, the vast changes within the international political arena since the late 1980s (the 'external factor').     

Estimation of dependence between paired correlated failure times in the presence of covariate measurement error

Summary. In many biomedical studies, covariates are subject to measurement error. Although it is well known that the regression coefficients estimators can be substantially biased if the measurement error is not accommodated, there has been little study of the effect of covariate measurement error on the estimation of the dependence between bivariate failure times. We show that the dependence parameter estimator in the Clayton–Oakes model can be considerably biased if the measurement error in the covariate is not accommodated. In contrast with the typical bias towards the null for marginal regression coefficients, the dependence parameter can be biased in either direction. We introduce a bias reduction technique for the bivariate survival function in copula models while assuming an additive measurement error model and replicated measurement for the covariates, and we study the large and small sample properties of the dependence parameter estimator proposed.     

A sea change on the island continent: frameworks for risk assessment,prevention and intervention in child health in Australia

This article overviews prevention and early intervention approaches focusing specifically on their relevance to the health of children and young people in Australia. Australian public health has a sound track record although concealed within the aggregate profile are a number of sub-populations with poorer health indicators. Recognition of this has increased efforts to improve the health of children and young people especially in exploring the impact of social environments within the communities where children are raised. This paper examines emerging research in this area drawing out key lessons and learning from Australian experience in the field of early intervention and prevention in community settings.     

Chinese version of the OSI: A validation study

This article examines the construct validity of the Occupational Stress Indicator (OSI) in its Chinese version as well as its criterion-oriented validity against self-reported data on absenteeism and accidents, using a final sample of 1054 workers in the Chinese manufacturing and power industries. The divergent and convergent validities of five of the OSI scales—Job satisfaction, Physical ill-health, Mental ill-health, Type A behaviour and Control—were examined by a multimethod-multitrait matrix technique. Results indicated that the Chinese OSI had fairly good validity in relation to other well-established measures as well as relevant organizational behaviours.     

Effects of testosterone replacement therapy withdrawal and re-treatment in hypogonadal elderly men upon obesity,voiding function and prostate safety parameters

Whether testosterone replacement therapy (TRT) is a lifelong treatment for men with hypogonadism remains unknown. We investigated long-term TRT and TRT withdrawal on obesity and prostate-related parameters. Two hundred and sixty-two hypogonadal patients (mean age 59.5) received testosterone undecanoate in 12-week intervals for a maximum of 11 years. One hundred and forty-seven men had TRT interrupted for a mean of 16.9 months and resumed thereafter (Group A). The remaining 115 patients were treated continuously (Group B). Prostate volume, prostate-specific antigen (PSA), residual voiding volume, bladder wall thickness, C-reactive protein (CRP), aging male symptoms (AMS), International Index of erectile function – erectile function (IIEF-EF) and International Prostate Symptoms Scores (IPSS) were measured over the study period with anthropometric parameters of obesity, including weight, body mass index (BMI) and waist circumference. Prior to interruption, TRT resulted in improvements in residual voiding volume, bladder wall thickness, CRP, AMS, IIEF-EF, IPSS and obesity parameters while PSA and prostate volume increased. TRT interruption reduced total testosterone to hypogonadal levels in Group A and resulted in worsening of obesity parameters, AMS, IPSS, residual voiding volume and bladder wall thickness, IIEF-EF and PSA while CRP and prostate volume were unchanged until treatment resumed whereby these effects were reversed. TRT interruption results in worsening of symptoms. Hypogonadism may require lifelong TRT.     

Brief Emotion Focused Family Therapy: An Intervention for Parents of Children and Adolescents with Mental Health Issues

This study evaluated the 2‐day intensive modality of Emotion Focused Family Therapy (EFFT). The intervention attempts to prepare parents to take a primary role in their child's recovery from a range of mental health issues. One hundred and twenty‐four parents completed the intervention and provided data a week prior to intervention, post‐intervention and at 4‐month follow‐up. Results include significantly reduced parent blocks and increased parental self‐efficacy in relation to involvement in their child's recovery, as well as significant improvement in child symptomatology. The findings confirm positive results from an earlier pilot study involving eating disorders and demonstrate the potential for EFFT as an intervention for a range of clinical problems in children and youth.     

Utilizing Bayesian predictive power in clinical trial design

The Bayesian paradigm provides an ideal platform to update uncertainties and carry them over into the future in the presence of data. Bayesian predictive power (BPP) reflects our belief in the eventual success of a clinical trial to meet its goals. In this paper we derive mathematical expressions for the most common types of outcomes, to make the BPP accessible to practitioners, facilitate fast computations in adaptive trial design simulations that use interim futility monitoring, and propose an organized BPP-based phase II-to-phase III design framework.