Society's search for a legal and ethical basis of physician-assisted suicide

A review of the way physician-assisted suicide (PAS) is being addressed in the United States reveals three models, each functioning out of distinctive concepts of autonomy: (1) litigation, which utilizes philosophical autonomy; (2) legislation, which utilizes political autonomy; and (3) act of conscience by a physician, which utilizes consumer autonomy. Each model raises a correspondingly distinct set of ethical questions and challenges centered around their point of reference-the judicial system, voters, or the doctor-patient relationship. In the end, however, efforts to resolve the challenge of PAS will falter if they do not go beyond these models of autonomy. Religious institutions offer a more constructive setting for facing the life and death decisionmaking of PAS. The challenge for religion is to address PAS in solidarity with sufferers, physicians, and the community, rather than retreating into iconoclastic dogmas.     

The push for transgender inclusion: Exploring boundary spanning in the gay–straight alliance

Gay–straight alliance (or gender‐sexuality alliance; GSA) is a high‐school based club aimed at providing a safer environment for sexual and gender minority youth as well as their straight allies. Yet, as a club historically rooted in addressing sexual orientation‐related concerns, less attention has been given to understanding the changing relational dynamics of internal GSA activities aimed at expanding membership boundaries through the promotion of transgender inclusivity. I address this by bridging existing scholarship on GSAs, social movements, and the sociology of culture to showcase the impact boundary‐spanning strategies are having on GSA mobilization, in‐group solidarity, and external political and social activism. My findings reveal that membership boundary negotiations around gender diversity issues are shifting the social landscape of these clubs. Emerging barriers that impede boundary‐spanning efforts are also highlighted and discussed. More broadly, I generate new theoretical insights into how boundary spanning can shape political and social activism as well as offer promising future research directions in this area.     

100 key research questions for the post‐2015 development agenda

The Sustainable Development Goals (SDGs) herald a new phase for international development. This article presents the results of a consultative exercise to collaboratively identify 100 research questions of critical importance for the post‐2015 international development agenda. The final shortlist is grouped into nine thematic areas and was selected by 21 representatives of international and non‐governmental organisations and consultancies, and 14 academics with diverse disciplinary expertise from an initial pool of 704 questions submitted by 110 organisations based in 34 countries. The shortlist includes questions addressing long‐standing problems, new challenges and broader issues related to development policies, practices and institutions. Collectively, these questions are relevant for future development‐related research priorities of governmental and non‐governmental organisations worldwide and could act as focal points for transdisciplinary research collaborations.     

The incidence of metabolic risk factors in an inpatient psychiatric setting

Our study examines risk factors for metabolic syndrome on admission to an acute psychiatric facility and the incidence of medical referrals at discharge. Data on demographics, risk factors for metabolic syndrome, other health risk factors, medications, related diagnoses, and primary care providers and referrals were collected from 125 psychiatric patient charts. Comparison analysis was done for two groups: those with two or more risk factors for metabolic syndrome and those with less than two risk factors. Differences between groups were statistically significant for age, waist circumference, body mass index, high-density lipoprotein, triglycerides, and fasting glucose levels. Few patients were referred to their primary care provider for follow-up care. This study has clinical implications for improving assessment of psychiatric patients at risk for developing metabolic syndrome, for designing interventions to help patients adopt lifestyle changes to mitigate these risks, and for working toward fuller integration of psychiatric and primary care.     

Revisiting das gupta: Refinement and extension of standardization and decomposition

Standardization and decomposition are established and widely used demographic techniques for comparing rates and means between groups with differences in composition. The difference in rates and means has heretofore been resolved in terms of the contribution of variables to compositional effects for each variable and an overall rate effect. This study demonstrates that the resolution of differences is attainable at the categorical level for both compositional effects and rate effects. Refinements to Das Gupta’s equations yield a complete decomposition because of the additivity of categorical compositional and rate effects. Other refinements allow the decomposition of polytomous variables. Extensions to the method provide for the decomposition of the standard deviation and the multivariate index of dissimilarity.     

Reducing poverty and inequality through tax-benefit reform and the minimum wage: the UK as a case-study

Atkinson’s book Inequality: What Can Be Done? (Harvard University Press, 2015) sets out a range of concrete proposals aimed at reducing income inequality, which cover a very broad span but include major changes to the income tax and social transfers system and the minimum wage. These are framed with specific reference to the UK but have much broader relevance in demonstrating how substantial the impact on inequality of such measures could be. This paper assesses the first-round effects of these tax, transfer and minimum wage reforms on income inequality and poverty based on a microsimulation approach using EUROMOD. The reforms involve a significantly more progressive income tax structure, a major increase in the minimum wage to the level which is estimated to represent the ‘Living Wage’, and alternative routes to reforming social transfers – either to strengthen the social insurance element or to restructure the entire system as a Participation Income (a variant of Basic/Citizen’s Income). The results show how the first-round effects of either set of tax and transfer proposals would be to substantially reduce the extent of income inequality and relative income poverty and the paper draws out how the two approaches differ in their effects. The additional impact of raising the minimum wage to the Living Wage is modest, reflecting in particular the position of beneficiaries in the household income distribution and the offsetting effects on household income of the withdrawal of means-tested cash transfers.     

Disciplining qualitative decision exercises: Aspects of a transempirical protocol

This paper defines and defends certain procedural and instrumental initiatives taken to constitute a transempirical protocol. This protocol is intended to provide one avenue for extending the bounds of rationality to decision exercises where there are only limited opportunities for effecting objective or empirical discipline. That is, the practical purpose of the protocol's facilities is to help prevent decision exercises that must be conducted in the face of a signal sparsity of objective/empirical predicates from degenerating into an uncontrolled retreat from reason.The paper is divided into two essentially self-contained parts. Part I will try to establish the rationale for the transempirical protocol in light of the reach and limits of other decision-theoretic platforms, and briefly introduce the set of provisions it entails. Part II will then go through a technical elaboration of these provisions, suggesting how they might be brought towards operational significance.     

A Weighted Composite Dose – Response Model For Human Salmonellosis

This article describes the development of a weighted composite dose – response model for human salmonellosis. Data from previously reported human challenge studies were categorized into two different groups representing low and moderately virulent/pathogenic Salmonella strains based on a disease end point. Because epidemiological data indicate that some Salmonella strains are particularly pathogenic, and in the absence of human feeding study data for such strains, Shigella dysenteriae was used as a proxy for highly virulent strains. Three single-hit dose – response models were applied to the human feeding study data and evaluated for best fit using maximum likelihood estimation: (1) the exponential (E-1pop), (2) the two-subpopulation exponential (E-2pop), and (3) the Beta-Poisson (BP). Based on the goodness-of-fit test, the E-1pop and BP were the best-fit models for low and moderately virulent/pathogenic Salmonella strains, and the E-2pop and BP models were better for highly virulent/pathogenic strains. Epistemic analysis was conducted by determining the degree of confidence associated with the selected models, which was found to be 50%/50% (E-1pop/BP) for low and moderately pathogenic Salmonella strains, and 9.8%/90.2% (E-2pop/BP) for highly virulent strains. The degree of confidence for each component model and variations in the proportion of strains within each virulence/pathogenicity category were incorporated into the overall composite model. This study describes the influence of variation in strain virulence and host susceptibility on the shape of the population dose – response relationship.